LPS-Binding Protein Modulates Acute Renal Fibrosis by Inducing Pericyte-to-Myofibroblast Trans-Differentiation through TLR-4 Signaling

Presentation matters: Impact of association of amphiphilic LPS with serum carrier proteins on innate immune signaling

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Complement Activation During Ischemia/Reperfusion Injury Induces Pericyte-to-Myofibroblast Transdifferentiation Regulating Peritubular Capillary Lumen Reduction Through pERK Signaling

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Toll-like receptor-4 deficiency alleviates chronic intermittent hypoxia-induced renal injury, inflammation, and fibrosis

(2018) Yan Zhang et al.   Sleep and Breathing

TGFβ signaling and the control of myofibroblast differentiation: Implications for chronic inflammatory disorders

(2017) Jonathon M. Carthy   JOURNAL OF CELLULAR PHYSIOLOGY

Novel Mechanism of the Pericyte-Myofibroblast Transition in Renal Interstitial Fibrosis: Core Fucosylation Regulation

(2017) Nan Wang et al.   Scientific Reports

Toll-Like Receptor-4 Signaling Drives Persistent Fibroblast Activation and Prevents Fibrosis Resolution in Scleroderma

(2017) Swati Bhattacharyya et al.   Advances in Wound Care

Sepsis-induced acute kidney injury

(2016) Hernando Gómez et al.   Current Opinion in Critical Care

Role of mesenchymal stem cells in kidney injury and fibrosis

(2016) Christoph Kuppe et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Pericyte MyD88 and IRAK4 control inflammatory and fibrotic responses to tissue injury

(2016) Irina A. Leaf et al.   JOURNAL OF CLINICAL INVESTIGATION

Emerging role of Lipopolysaccharide binding protein in sepsis-induced acute kidney injury

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Perivascular Gli1+ Progenitors Are Key Contributors to Injury-Induced Organ Fibrosis

(2015) Rafael Kramann et al.   Cell Stem Cell

Sepsis-induced acute kidney injury revisited

(2014) Alexander Zarbock et al.   Current Opinion in Critical Care

Crosstalk between TGF-β1 and complement activation augments epithelial injury in pulmonary fibrosis

(2014) Hongmei Gu et al.   FASEB JOURNAL

Endothelin-1 and its role in the pathogenesis of infectious diseases

(2014) Brandi D. Freeman et al.   LIFE SCIENCES

The profibrotic role of endothelin-1: Is the door still open for the treatment of fibrotic diseases?

(2014) Fernando Rodríguez-Pascual et al.   LIFE SCIENCES

Biomarkers of endothelial activation/dysfunction in infectious diseases

(2013) Andrea V Page et al.   Virulence

Renal pericytes: regulators of medullary blood flow

(2012) T. M. Kennedy-Lydon et al.   Acta Physiologica

Toll-Like Receptor 4 Signaling Augments Transforming Growth Factor-β Responses

(2012) Swati Bhattacharyya et al.   AMERICAN JOURNAL OF PATHOLOGY

Transforming Growth Factor β-1 Stimulates Profibrotic Epithelial Signaling to Activate Pericyte-Myofibroblast Transition in Obstructive Kidney Fibrosis

(2012) Ching-Fang Wu et al.   AMERICAN JOURNAL OF PATHOLOGY

Sepsis-induced acute respiratory distress syndrome with fatal outcome is associated to increased serum transforming growth factor beta-1 levels

(2011) Raúl de Pablo et al.   European Journal of Internal Medicine

PGC-1α promotes recovery after acute kidney injury during systemic inflammation in mice

(2011) Mei Tran et al.   JOURNAL OF CLINICAL INVESTIGATION

Cellular pathophysiology of ischemic acute kidney injury

(2011) Joseph V. Bonventre et al.   JOURNAL OF CLINICAL INVESTIGATION

Platelet-derived growth factor receptor signaling activates pericyte–myofibroblast transition in obstructive and post-ischemic kidney fibrosis

(2011) Yi-Ting Chen et al.   KIDNEY INTERNATIONAL

Disruption of Smad4 impairs TGF-β/Smad3 and Smad7 transcriptional regulation during renal inflammation and fibrosis in vivo and in vitro

(2011) Xiao-Ming Meng et al.   KIDNEY INTERNATIONAL

The origin of interstitial myofibroblasts in chronic kidney disease

(2011) Ivica Grgic et al.   PEDIATRIC NEPHROLOGY

Broken Barriers: A New Take on Sepsis Pathogenesis

(2011) N. M. Goldenberg et al.   Science Translational Medicine

Exploring the LPS/TLR4 signal pathway with small molecules

(2010) Francesco Peri et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Immunomodulation in the critically ill

(2009) N.R. Webster et al.   BRITISH JOURNAL OF ANAESTHESIA

Toll-Like Receptor 4: A Novel Signaling Pathway During Renal Fibrogenesis

(2009) Matthew T. Campbell et al.   JOURNAL OF SURGICAL RESEARCH

Serum Lipopolysaccharide Binding Protein Levels Predict Severity of Lung Injury and Mortality in Patients with Severe Sepsis

(2009) Jesús Villar et al.   PLoS One

Pericytes and Perivascular Fibroblasts Are the Primary Source of Collagen-Producing Cells in Obstructive Fibrosis of the Kidney

(2008) Shuei-Liong Lin et al.   AMERICAN JOURNAL OF PATHOLOGY

Roles for LPS-dependent interaction and relocation of TLR4 and TRAM in TRIF-signaling

(2008) Natsuko Tanimura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

LPS/TLR4 signal transduction pathway

(2008) Yong-Chen Lu et al.   CYTOKINE

Septic Acute Kidney Injury: New Concepts

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