Potential Benefits of Nobiletin, A Citrus Flavonoid, against Alzheimer’s Disease and Parkinson’s Disease
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Title
Potential Benefits of Nobiletin, A Citrus Flavonoid, against Alzheimer’s Disease and Parkinson’s Disease
Authors
Keywords
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Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 20, Issue 14, Pages 3380
Publisher
MDPI AG
Online
2019-07-10
DOI
10.3390/ijms20143380
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Note: Only part of the references are listed.- Inflammatory mechanisms in neurodegeneration
- (2019) Michael R. Nichols et al. JOURNAL OF NEUROCHEMISTRY
- Novel Approaches for the Treatment of Alzheimer’s and Parkinson’s Disease
- (2019) Michiel Van Bulck et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Novel pathways in the treatment of Major Depression: focus on the glutamatergic system
- (2019) Carmine Tomasetti et al. CURRENT PHARMACEUTICAL DESIGN
- Nobiletin Protects against Systemic Inflammation-Stimulated Memory Impairment via MAPK and NF-κB Signaling Pathways
- (2019) Guoyuan Qi et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Three Polymethoxyflavones Purified from Ougan (Citrus reticulata Cv. Suavissima) Inhibited LPS-Induced NO Elevation in the Neuroglia BV-2 Cell Line via the JAK2/STAT3 Pathway
- (2019) Yue Wang et al. Nutrients
- Nobiletin Reduces Intracellular and Extracellular β-Amyloid in iPS Cell-Derived Alzheimer’s Disease Model Neurons
- (2018) Junko Kimura et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Synthetic Fragment of Receptor for Advanced Glycation End Products Prevents Memory Loss and Protects Brain Neurons in Olfactory Bulbectomized Mice
- (2018) Olga M. Volpina et al. JOURNAL OF ALZHEIMERS DISEASE
- Eradicating Suicide at Its Roots: Preclinical Bases and Clinical Evidence of the Efficacy of Ketamine in the Treatment of Suicidal Behaviors
- (2018) Domenico De Berardis et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Global, regional, and national burden of Parkinson's disease, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
- (2018) E. Ray Dorsey et al. LANCET NEUROLOGY
- Neurodegenerative signaling factors and mechanisms in Parkinson's pathology
- (2017) Poonam Goswami et al. TOXICOLOGY IN VITRO
- Polymethoxyflavones: Novel β-Secretase (BACE1) Inhibitors from Citrus Peels
- (2017) Kumju Youn et al. Nutrients
- Nobiletin promotes antioxidant and anti-inflammatory responses and elicits protection against ischemic stroke in vivo
- (2016) Lan Zhang et al. BRAIN RESEARCH
- Nerve growth factor enhances the CRE-dependent transcriptional activity activated by nobiletin in PC12 cells
- (2016) Jiro Takito et al. CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
- The amyloid hypothesis of Alzheimer's disease at 25 years
- (2016) Dennis J Selkoe et al. EMBO Molecular Medicine
- Neuroprotective and Therapeutic Strategies against Parkinson’s Disease: Recent Perspectives
- (2016) Sumit Sarkar et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Nobiletin, a citrus flavonoid, improves cognitive impairment and reduces soluble Aβ levels in a triple transgenic mouse model of Alzheimer's disease (3XTg-AD)
- (2015) Akira Nakajima et al. BEHAVIOURAL BRAIN RESEARCH
- Nobiletin Protects Dopaminergic Neurons in the 1-Methyl-4-Phenylpyridinium-Treated Rat Model of Parkinson's Disease
- (2015) Kyoung Hoon Jeong et al. JOURNAL OF MEDICINAL FOOD
- Parkinson's disease
- (2015) Lorraine V Kalia et al. LANCET
- Neuroprotective effect of Citrus unshiu immature peel and nobiletin inhibiting hydrogen peroxide-induced oxidative stress in HT22 murine hippocampal neuronal cells
- (2015) InYoung Choi et al. Pharmacognosy Magazine
- Cognitive and emotional profiles of aged Alzheimer's disease (3×TgAD) mice: Effects of environmental enrichment and sexual dimorphism
- (2014) Gloria Blázquez et al. BEHAVIOURAL BRAIN RESEARCH
- Upregulation of N-Methyl-D-aspartate Receptor Subunits and c-Fos Expressing Genes in PC12D Cells by Nobiletin
- (2014) Junko Kimura et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Neuroprotective effect of nobiletin on cerebral ischemia–reperfusion injury in transient middle cerebral artery-occluded rats
- (2014) Nodoka Yasuda et al. BRAIN RESEARCH
- Nobiletin, a flavone from Citrus depressa, induces gene expression and increases the protein level and activity of neprilysin in SK-N-SH cells
- (2014) Hironori Fujiwara et al. CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
- Hesperidin, nobiletin, and tangeretin are collectively responsible for the anti-neuroinflammatory capacity of tangerine peel (Citri reticulatae pericarpium)
- (2014) Su-Chen Ho et al. FOOD AND CHEMICAL TOXICOLOGY
- Function, therapeutic potential and cell biology of BACE proteases: current status and future prospects
- (2014) Robert Vassar et al. JOURNAL OF NEUROCHEMISTRY
- Nobiletin, a citrus flavonoid, ameliorates cognitive impairment, oxidative burden, and hyperphosphorylation of tau in senescence-accelerated mouse
- (2013) Akira Nakajima et al. BEHAVIOURAL BRAIN RESEARCH
- Characteristics of nobiletin-mediated alteration of gene expression in cultured cell lines
- (2013) Kiyomitsu Nemoto et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- 6-Demethoxynobiletin, a Nobiletin-Analog Citrus Flavonoid, Enhances Extracellular Signal-Regulated Kinase Phosphorylation in PC12D Cells
- (2013) Junko Kimura et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Nobiletin protects against cerebral ischemia via activating the p-Akt, p-CREB, BDNF and Bcl-2 pathway and ameliorating BBB permeability in rat
- (2013) Lan Zhang et al. BRAIN RESEARCH BULLETIN
- Nobiletin-richCitrus reticulatapeels, a kampo medicine for Alzheimer's disease: A case series
- (2013) Takashi Seki et al. Geriatrics & Gerontology International
- Nobiletin treatment improves motor and cognitive deficits seen in MPTP-induced Parkinson model mice
- (2013) Y. Yabuki et al. NEUROSCIENCE
- Suppressive effect of nobiletin, a citrus polymethoxyflavonoid that downregulates thioredoxin-interacting protein expression, on tunicamycin-induced apoptosis in SK-N-SH human neuroblastoma cells
- (2013) Ayaka Ikeda et al. NEUROSCIENCE LETTERS
- Cognitive and non-cognitive behaviors in the triple transgenic mouse model of Alzheimer's disease expressing mutated APP, PS1, and Mapt (3xTg-AD)
- (2012) Mohammed Filali et al. BEHAVIOURAL BRAIN RESEARCH
- NMDA Neurotransmission Dysfunction in Behavioral and Psychological Symptoms of Alzheimer's Disease
- (2012) Yu-Jhen Huang et al. Current Neuropharmacology
- The molecular biology of memory: cAMP, PKA, CRE, CREB-1, CREB-2, and CPEB
- (2012) Eric R Kandel Molecular Brain
- Nobiletin suppresses adipocyte differentiation of 3T3-L1 cells by an insulin and IBMX mixture induction
- (2011) Kota Kanda et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Animal models in the drug discovery pipeline for Alzheimer's disease
- (2011) Debby Van Dam et al. BRITISH JOURNAL OF PHARMACOLOGY
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- (2011) E. E. Mulvihill et al. DIABETES
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- (2011) Jeng-Dian Su et al. FREE RADICAL BIOLOGY AND MEDICINE
- Nobiletin Suppresses Adipogenesis by Regulating the Expression of Adipogenic Transcription Factors and the Activation of AMP-Activated Protein Kinase (AMPK)
- (2011) Youngmin Choi et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Nobiletin, a polymethoxylated flavonoid from citrus, shows anti-angiogenic activity in a zebrafish in vivo model and HUVEC in vitro model
- (2011) Kai Heng Lam et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- A novel glycogen synthase kinase-3 inhibitor 2-methyl-5-(3-{4-[(S )-methylsulfinyl]phenyl}-1-benzofuran-5-yl)-1,3,4-oxadiazole decreases tau phosphorylation and ameliorates cognitive deficits in a transgenic model of Alzheimer’s disease
- (2011) Tomohiro Onishi et al. JOURNAL OF NEUROCHEMISTRY
- Nobiletin improves hyperglycemia and insulin resistance in obese diabetic ob/ob mice
- (2010) Young-Sil Lee et al. BIOCHEMICAL PHARMACOLOGY
- Anti-neuroinflammatory Activity of Nobiletin on Suppression of Microglial Activation
- (2010) Yanji Cui et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Expression and functional profiling of neprilysin, insulin-degrading enzyme, and endothelin-converting enzyme in prospectively studied elderly and Alzheimer’s brain
- (2010) Suqing Wang et al. JOURNAL OF NEUROCHEMISTRY
- Nobiletin, a citrus flavonoid, suppresses invasion and migration involving FAK/PI3K/Akt and small GTPase signals in human gastric adenocarcinoma AGS cells
- (2010) Yi-Chieh Lee et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders
- (2010) Giles E. Hardingham et al. NATURE REVIEWS NEUROSCIENCE
- Protective effects of the citrus flavanones to PC12 cells against cytotoxicity induced by hydrogen peroxide
- (2010) Yan-hua Lu et al. NEUROSCIENCE LETTERS
- 4′-Demethylnobiletin, a Bioactive Metabolite of Nobiletin Enhancing PKA/ERK/CREB Signaling, Rescues Learning Impairment Associated with NMDA Receptor Antagonism via Stimulation of the ERK Cascade
- (2009) Md. Al Rahim et al. BIOCHEMISTRY
- Nobiletin improves brain ischemia-induced learning and memory deficits through stimulation of CaMKII and CREB phosphorylation
- (2009) Yui Yamamoto et al. BRAIN RESEARCH
- Neurochemistry, Neuropathology, and Heredity in SAMP8: A Mouse Model of Senescence
- (2009) Koji Tomobe et al. NEUROCHEMICAL RESEARCH
- Age-dependent phenotypic characteristics of a triple transgenic mouse model of Alzheimer disease.
- (2008) Susanna Pietropaolo et al. BEHAVIORAL NEUROSCIENCE
- Sp1 is an essential transcription factor for LPS-induced tissue factor expression in THP-1 monocytic cells, and nobiletin represses the expression through inhibition of NF-κB, AP-1, and Sp1 activation
- (2008) Yuki Hirata et al. BIOCHEMICAL PHARMACOLOGY
- Detailed immunohistochemical characterization of temporal and spatial progression of Alzheimer's disease-related pathologies in male triple-transgenic mice
- (2008) Michael A Mastrangelo et al. BMC NEUROSCIENCE
- Suppressive effects of nobiletin on hyperleptinemia and colitis-related colon carcinogenesis in male ICR mice
- (2008) Shingo Miyamoto et al. CARCINOGENESIS
- Nobiletin, a Citrus Flavonoid, Improves Memory Impairment and A Pathology in a Transgenic Mouse Model of Alzheimer's Disease
- (2008) H. Onozuka et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Nobiletin, a citrus flavonoid with neurotrophic action, augments protein kinase A-mediated phosphorylation of the AMPA receptor subunit, GluR1, and the postsynaptic receptor response to glutamate in murine hippocampus
- (2007) Kentaro Matsuzaki et al. EUROPEAN JOURNAL OF PHARMACOLOGY
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