5‐Hydroxymethylcytosine as a clinical biomarker: Fluorescence‐based assay for high‐throughput epigenetic quantification in human tissues

Epigenetic Optical Mapping of 5-Hydroxymethylcytosine in Nanochannel Arrays

(2018) Tslil Gabrieli et al.   ACS Nano

In vitro diagnosis of DNA methylation biomarkers with digital PCR in breast tumors

(2018) Xingye Cui et al.   ANALYST

Loss of 5hmC identifies a new type of aberrant DNA hypermethylation in glioma

(2018) Agustin F Fernandez et al.   HUMAN MOLECULAR GENETICS

Correlated 5-Hydroxymethylcytosine (5hmC) and Gene Expression Profiles Underpin Gene and Organ-Specific Epigenetic Regulation in Adult Mouse Brain and Liver

(2017) I-Hsuan Lin et al.   PLoS One

Colorectal cancer screening

(2017) PW Chan et al.   SINGAPORE MEDICAL JOURNAL

Comprehensive analysis of normal adjacent to tumor transcriptomes

(2017) Dvir Aran et al.   Nature Communications

Single-molecule quantification of 5-hydroxymethylcytosine for diagnosis of blood and colon cancers

(2017) Noa Gilat et al.   Clinical Epigenetics

New Insights into 5hmC DNA Modification: Generation, Distribution and Function

(2017) Dong-Qiao Shi et al.   Frontiers in Genetics

Association of 5-hydroxymethylation and 5-methylation of DNA cytosine with tissue-specific gene expression

(2016) V. K. Chaithanya Ponnaluri et al.   Epigenetics

Human blood cell levels of 5-hydroxymethylcytosine (5hmC) decline with age, partly related to acquired mutations in TET2

(2016) Manuel Buscarlet et al.   EXPERIMENTAL HEMATOLOGY

Surveillance of colonic polyps: Are we getting it right?

(2016) Stewart N Bonnington   WORLD JOURNAL OF GASTROENTEROLOGY

5-Hydroxymethylcytosine localizes to enhancer elements and is associated with survival in glioblastoma patients

(2016) Kevin C. Johnson et al.   Nature Communications

Characterization of TET and IDH gene expression in chronic lymphocytic leukemia: comparison with normal B cells and prognostic significance

(2016) Michaël Van Damme et al.   Clinical Epigenetics

Forty-Year Analysis of Colonoscopic Surveillance Program for Neoplasia in Ulcerative Colitis: An Updated Overview

(2015) Chang-Ho Ryan Choi et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

One-Pot Chemoenzymatic Cascade for Labeling of the Epigenetic Marker 5-Hydroxymethylcytosine

(2015) Gil Nifker et al.   CHEMBIOCHEM

Genetics, diagnosis and management of colorectal cancer (Review)

(2015) MARINA DE ROSA et al.   ONCOLOGY REPORTS

Loss of 5-hydroxymethylcytosine and intratumoral heterogeneity as an epigenomic hallmark of glioblastoma

(2015) Theo F. J. Kraus et al.   TUMOR BIOLOGY

Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers

(2015) Michael Christoph Haffner et al.   Oncotarget

Spectroscopic Quantification of 5-Hydroxymethylcytosine in Genomic DNA

(2014) Tamar Shahal et al.   ANALYTICAL CHEMISTRY

Modulation of Ten-Eleven Translocation 1 (TET1), Isocitrate Dehydrogenase (IDH) Expression, α-Ketoglutarate (α-KG), and DNA Hydroxymethylation Levels by Interleukin-1β in Primary Human Chondrocytes

(2014) Abdul Haseeb et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

5-Hydroxymethylcytosine is a predominantly stable DNA modification

(2014) Martin Bachman et al.   Nature Chemistry

Colorectal polyps and polyposis syndromes

(2014) N. Shussman et al.   Gastroenterology Report

Optical detection of epigenetic marks: sensitive quantification and direct imaging of individual hydroxymethylcytosine bases

(2013) Yael Michaeli et al.   CHEMICAL COMMUNICATIONS

DNA methylation biomarkers and their utility for solid cancer diagnostics

(2012) Karen A. Heichman et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Recent advances in the molecular understanding of glioblastoma

(2012) Fonnet E. Bleeker et al.   JOURNAL OF NEURO-ONCOLOGY

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Decreased 5-Hydroxymethylcytosine Is Associated with Neural Progenitor Phenotype in Normal Brain and Shorter Survival in Malignant Glioma

(2012) Brent A. Orr et al.   PLoS One

Dedifferentiation of Neurons and Astrocytes by Oncogenes Can Induce Gliomas in Mice

(2012) D. Friedmann-Morvinski et al.   SCIENCE

5-Hydroxymethylcytosine Is Strongly Depleted in Human Cancers but Its Levels Do Not Correlate with IDH1 Mutations

(2011) S.-G. Jin et al.   CANCER RESEARCH

Adenoma detection rate increases with each decade of life after 50 years of age

(2011) Sarah J. Diamond et al.   GASTROINTESTINAL ENDOSCOPY

Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes

(2011) C. E. Nestor et al.   GENOME RESEARCH

Tissue Distribution of 5-Hydroxymethylcytosine and Search for Active Demethylation Intermediates

(2010) Daniel Globisch et al.   PLoS One

Efficacy of Annual Colonoscopic Surveillance in Individuals With Hereditary Nonpolyposis Colorectal Cancer

(2009) Christoph Engel et al.   Clinical Gastroenterology and Hepatology

Development of a novel mouse glioma model using lentiviral vectors

(2009) Tomotoshi Marumoto et al.   NATURE MEDICINE

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

(2009) M. Tahiliani et al.   SCIENCE

The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain

(2009) S. Kriaucionis et al.   SCIENCE

Malignant Gliomas in Adults

(2008) Patrick Y. Wen et al.   NEW ENGLAND JOURNAL OF MEDICINE