Vaccinations for Colorectal Cancer: Progress, Strategies, and Novel Adjuvants

Colorectal Cancer and Nutrition

(2019) Kannan Thanikachalam et al.   Nutrients

Comparative proteomic study reveals the enhanced immune response with the blockade of interleukin 10 with anti-IL-10 and anti-IL-10 receptor antibodies in human U937 cells

(2019) Guoying Ni et al.   PLoS One

Regulatory T cells: a potential target in cancer immunotherapy

(2018) Kohei Shitara et al.   Annals of the New York Academy of Sciences

Plasticity and intratumoural heterogeneity of cell surface antigen expression in breast cancer

(2018) Ján Remšík et al.   BRITISH JOURNAL OF CANCER

Individualized colorectal cancer screening based on the clinical risk factors: beyond family history of colorectal cancer

(2018) Chan Hyuk Park et al.   GASTROINTESTINAL ENDOSCOPY

In Reply to Yilmaz et al

(2018) Linda Chen et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

MUC1- and Survivin-based DNA Vaccine Combining Immunoadjuvants CpG and interleukin-2 in a Bicistronic Expression Plasmid Generates Specific Immune Responses and Antitumour Effects in a Murine Colorectal Carcinoma Model

(2018) C. Liu et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Role of regulatory T�cells and CD8+�T lymphocytes in the dissemination of circulating tumor cells in primary invasive breast cancer

(2018) Dandan Xue et al.   Oncology Letters

The role of Galectin-3 in modulating tumor growth and immunosuppression within the tumor microenvironment

(2018) Mohammad Farhad et al.   OncoImmunology

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Parapheromones suppress chemotherapy side-effects

(2018) Goeun Lee et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

EGF ligand fused to truncated Pseudomonas�aeruginosa exotoxin�A specifically targets and inhibits EGFR‑positive cancer cells

(2018) Saeed Hashimi et al.   ONCOLOGY REPORTS

Adjuvant effect of the novel TLR1/TLR2 agonist Diprovocim synergizes with anti–PD-L1 to eliminate melanoma in mice

(2018) Ying Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A randomized phase II clinical trial of dendritic cell vaccination following complete resection of colon cancer liver metastasis

(2018) Javier Rodriguez et al.   Journal for ImmunoTherapy of Cancer

Discovery of common and rare genetic risk variants for colorectal cancer

(2018) Jeroen R. Huyghe et al.   NATURE GENETICS

Colorectal cancer vaccines: Tumor-associated antigens vs neoantigens

(2018) Sandra Wagner et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Safety and Outcomes of Combining Immune Checkpoint Inhibitors with Radiation Therapy

(2017) O. Mohamad et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Multicenter Evaluation of the Tolerability of Combined Treatment With PD-1 and CTLA-4 Immune Checkpoint Inhibitors and Palliative Radiation Therapy

(2017) Andrew Bang et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Randomized controlled Phase III study comparing hepatic arterial infusion with systemic chemotherapy after curative resection for liver metastasis of colorectal carcinoma: JFMC 29–0003

(2017) Michitaka Honda et al.   Journal of Cancer Research and Therapeutics

PO-0959: REQUITE: Radiation Induced Lymphocyte Apoptosis assay as a predictor for radiotherapy side effects

(2017) C. Talbot et al.   RADIOTHERAPY AND ONCOLOGY

Graph-based optimization of epitope coverage for vaccine antigen design

(2017) James Theiler et al.   STATISTICS IN MEDICINE

Specific humoral and cellular immune responses in cancer patients undergoing chronic immunization with a VEGF-based therapeutic vaccine

(2017) Yanelys Morera et al.   VACCINE

Investigation of phosphorylated adjuvants co-encapsulated with a model cancer peptide antigen for the treatment of colorectal cancer and liver metastasis

(2017) Tyler J. Goodwin et al.   VACCINE

Vaccine-elicited memory CD4+ T cell expansion is impaired in the lungs during tuberculosis

(2017) Stephen M. Carpenter et al.   PLoS Pathogens

Interferon-α Promotes the Expression of Cancer Stem Cell Markers in Oral Squamous Cell Carcinoma

(2017) Hailong Ma et al.   Journal of Cancer

Synthesis and Evaluation of GM2-Monophosphoryl Lipid A Conjugate as a Fully Synthetic Self-Adjuvant Cancer Vaccine

(2017) Zhifang Zhou et al.   Scientific Reports

Raised interferon-β, type 3 interferon and interferon-stimulated genes - evidence of innate immune activation in neutrophilic asthma

(2016) J. da Silva et al.   CLINICAL AND EXPERIMENTAL ALLERGY

PI3K/Akt/mTOR Signaling and Plasma Membrane Proteins Are Implicated in Responsiveness to Adjuvant Dendritic Cell Vaccination for Metastatic Colorectal Cancer

(2016) David C. Qian et al.   CLINICAL CANCER RESEARCH

Fulminant Myocarditis with Combination Immune Checkpoint Blockade

(2016) Douglas B. Johnson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Investigation the Possibility of Using Peptides with a Helical Repeating Pattern of Hydro-Phobic and Hydrophilic Residues to Inhibit IL-10

(2016) Guoying Ni et al.   PLoS One

Galectin signatures contribute to the heterogeneity of breast cancer and provide new prognostic information and therapeutic targets

(2016) Andrée-Anne Grosset et al.   Oncotarget

Sipuleucel-T (Provenge®)—Autopsy of an Innovative Paradigm Change in Cancer Treatment: Why a Single-Product Biotech Company Failed to Capitalize on its Breakthrough Invention

(2015) Szymon Jarosławski et al.   BIODRUGS

Allogenic dendritic cell and tumor cell fused vaccine for targeted imaging and enhanced immunotherapeutic efficacy of gastric cancer

(2015) Chao Li et al.   BIOMATERIALS

Immune checkpoint blockade in hematologic malignancies

(2015) P. Armand   BLOOD

Development of a potent melanoma vaccine capable of stimulating CD8+ T-cells independently of dendritic cells in a mouse model

(2015) Katie L. Powell et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Manipulating IL-10 signalling blockade for better immunotherapy

(2015) Guoying Ni et al.   CELLULAR IMMUNOLOGY

H5N1 Vaccine–Elicited Memory B Cells Are Genetically Constrained by the IGHV Locus in the Recognition of a Neutralizing Epitope in the Hemagglutinin Stem

(2015) Adam K. Wheatley et al.   JOURNAL OF IMMUNOLOGY

Sequential cancer mutations in cultured human intestinal stem cells

(2015) Jarno Drost et al.   NATURE

A dendritic cell vaccine increases the breadth and diversity of melanoma neoantigen-specific T cells

(2015) B. M. Carreno et al.   SCIENCE

The future of immune checkpoint therapy

(2015) P. Sharma et al.   SCIENCE

Rescue of CD8+ T cell vaccine memory following sublethal γ irradiation

(2015) Hugh I. McFarland et al.   VACCINE

A quantitative analysis of therapeutic cancer vaccines in phase 2 or phase 3 trial

(2015) Amabel CL Tan et al.   Journal for ImmunoTherapy of Cancer

Selective loss of vaccine-specific memory B cells in a rhesus macaque model of chemotherapy: influence of doxorubicin on immunological memory

(2015) H. M. Ingelman-Sundberg et al.   HAEMATOLOGICA

Cytosolic galectin-7 impairs p53 functions and induces chemoresistance in breast cancer cells

(2014) Andrée-Anne Grosset et al.   BMC CANCER

Hepatitis C virus and interferon type III (interferon-λ3/interleukin-28B and interferon-λ4): genetic basis of susceptibility to infection and response to antiviral treatment

(2014) E. Riva et al.   CLINICAL MICROBIOLOGY AND INFECTION

Intracellular galectins in cancer cells: Potential new targets for therapy

(2014) MARIA C. VLADOIU et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Clinical evaluation of systemic and local immune responses in cancer: time for integration

(2013) Dmitriy W. Gutkin et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Inhibiting galectin-1 reduces murine lung metastasis with increased CD4+ and CD8+ T cells and reduced cancer cell adherence

(2012) Koichi Ito et al.   CLINICAL & EXPERIMENTAL METASTASIS

Adjuvants for Enhancing the Immunogenicity of Whole Tumor Cell Vaccines

(2011) Cheryl Lai-Lai Chiang et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Tumour-infiltrating T-cell subsets, molecular changes in colorectal cancer, and prognosis: cohort study and literature review

(2010) Katsuhiko Nosho et al.   JOURNAL OF PATHOLOGY

Adjuvants for cancer vaccines

(2010) Thomas W. Dubensky et al.   SEMINARS IN IMMUNOLOGY

T Cell Infiltrate Predicts Long-Term Survival Following Resection of Colorectal Cancer Liver Metastases

(2009) Steven C. Katz et al.   ANNALS OF SURGICAL ONCOLOGY