Isoform-specific gene disruptions reveal a role for the V-ATPase subunit a4 isoform in the invasiveness of 4T1-12B breast cancer cells
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Title
Isoform-specific gene disruptions reveal a role for the V-ATPase subunit a4 isoform in the invasiveness of 4T1-12B breast cancer cells
Authors
Keywords
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Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 294, Issue 29, Pages 11248-11258
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2019-06-06
DOI
10.1074/jbc.ra119.007713
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Note: Only part of the references are listed.- Essential Role of the a3 Isoform of V-ATPase in Secretory Lysosome Trafficking via Rab7 Recruitment
- (2018) Naomi Matsumoto et al. Scientific Reports
- Activation of PI3K, Akt, and ERK during early rotavirus infection leads to V-ATPase-dependent endosomal acidification required for uncoating
- (2018) Mahmoud Soliman et al. PLoS Pathogens
- The Function of V-ATPases in Cancer
- (2016) Laura Stransky et al. PHYSIOLOGICAL REVIEWS
- The a3 isoform of subunit a of the vacuolar ATPase localizes to the plasma membrane of invasive breast tumor cells and is overexpressed in human breast cancer
- (2016) Kristina Cotter et al. Oncotarget
- Preclinical Mouse Cancer Models: A Maze of Opportunities and Challenges
- (2015) Chi-Ping Day et al. CELL
- Expression and role of V1A subunit of V-ATPases in gastric cancer cells
- (2015) Pengfei Liu et al. International Journal of Clinical Oncology
- Recent Insights into the Structure, Regulation, and Function of the V-ATPases
- (2015) Kristina Cotter et al. TRENDS IN BIOCHEMICAL SCIENCES
- Bafilomycin A1 inhibits the growth and metastatic potential of the BEL-7402 liver cancer and HO-8910 ovarian cancer cell lines and induces alterations in their microRNA expression
- (2015) XIAODONG LU et al. Experimental and Therapeutic Medicine
- Anti-leukemic effects of the V-ATPase inhibitor Archazolid A
- (2015) Siwei Zhang et al. Oncotarget
- Vacuolar ATPase 'a2' isoform exhibits distinct cell surface accumulation and modulates matrix metalloproteinase activity in ovarian cancer
- (2015) Arpita Kulshrestha et al. Oncotarget
- CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in neurodevelopment
- (2015) Ping Wang et al. Molecular Autism
- The Lysosomal v-ATPase-Ragulator Complex Is a Common Activator for AMPK and mTORC1, Acting as a Switch between Catabolism and Anabolism
- (2014) Chen-Song Zhang et al. Cell Metabolism
- Activity of Plasma Membrane V-ATPases Is Critical for the Invasion of MDA-MB231 Breast Cancer Cells
- (2014) Kristina Cotter et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- V-ATPase Inhibition Regulates Anoikis Resistance and Metastasis of Cancer Cells
- (2014) C. M. Schempp et al. MOLECULAR CANCER THERAPEUTICS
- Atp6v1c1 May Regulate Filament Actin Arrangement in Breast Cancer Cells
- (2014) Shengmei Feng et al. PLoS One
- V-ATPase is a candidate therapeutic target for Ewing sarcoma
- (2013) Sofia Avnet et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Cathepsin B as a cancer target
- (2013) Christopher S Gondi et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Silencing of Atp6v1c1 Prevents Breast Cancer Growth and Bone Metastasis
- (2013) Shengmei Feng et al. International Journal of Biological Sciences
- Vacuolar H+ ATPase expression and activity is required for Rab27B-dependent invasive growth and metastasis of breast cancer
- (2013) An Hendrix et al. INTERNATIONAL JOURNAL OF CANCER
- The Function of Vacuolar ATPase (V-ATPase) a Subunit Isoforms in Invasiveness of MCF10a and MCF10CA1a Human Breast Cancer Cells
- (2013) Joseph Capecci et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Innate and adaptive immune cells in the tumor microenvironment
- (2013) Thomas F Gajewski et al. NATURE IMMUNOLOGY
- Genome engineering using the CRISPR-Cas9 system
- (2013) F Ann Ran et al. Nature Protocols
- Regulation of Luminal Acidification by the V-ATPase
- (2013) Sylvie Breton et al. PHYSIOLOGY
- The V-ATPase-Inhibitor Archazolid Abrogates Tumor Metastasis via Inhibition of Endocytic Activation of the Rho-GTPase Rac1
- (2012) R. M. Wiedmann et al. CANCER RESEARCH
- Cathepsin B Inhibition Limits Bone Metastasis in Breast Cancer
- (2012) N. P. Withana et al. CANCER RESEARCH
- Expression and functional role of vacuolar H+-ATPase in human hepatocellular carcinoma
- (2012) J. Xu et al. CARCINOGENESIS
- Targeting Reversible Disassembly as a Mechanism of Controlling V-ATPase Activity
- (2012) Patricia M. Kane CURRENT PROTEIN & PEPTIDE SCIENCE
- The renal v-ATPase a4 subunit is expressed in specific subtypes of human gliomas
- (2012) Vincent Gleize et al. GLIA
- Inhibitors of vacuolar ATPase proton pumps inhibit human prostate cancer cell invasion and prostate-specific antigen expression and secretion
- (2012) Vera Michel et al. INTERNATIONAL JOURNAL OF CANCER
- Immunohistochemical localization of C1 subunit of V-ATPase (ATPase C1) in oral squamous cell cancer and normal oral mucosa
- (2011) A García-García et al. BIOTECHNIC & HISTOCHEMISTRY
- Tumor Metastasis: Molecular Insights and Evolving Paradigms
- (2011) Scott Valastyan et al. CELL
- Generation of Chicken Monoclonal Antibodies Against the a1, a2, and a3 Subunit Isoforms of Vacuolar-type Proton ATPase
- (2011) Ge-Hong Sun-Wada et al. HYBRIDOMA
- The vacuolar-ATPase modulates matrix metalloproteinase isoforms in human pancreatic cancer
- (2011) Chuhan Chung et al. LABORATORY INVESTIGATION
- The a3 Isoform Vacuolar Type H+-ATPase Promotes Distant Metastasis in the Mouse B16 Melanoma Cells
- (2011) T. Nishisho et al. MOLECULAR CANCER RESEARCH
- mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H+-ATPase
- (2011) R. Zoncu et al. SCIENCE
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- (2011) C. L. Chaffer et al. SCIENCE
- Measurement of ATP6V1C1 expression in brush cytology samples as a diagnostic and prognostic marker in oral squamous cell carcinoma
- (2010) Mario Pérez-Sayáns et al. CANCER BIOLOGY & THERAPY
- Targeting MMP-9, uPAR and cathepsin B inhibits invasion, migration and activates apoptosis in prostate cancer cells
- (2010) A K Nalla et al. CANCER GENE THERAPY
- Influenza A virus-induced early activation of ERK and PI3K mediates V-ATPase-dependent intracellular pH change required for fusion
- (2010) Henju Marjuki et al. CELLULAR MICROBIOLOGY
- Function of a Subunit Isoforms of the V-ATPase in pH Homeostasis andin VitroInvasion of MDA-MB231 Human Breast Cancer Cells
- (2009) Ayana Hinton et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Imagable 4T1 model for the study of late stage breast cancer
- (2008) Kai Tao et al. BMC CANCER
- Biochemical and functional characterization of the actin-binding activity of the B subunit of yeast vacuolar H+-ATPase
- (2008) J. Zuo et al. JOURNAL OF EXPERIMENTAL BIOLOGY
- Intracellular pH regulation in oral squamous cell carcinoma is mediated by increased V-ATPase activity via over-expression of the ATP6V1C1 gene
- (2007) Eva María Otero-Rey et al. ORAL ONCOLOGY
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