Laminar Flow Activation of ERK5 Protein in Vascular Endothelium Leads to Atheroprotective Effect via NF-E2-related Factor 2 (Nrf2) Activation

CYLD negatively regulates transforming growth factor-β-signalling via deubiquitinating Akt

(2012) Jae Hyang Lim et al.   Nature Communications

Endogenous Vascular Endothelial Growth Factor-A (VEGF-A) Maintains Endothelial Cell Homeostasis by Regulating VEGF Receptor-2 Transcription

(2011) Guangqi E et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oscillatory Shear Stress Induces Mitochondrial Superoxide Production: Implication of NADPH Oxidase and c-Jun NH2-Terminal Kinase Signaling

(2010) Wakako Takabe et al.   ANTIOXIDANTS & REDOX SIGNALING

Piceatannol induces heme oxygenase-1 expression in human mammary epithelial cells through activation of ARE-driven Nrf2 signaling

(2010) Hyun-Hee Lee et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

PKC  decreases eNOS protein stability via inhibitory phosphorylation of ERK5

(2010) P. Nigro et al.   BLOOD

Erk5 Activation Elicits a Vasoprotective Endothelial Phenotype via Induction of Krüppel-like Factor 4 (KLF4)

(2010) Nils Ohnesorge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MEK5 is Activated by Shear Stress, Activates ERK5 and Induces KLF4 to Modulate TNF Responses in Human Dermal Microvascular Endothelial Cells

(2010) PAUL R. CLARK et al.   MICROCIRCULATION

The rise of antioxidant signaling—The evolution and hormetic actions of Nrf2

(2010) Jonathan Maher et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Flow Activation of AMP-Activated Protein Kinase in Vascular Endothelium Leads to Krüppel-Like Factor 2 Expression

(2009) Angela Young et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Activation of Nrf2 in Endothelial Cells Protects Arteries From Exhibiting a Proinflammatory State

(2009) Mustafa Zakkar et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Induction of the Cytoprotective Enzyme Heme Oxygenase-1 by Statins Is Enhanced in Vascular Endothelium Exposed to Laminar Shear Stress and Impaired by Disturbed Flow

(2009) Faisal Ali et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of Nrf2 at Multiple Sites by MAP Kinases Has a Limited Contribution in Modulating the Nrf2-Dependent Antioxidant Response

(2009) Zheng Sun et al.   PLoS One

Extracellular Signal-Regulated Kinase 5 SUMOylation Antagonizes Shear Stress–Induced Antiinflammatory Response and Endothelial Nitric Oxide Synthase Expression in Endothelial Cells

(2008) Chang-Hoon Woo et al.   CIRCULATION RESEARCH

Nrf2 signaling: An adaptive response pathway for protection against environmental toxic insults

(2007) W OSBURN et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH