Article
Biochemistry & Molecular Biology
Patricia Gratal, Maria-Selma Arias-Perez, Lourdes Gude
Summary: In this study, a novel family of carbohydrate conjugates based on the 2-aryl-imidazo[4,5-f][1,10]phenanthroline core modified with carbohydrates (carb-APIPs) were presented. The carb-APIPs exhibited high affinity and selectivity towards telomeric G-quadruplex DNA structure, and showed significant cytotoxic properties in cancer cells.
BIOORGANIC CHEMISTRY
(2022)
Review
Chemistry, Inorganic & Nuclear
Sudhanshu Naithani, Tapas Goswami, Franck Thetiot, Sushil Kumar
Summary: This review highlights the major and recent developments in the field of luminescent anion sensing probes based on imidazo-phen scaffolds using transition metal and lanthanide complexes. The review also discusses the challenges and knowledge gaps in the field.
COORDINATION CHEMISTRY REVIEWS
(2023)
Article
Pharmacology & Pharmacy
Shujian Hu, Wantong Ma, Junyi Wang, Zhongkun Zhou, Yunhao Ma, Rentao Zhang, Kangjia Du, Hao Zhang, Mengze Sun, Xinrong Jiang, Hongyuan Tu, Xiaoliang Tang, Xiaojun Yao, Peng Chen
Summary: IPM713 has been found to inhibit colorectal cancer cells and induce apoptosis, with its anticancer effect being most significant. Additionally, IPM713 regulates the cell cycle and the PI3K/AKT/mTOR signaling pathway. Acute toxicity tests have shown it to be relatively safe.
EUROPEAN JOURNAL OF PHARMACOLOGY
(2022)
Article
Chemistry, Physical
Lucy Ellen Kapp, Marietjie Schutte-Smith, Linette Twigge, Hendrik Gideon Visser
Summary: The study reported the synthesis and crystal structures of four imidazo[4,5-f]1,10-phenanthroline type compounds, characterized by NMR spectroscopy. Some of the compounds were found to exist in two tautomeric forms. The mode of binding and intrinsic binding constant of these compounds to DNA were also investigated, showing differences in binding mechanisms among the compounds.
JOURNAL OF MOLECULAR STRUCTURE
(2022)
Article
Chemistry, Inorganic & Nuclear
Xia Zhang, Zhan Wu, Jin-Yan Xu, Wen-Xin Li, Xiu-Ling Li
Summary: The newly synthesized Cu(I) complexes exhibit good phosphorescence emissive properties in the solid state, but show significant differences in emission intensity in solution, with the neutral complexes emitting stronger phosphorescence than the ionic complexes.
Article
Materials Science, Multidisciplinary
Mei-Xin Hong, Cheng Chen, Lingyun Cao, Jun Zheng, Xiu-Ying Zheng
Summary: This study successfully synthesized two multifunctional lanthanide cluster-based luminescent materials with high quantum yield and solvent stability. Compound Eu2p exhibited ultrahigh PLQY and high stability, while compound Eu-2p showed high selectivity and sensitivity for DCN detection. These results provide new insights and strategies for the fabrication of luminescent devices based on lanthanide clusters.
JOURNAL OF MATERIALS CHEMISTRY C
(2023)
Article
Materials Science, Multidisciplinary
Yumiao Su, Wenmu Li
Summary: By synthesizing densely sulfonated poly(aryl sulfone) proton exchange membranes containing 1H-imidazo[4,5-F][1,10]-phenanthroline with metal ion coordination function, the formation of (•)OH radicals from the cleavage of H2O2 catalyzed by metal ions can be effectively prevented. The 1H-imidazo[4,5-F][1,10]-phenanthroline can induce phase separation and create a larger hydrophilic domain, which improves the antioxidant stability and possibly establishes a better connected channel for proton transport. The formation of stable interconnection points through the capture of Fe2+ and Fe3+ ions also enhances water retention and mechanical properties while preventing the generation of (OH)-O-• radicals.
ACS APPLIED POLYMER MATERIALS
(2023)
Article
Chemistry, Physical
Martin Laemmle, Benedikt Bagemihl, Djawed Nauroozi, Lydia Petermann, Andrea Pannwitz, Sven Rau
Summary: Six different monoarylated N-aryl-1H-imidazo[4,5-f][1,10]phenanthroline (Rip) ligands and their corresponding ruthenium complexes [(tbbpy)(2)Ru(Rip)](2+) Ru(Rip) have been synthesized. The structural, photophysical, photochemical, and electrochemical properties of the complexes were characterized. The results showed that the monoarylated Ru(Rip) complexes exhibited higher luminescence quantum yields compared to [Ru(bpy)(3)](2+) under inert conditions, while the Ru(RR'ip) complexes with imidazolium unit had notable loss of quantum yields.
Review
Chemistry, Inorganic & Nuclear
Sushil Kumar, Siddhant Singh, Arun Kumar, K. S. R. Murthy, Alok Kumar Singh
Summary: Ru(II)-polypyridyl complexes supported with imidazo[4,5-f][1,10]phenanthroline ligand are increasingly of interest as photosensitizers in various research areas due to their rich physicochemical characteristics and distinctive structural features. In recent years, the field has expanded significantly, with these complexes being explored for promising therapeutic and imaging applications, providing new opportunities and challenges for improved photodynamic therapy, luminescence-based sensing, and light-driven catalysis.
COORDINATION CHEMISTRY REVIEWS
(2022)
Article
Chemistry, Inorganic & Nuclear
R. Owen Bonello, Mateusz B. Pitak, Graham J. Tizzard, Simon J. Coles, Ian A. Fallis, Simon J. A. Pope
Summary: A series of new imidazo[4,5-f]-1,10-phenanthroline based ligands have been synthesized and characterized. These ligands, with conjugated aryl groups of varying functionalities, readily react with [ReBr(CO)5] to form neutral coordination complexes. The complexes exhibit fluorescent and phosphorescent properties, emitting visible light in solution.
Article
Chemistry, Inorganic & Nuclear
Rishav Das, Priyankar Paira
Summary: Selective chemotherapeutic strategies necessitate the emergence of a photosensitive scaffold to combat triple-negative breast cancer. The GSH-resistant phototoxic Ru(ii)/Ir(iii)/Re(i) based pyrene imidazophenathroline complexes showed promising activity against MDA-MB-231TNBC cells.
DALTON TRANSACTIONS
(2023)
Article
Chemistry, Multidisciplinary
Zhan Wu, Shu Cui, Zhenqin Zhao, Bingling He, Xiu-Ling Li
Summary: Previously, most of the research on phosphorescence materials focused on mononuclear and homonuclear Cu(I) complexes, while little attention has been paid to heteronuclear Cu(I) complexes. However, some heteronuclear Cu(I)-Ag(I) complexes have shown enhanced luminescence properties compared to homonuclear analogues, leading researchers to explore the synthesis and luminescence behavior of hetronuclear alpha-diimine-Cu(I)-Ag(I)-diphosphine complexes.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Applied
Andres Luengo, Isabel Marzo, Vanesa Fernandez-Moreira, M. Concepcion Gimeno
Summary: In this study, five heterobimetallic Re-I/Au-I species and one tri-metallic Re-I/Au-I/Re-I species were synthesized and fully characterized. The resultant complexes exhibited luminescence in the orange region, and the emission properties were found to be associated with the electronic properties of the gold ancillary ligand. Antiproliferative activity studies showed that only complex 4, containing a specific gold ancillary ligand, exhibited cytotoxicity in lung and cervical cancer cells.
APPLIED ORGANOMETALLIC CHEMISTRY
(2022)
Article
Pharmacology & Pharmacy
Shujian Hu, Wantong Ma, Junyi Wang, Yunhao Ma, Zhongkun Zhou, Rentao Zhang, Kangjia Du, Hao Zhang, Mengze Sun, Xinrong Jiang, Hongyuan Tu, Xiaoliang Tang, Xiaojun Yao, Peng Chen
Summary: In this study, a novel 1H-imidazole [4,5-f][1,10] phenanthroline derivative named IPM714 was synthesized and found to exhibit selective inhibitory activities against colorectal cancer cells. Functional analyses and molecular docking showed that IPM714 can suppress the PI3K/AKT/mTOR pathway to inhibit cell proliferation and regulate cell cycle and apoptosis.
EUROPEAN JOURNAL OF PHARMACOLOGY
(2022)
Article
Chemistry, Inorganic & Nuclear
Rong-Da Lai, Zeng-Kui Zhu, Yan-lan Wu, Yan-Qiong Sun, Cai Sun, Xin-Xiong Li, Shou-Tian Zheng
Summary: Two new extended polyoxometalate (POM) architectures based on lanthanide-incorporated polyoxoniobate (Ln-incorporated PONb) cages have been synthesized and structurally characterized, demonstrating a feasible strategy to develop functional POM materials. The proton conductivity and magnetic behaviors of these compounds were also studied.
INORGANIC CHEMISTRY
(2022)
Article
Chemistry, Inorganic & Nuclear
Li-Lin Luo, Xiang-Long Qu, Zheng Li, Xia Li, Hao-Ling Sun
DALTON TRANSACTIONS
(2018)
Article
Chemistry, Multidisciplinary
Jing-Ming Li, Rui Li, Xia Li
Article
Chemistry, Applied
Shanshan Li, Xin Zhou, Qiwei Xu, Dongmei Liu, Ruifang Cui, Xia Li
APPLIED ORGANOMETALLIC CHEMISTRY
(2020)
Article
Chemistry, Applied
Ruifang Cui, Rui Li, Zheng Li, Mingming Wei, Xiong Wang, Xia Li
Summary: Tb-MOF is a coordination framework with high surface area and 1D channels, capable of N-2/CO2 adsorption at low temperature. It exhibits characteristic green luminescence that is visible under 365nm near UV light, and has high sensitivity for fluorescent detection of imidacloprid and thiamethoxam in water solutions.
Article
Chemistry, Applied
Mingming Wei, Lilin Luo, Ruifang Cui, Xiong Wang, Jingyao Chen, Zelun Cai, Xia Li, Huibo Wei, Chen Wei, Zuqiang Bian
Summary: New lanthanide coordination polymers with high thermal and solvent stability were synthesized through a hydrothermal method. One of the coordination polymers showed a very high photoluminescence quantum yield and has potential applications in light conversion and antibiotic detection.
Article
Chemistry, Multidisciplinary
Xiong Wang, Qi-Wei Xu, Ming-Ming Wei, Jing-Yao Chen, Hong-Hao Wang, Xia Li
Summary: Here, we developed sensitive optical sensors for chlorogenic acid based on water-stable lanthanide coordination polymers. The synthesized Eu/Tb-CPs showed good luminescence stability and high sensitivity for chlorogenic acid, indicating their potential application value.
Article
Chemistry, Multidisciplinary
Dongmei Liu, Gaoyun Dong, Xiong Wang, Fengmei Nie, Xia Li
Article
Chemistry, Multidisciplinary
Qi-Wei Xu, Gaoyun Dong, Ruifang Cui, Xia Li
Article
Chemistry, Multidisciplinary
Qi-Wei Xu, Qiu-Shuang Wang, Shan-Shan Li, Xia Li