Metformin in contrast to berberine reversed arsenic‐induced oxidative stress in mitochondria from rat pancreas probably via Sirt3‐dependent pathway

Mitochondrial SIRT3 and neurodegenerative brain disorders

(2017) Anamika et al.   JOURNAL OF CHEMICAL NEUROANATOMY

Ellagic acid protects against arsenic toxicity in isolated rat mitochondria possibly through the maintaining of complex II

(2016) E Keshtzar et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Diet and exercise signals regulate SIRT3 and activate AMPK and PGC-1α in skeletal muscle

(2016) Orsolya M. Palacios et al.   Aging-US

Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy

(2016) Angela V. Hafner et al.   Aging-US

SIRT3-SOD2-mROS-dependent autophagy in cadmium-induced hepatotoxicity and salvage by melatonin

(2015) Huifeng Pi et al.   Autophagy

Mitochondrial succinate dehydrogenase is involved in stimulus-secretion coupling and endogenous ROS formation in murine beta cells

(2015) Armin Edalat et al.   DIABETOLOGIA

Skeletal muscle Sirt3 expression and mitochondrial respiration are regulated by a prenatal low-protein diet

(2015) Kate J. Claycombe et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

SIRT3 Overexpression Attenuates Palmitate-Induced Pancreatic β-Cell Dysfunction

(2015) Min Kim et al.   PLoS One

Mitochondrial hyperpolarization during chronic complex I inhibition is sustained by low activity of complex II, III, IV and V

(2014) Marleen Forkink et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

The potential effect of berberine in mercury-induced hepatorenal toxicity in albino rats

(2014) Mohamed S. Othman et al.   FOOD AND CHEMICAL TOXICOLOGY

High fat diet aggravates arsenic induced oxidative stress in rat heart and liver

(2014) Mousumi Dutta et al.   FOOD AND CHEMICAL TOXICOLOGY

Induction of glutathione synthesis in human hepatocytes by acute and chronic arsenic exposure: Differential roles of mitogen-activated protein kinases

(2014) Yongyong Hou et al.   TOXICOLOGY

Arsenic exposure disrupts epigenetic regulation of SIRT1 in human keratinocytes

(2014) Katharine J. Herbert et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Arsenic induces diabetic effects through beta-cell dysfunction and increased gluconeogenesis in mice

(2014) Su Liu et al.   Scientific Reports

Sirtuin 3 regulates mouse pancreatic beta cell function and is suppressed in pancreatic islets isolated from human type 2 diabetic patients

(2013) P. W. Caton et al.   DIABETOLOGIA

Antioxidant, Analgesic, Anti-Inflammatory, and Hepatoprotective Effects of the Ethanol Extract of Mahonia oiwakensis Stem

(2013) Jung Chao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Berberine reverts hepatic mitochondrial dysfunction in high-fat fed rats: A possible role for SirT3 activation

(2013) João Soeiro Teodoro et al.   MITOCHONDRION

Swimming Training Induces Liver Mitochondrial Adaptations to Oxidative Stress in Rats Submitted to Repeated Exhaustive Swimming Bouts

(2013) Frederico D. Lima et al.   PLoS One

Arsenic induces reactive oxygen species-caused neuronal cell apoptosis through JNK/ERK-mediated mitochondria-dependent and GRP 78/CHOP-regulated pathways

(2013) Tien-Hui Lu et al.   TOXICOLOGY LETTERS

Metformin Reduces Endogenous Reactive Oxygen Species and Associated DNA Damage

(2012) C. Algire et al.   Cancer Prevention Research

SIRT3 regulation of mitochondrial oxidative stress

(2012) Alexandra S. Bause et al.   EXPERIMENTAL GERONTOLOGY

Seven sirtuins for seven deadly diseases ofaging

(2012) Brian J. Morris   FREE RADICAL BIOLOGY AND MEDICINE

SIRT3 Protein Deacetylates Isocitrate Dehydrogenase 2 (IDH2) and Regulates Mitochondrial Redox Status

(2012) Wei Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Physiological Roles of Mitochondrial Reactive Oxygen Species

(2012) Laura A. Sena et al.   MOLECULAR CELL

Metformin Reduces Hepatic Expression of SIRT3, the Mitochondrial Deacetylase Controlling Energy Metabolism

(2012) Marcin Buler et al.   PLoS One

Methylated trivalent arsenicals are potent inhibitors of glucose stimulated insulin secretion by murine pancreatic islets

(2012) Christelle Douillet et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Mitochondrial dysfunction in pancreatic β cells

(2012) Sachin Supale et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Metabolic regulation by SIRT3: implications for tumorigenesis

(2012) Lydia W.S. Finley et al.   TRENDS IN MOLECULAR MEDICINE

Muscle or liver-specific Sirt3 deficiency induces hyperacetylation of mitochondrial proteins without affecting global metabolic homeostasis

(2012) Pablo J. Fernandez-Marcos et al.   Scientific Reports

Berberine protects against high fat diet-induced dysfunction in muscle mitochondria by inducing SIRT1-dependent mitochondrial biogenesis

(2011) Ana P. Gomes et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

SIRT3 and cancer: Tumor promoter or suppressor?

(2011) Turki Y. Alhazzazi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Cellular and molecular mechanisms of metformin: an overview

(2011) Benoit Viollet et al.   CLINICAL SCIENCE

Characterization of the Impaired Glucose Homeostasis Produced in C57BL/6 Mice by Chronic Exposure to Arsenic and High-Fat Diet

(2011) David S. Paul et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Arsenic-induced oxidative stress and its reversibility

(2011) Swaran J.S. Flora   FREE RADICAL BIOLOGY AND MEDICINE

Regulation and protection of mitochondrial physiology by sirtuins

(2011) Claudia V. Pereira et al.   MITOCHONDRION

Sirt3 Promotes the Urea Cycle and Fatty Acid Oxidation during Dietary Restriction

(2011) William C. Hallows et al.   MOLECULAR CELL

Mitochondrial SIRT3: A New Potential Therapeutic Target for Metabolic Syndrome

(2011) Jun Yoshino et al.   MOLECULAR CELL

The SirT3 Divining Rod Points to Oxidative Stress

(2011) Eric L. Bell et al.   MOLECULAR CELL

SIRT3 Deficiency and Mitochondrial Protein Hyperacetylation Accelerate the Development of the Metabolic Syndrome

(2011) Matthew D. Hirschey et al.   MOLECULAR CELL

Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production

(2011) E. Jing et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MiADMSA reverses impaired mitochondrial energy metabolism and neuronal apoptotic cell death after arsenic exposure in rats

(2011) Nidhi Dwivedi et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Metformin reduces intracellular reactive oxygen species levels by upregulating expression of the antioxidant thioredoxin via the AMPK-FOXO3 pathway

(2010) Xinguo Hou et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Sirt3 Mediates Reduction of Oxidative Damage and Prevention of Age-Related Hearing Loss under Caloric Restriction

(2010) Shinichi Someya et al.   CELL

Calorie Restriction Reduces Oxidative Stress by SIRT3-Mediated SOD2 Activation

(2010) Xiaolei Qiu et al.   Cell Metabolism

Oxidative stress, insulin signaling, and diabetes

(2010) Justin L. Rains et al.   FREE RADICAL BIOLOGY AND MEDICINE

Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state

(2010) Marc Foretz et al.   JOURNAL OF CLINICAL INVESTIGATION

Sirt3-Mediated Deacetylation of Evolutionarily Conserved Lysine 122 Regulates MnSOD Activity in Response to Stress

(2010) Randa Tao et al.   MOLECULAR CELL

Sirtuin 3, a New Target of PGC-1α, Plays an Important Role in the Suppression of ROS and Mitochondrial Biogenesis

(2010) Xingxing Kong et al.   PLoS One

Arsenic induces pancreatic β-cell apoptosis via the oxidative stress-regulated mitochondria-dependent and endoplasmic reticulum stress-triggered signaling pathways

(2010) Tien-Hui Lu et al.   TOXICOLOGY LETTERS

Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling

(2010) Eric Verdin et al.   TRENDS IN BIOCHEMICAL SCIENCES

Heavy metals, islet function and diabetes development

(2010) Ya Wen Chen et al.   Islets

Mitochondrial Glutathione, a Key Survival Antioxidant

(2009) Montserrat Marí et al.   ANTIOXIDANTS & REDOX SIGNALING

Reactive oxygen species generation and expression of DNA repair-related genes after copper exposure in zebrafish (Danio rerio) ZFL cells

(2009) Juliana Zomer Sandrini et al.   AQUATIC TOXICOLOGY

Synthesis and biological evaluation of berberine analogues as novel up-regulators for both low-density-lipoprotein receptor and insulin receptor

(2009) Yan-Xiang Wang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Protective effect of berberine on beta cells in streptozotocin- and high-carbohydrate/high-fat diet-induced diabetic rats

(2009) Jiyin Zhou et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Berberine lowers blood glucose in type 2 diabetes mellitus patients through increasing insulin receptor expression

(2009) Hao Zhang et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Ascorbic acid combats arsenic-induced oxidative stress in mice liver

(2008) Pathikrit Banerjee et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Nanoencapsulation of quercetin enhances its dietary efficacy in combating arsenic-induced oxidative damage in liver and brain of rats

(2008) Aparajita Ghosh et al.   LIFE SCIENCES

Efficacy of berberine in patients with type 2 diabetes mellitus

(2008) Jun Yin et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Berberine reduces insulin resistance through protein kinase C–dependent up-regulation of insulin receptor expression

(2008) Wei-Jia Kong et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Biomarkers of oxidative stress and damage in human populations exposed to arsenic

(2008) Andrea De Vizcaya-Ruiz et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis

(2008) B.-H. Ahn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arsenic-induced mitochondrial instability leading to programmed cell death in the exposed individuals

(2008) Nilanjana Banerjee et al.   TOXICOLOGY

Dithiothreitol abrogates the effect of arsenic trioxide on normal rat liver mitochondria and human hepatocellular carcinoma cells

(2007) Manash K. Paul et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY