Translation Control of HAC1 by Regulation of Splicing in Saccharomyces cerevisiae

RNA-Seq approach for accurate characterization of splicing efficiency of yeast introns

(2019) Xuhua Xia   METHODS

Global Proteome Remodeling during ER Stress Involves Hac1-Driven Expression of Long Undecoded Transcript Isoforms

(2018) Kelsey Marie Van Dalfsen et al.   DEVELOPMENTAL CELL

DAMBE7: New and Improved Tools for Data Analysis in Molecular Biology and Evolution

(2018) Xuhua Xia   MOLECULAR BIOLOGY AND EVOLUTION

Engineering ER-stress dependent non-conventional mRNA splicing

(2018) Weihan Li et al.   eLife

The Unfolded Protein Response Pathway in the Yeast Kluyveromyces lactis. A Comparative View among Yeast Species

(2018) Mariana Hernández-Elvira et al.   Cells

Identification of an Exceptionally Long Intron in the HAC1 Gene of Candida parapsilosis

(2018) Elise Iracane et al.   mSphere

Acidosis Activates Endoplasmic Reticulum Stress Pathways through GPR4 in Human Vascular Endothelial Cells

(2017) Lixue Dong et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Bypass of Activation Loop Phosphorylation by Aspartate 836 in Activation of the Endoribonuclease Activity of Ire1

(2017) Michael C. Armstrong et al.   MOLECULAR AND CELLULAR BIOLOGY

Nuclear mRNA degradation tunes the gain of the unfolded protein response in Saccharomyces cerevisiae

(2017) Debasish Sarkar et al.   NUCLEIC ACIDS RESEARCH

ARSDA: A New Approach for Storing, Transmitting and Analyzing Transcriptomic Data

(2017) Xuhua Xia   G3-Genes Genomes Genetics

An unfolded protein-induced conformational switch activates mammalian IRE1

(2017) G Elif Karagöz et al.   eLife

Regulated Ire1-dependent mRNA decay requires no-go mRNA degradation to maintain endoplasmic reticulum homeostasis in S. pombe

(2017) Nicholas R Guydosh et al.   eLife

Acetic Acid Causes Endoplasmic Reticulum Stress and Induces the Unfolded Protein Response in Saccharomyces cerevisiae

(2017) Nozomi Kawazoe et al.   Frontiers in Microbiology

The Role of +4U as an Extended Translation Termination Signal in Bacteria

(2016) Yulong Wei et al.   GENETICS

Coevolution between Stop Codon Usage and Release Factors in Bacterial Species

(2016) Yulong Wei et al.   MOLECULAR BIOLOGY AND EVOLUTION

Divergence and Conservation of the Major UPR Branch IRE1-bZIP Signaling Pathway across Eukaryotes

(2016) Lingrui Zhang et al.   Scientific Reports

The fail-safe mechanism of post-transcriptional silencing of unspliced HAC1 mRNA

(2016) Rachael Di Santo et al.   eLife

The Role of +4U as an Extended Translation Termination Signal in Bacteria

(2016) Yulong Wei et al.   GENETICS

The Monoterpene Carvacrol Generates Endoplasmic Reticulum Stress in the Pathogenic Fungus Candida albicans

(2015) Julien Chaillot et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Cytosolic pH of Individual Saccharomyces cerevisiae Cells Is a Key Factor in Acetic Acid Tolerance

(2015) Miguel Fernández-Niño et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

A conformational RNA zipper promotes intron ejection during non-conventional XBP1 mRNA splicing

(2015) J. Peschek et al.   EMBO REPORTS

Evidence That Base-pairing Interaction between Intron and mRNA Leader Sequences Inhibits Initiation ofHAC1mRNA Translation in Yeast

(2015) Leena Sathe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The unfolded protein response: the dawn of a new field

(2015) Kazutoshi MORI   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

The UPR Branch IRE1-bZIP60 in Plants Plays an Essential Role in Viral Infection and Is Complementary to the Only UPR Pathway in Yeast

(2015) Lingrui Zhang et al.   PLoS Genetics

The mammalian tRNA ligase complex mediates splicing ofXBP1mRNA and controls antibody secretion in plasma cells

(2014) Jennifer Jurkin et al.   EMBO JOURNAL

A Novel Role for Protein Kinase Kin2 in RegulatingHAC1mRNA Translocation, Splicing, and Translation

(2014) Ashish Anshu et al.   MOLECULAR AND CELLULAR BIOLOGY

A Synthetic Biology Approach Identifies the Mammalian UPR RNA Ligase RtcB

(2014) Yanyan Lu et al.   MOLECULAR CELL

Specificity in endoplasmic reticulum-stress signaling in yeast entails a step-wise engagement of HAC1 mRNA to clusters of the stress sensor Ire1

(2014) Eelco van Anken et al.   eLife

F-actin and a Type-II Myosin Are Required for Efficient Clustering of the ER Stress Sensor Ire1

(2013) Yuki Ishiwata-Kimata et al.   CELL STRUCTURE AND FUNCTION

Mutual Cross Talk between the Regulators Hac1 of the Unfolded Protein Response and Gcn4 of the General Amino Acid Control of Saccharomyces cerevisiae

(2013) Britta Herzog et al.   EUKARYOTIC CELL

IRE1: ER stress sensor and cell fate executor

(2013) Yani Chen et al.   TRENDS IN CELL BIOLOGY

Ribosome Deficiency Protects Against ER Stress in Saccharomyces cerevisiae

(2012) K. K. Steffen et al.   GENETICS

IRE1  Cleaves Select microRNAs During ER Stress to Derepress Translation of Proapoptotic Caspase-2

(2012) J.-P. Upton et al.   SCIENCE

Bax induces activation of the unfolded protein response by inducing HAC1 mRNA splicing in Saccharomyces cerevisiae

(2012) Birsen Çakir   YEAST

From Cis-Regulatory Elements to Complex RNPs and Back

(2012) F. Gebauer et al.   Cold Spring Harbor Perspectives in Biology

Regulation of mRNA Translation by Signaling Pathways

(2012) P. P. Roux et al.   Cold Spring Harbor Perspectives in Biology

The unfolded protein response in fission yeast modulates stability of select mRNAs to maintain protein homeostasis

(2012) Philipp Kimmig et al.   eLife

Function of yeast and amphioxus tRNA ligase in IRE1alpha-dependent XBP1 mRNA splicing

(2011) Takao Iwawaki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Structural and functional basis for RNA cleavage by Ire1

(2011) Alexei V Korennykh et al.   BMC BIOLOGY

Translation Initiation: A Regulatory Role for Poly(A) Tracts in Front of the AUG Codon inSaccharomyces cerevisiae

(2011) Xuhua Xia et al.   GENETICS

Loss of Subcellular Lipid Transport Due toARV1Deficiency Disrupts Organelle Homeostasis and Activates the Unfolded Protein Response

(2011) Caryn F. Shechtman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Attenuation of yeast UPR is essential for survival and is mediated byIRE1kinase

(2011) Aditi Chawla et al.   JOURNAL OF CELL BIOLOGY

Homeostatic adaptation to endoplasmic reticulum stress depends on Ire1 kinase activity

(2011) Claudia Rubio et al.   JOURNAL OF CELL BIOLOGY

Functional and genomic analyses of blocked protein O-mannosylation in baker's yeast

(2011) Javier Arroyo et al.   MOLECULAR MICROBIOLOGY

Signal transduction by IRE1-mediated splicing of bZIP50 and other stress sensors in the endoplasmic reticulum stress response of rice

(2011) Shimpei Hayashi et al.   PLANT JOURNAL

Conserved RNA structures in the non-canonical Hac1/Xbp1 intron

(2011) Katarzyna B. Hooks et al.   RNA Biology

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

(2011) P. Walter et al.   SCIENCE

Unfolded Proteins Are Ire1-Activating Ligands That Directly Induce the Unfolded Protein Response

(2011) B. M. Gardner et al.   SCIENCE

Endoplasmic reticulum stress-sensing mechanisms in yeast and mammalian cells

(2010) Yukio Kimata et al.   CURRENT OPINION IN CELL BIOLOGY

Extracellular Secretion of Overexpressed Glycosylphosphatidylinositol-Linked Cell Wall Protein Utr2/Crh2p as a Novel Protein Quality Control Mechanism in Saccharomyces cerevisiae

(2010) Kelly A. Miller et al.   EUKARYOTIC CELL

Dual Functions of Yeast tRNA Ligase in the Unfolded Protein Response: Unconventional Cytoplasmic Splicing of HAC1 Pre-mRNA Is Not Sufficient to Release Translational Attenuation

(2010) Takao Mori et al.   MOLECULAR BIOLOGY OF THE CELL

Walking Along the Serendipitous Path of Discovery

(2010) Peter Walter   MOLECULAR BIOLOGY OF THE CELL

Endoplasmic reticulum is a major target of cadmium toxicity in yeast

(2010) Aurélie Gardarin et al.   MOLECULAR MICROBIOLOGY

Functional characterization of the unconventional splicing of Yarrowia lipolytica HAC1 mRNA induced by unfolded protein response

(2010) Mi Hee Oh et al.   YEAST

BiP Binding to the ER-Stress Sensor Ire1 Tunes the Homeostatic Behavior of the Unfolded Protein Response

(2010) David Pincus et al.   PLOS BIOLOGY

4E-BP Extends Lifespan upon Dietary Restriction by Enhancing Mitochondrial Activity in Drosophila

(2009) Brian M. Zid et al.   CELL

IRE1α Kinase Activation Modes Control Alternate Endoribonuclease Outputs to Determine Divergent Cell Fates

(2009) Dan Han et al.   CELL

HacA-Dependent Transcriptional Switch ReleaseshacAmRNA from a Translational Block upon Endoplasmic Reticulum Stress

(2009) Harm J. Mulder et al.   EUKARYOTIC CELL

Regulated Ire1-dependent decay of messenger RNAs in mammalian cells

(2009) Julie Hollien et al.   JOURNAL OF CELL BIOLOGY

Novel insights into the unfolded protein response using Pichia pastoris specific DNA microarrays

(2008) Alexandra Graf et al.   BMC GENOMICS

Transcript-specific translational regulation in the unfolded protein response ofSaccharomyces cerevisiae

(2008) Tom Payne et al.   FEBS LETTERS

The unfolded protein response signals through high-order assembly of Ire1

(2008) Alexei V. Korennykh et al.   NATURE

Messenger RNA targeting to endoplasmic reticulum stress signalling sites

(2008) Tomás Aragón et al.   NATURE