Article
Instruments & Instrumentation
Guangxin Liao, Zhenwei Wang, Congcong Luan, Jiapeng Liu, Xinhua Yao, Jianzhong Fu
Summary: This study demonstrates the fabrication of broadband acoustic focusing lens and asymmetric acoustic focusing lens using additive manufacturing technology, achieving focusing of acoustic waves in a wider frequency range. Experimental results show excellent performance of the designed focusing lens and asymmetric focusing lens, with good consistency between measured and simulated results.
SMART MATERIALS AND STRUCTURES
(2021)
Article
Acoustics
Liangfen Du, Abhishek Saini, Zeqing Sun, Jian Chen, Zheng Fan
Summary: Acoustic focusing has broad applications, but traditional structures have fabrication difficulties and energy transmission limitations. This study proposes a double layered acoustic grating (DLAG) to achieve high energy transmission efficiency through optimized geometry for acoustic focusing.
JOURNAL OF SOUND AND VIBRATION
(2023)
Article
Nanoscience & Nanotechnology
Zhaoyu Deng, Longsheng Zeng, Xue-Feng Zhu, Xiaozhou Liu
Summary: Ultrasonic imaging technologies have extensive applications in modern medical diagnosis and treatment. This paper utilizes a designed artificial bubble array to establish a multi-scattering sound field model, describing the nonlinear vibration and distribution of sound pressure fields. By designing the structural parameters, both fundamental and second harmonic acoustic focusing are achieved at specific locations.
Article
Computer Science, Information Systems
Weiguo Wang, Jinming Li, Yuan He, Yunhao Liu
Summary: This work introduces Symphony, the first complete solution for concurrently localizing multiple acoustic sources with a single smart device. The method takes advantage of the geometric layout of microphones to determine the unique relationship among signals from the same source. Theoretical models and evaluations show that Symphony achieves a median localization error of 0.662 m.
IEEE TRANSACTIONS ON MOBILE COMPUTING
(2023)
Article
Acoustics
Tianquan Tang, Lixi Huang
Summary: This study examines the acoustic forces exerted on large particles by time-harmonic waves, taking into account the scattering effects of multiple sources and particles. The results show that the contribution of scattering waves becomes significant when the size parameter is greater than 2, and increases quadratically with the amplitude parameter of the transducers. The theoretical predictions are validated through finite element simulations and applied to more complex scenarios involving multiple particles manipulated by multiple transducers.
JOURNAL OF SOUND AND VIBRATION
(2021)
Article
Crystallography
Qinglei Zeng, Shenlian Gao, Yun Lai, Xiaozhou Liu
Summary: In this paper, we demonstrate the remarkable improvement in the directionality of acoustic radiation at low frequencies by using acoustic metamaterials arranged as an array of quadrupoles, compared with previous metamaterials arranged as monopole and dipole structures. The directivity can be adjusted by changing the characteristic parameter and symmetry of the structure, providing a flexible method of adjusting radiation directions. Furthermore, the directionality can be further improved by constructing a linear array. This work establishes the control of acoustic radiation via quadrupolar metamaterials.
Article
Acoustics
Songling Huang, Lisha Peng, Hongyu Sun, Qing Wang, Wei Zhao, Shen Wang
Summary: This study investigated the focusing performance of a specific acoustic lens at different working frequencies, analyzing the band structure, wave intensity distribution, reflection and transmission coefficients, and refractive index of a unit cell through simulation and experiment. The research showed that the sound field intensity at the focal point of the acoustic lens increased with frequency, providing a method for designing acoustic lenses with different working frequencies.
Article
Multidisciplinary Sciences
B. L. N. Kennett
Summary: Distributed acoustic sensing (DAS) using fibre optic cables allows for high-density sampling of seismic wavefields. The nature of the signal depends on the positioning of the cable with respect to the passing seismic waves. The slowness-domain representation of the DAS signal provides insight into the wavefield characteristics in different scenarios.
PROCEEDINGS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES
(2022)
Article
Engineering, Multidisciplinary
Yuanwen Li, Min Li, Wei Pan, Daofang Feng, Debin Yang
Summary: This paper introduces an iterative time reversal (iterative-TR) processing method for sub-wavelength focusing and improvement of spatial resolution at low frequencies. Numerical simulations and experimental results show that this method can effectively break the diffraction limit and stably determine the positions of multiple sound sources, with good performance.
MEASUREMENT SCIENCE AND TECHNOLOGY
(2022)
Article
Physics, Applied
Yuanyan Zhao, Sriram Subramanian, Gianluca Memoli
Summary: The paper introduces a solution based on sonic crystals, called a 2.5D lens, which can focus the emission of a standard loudspeaker in 3D space. The authors use finite-element simulations to describe the underlying theory and manufacture two lenses for experimental validation, showing that the efficiency of the lenses strongly depends on how the sound is delivered.
APPLIED PHYSICS LETTERS
(2021)
Article
Materials Science, Multidisciplinary
Michael Sammon, Dionisios Margetis, E. J. Mele, Tony Low
Summary: Nonreciprocal plasmons in current-driven, isotropic, and homogenous graphene with proximal metallic gates are theoretically explored, showing linearly dispersive acoustic plasmons close to its particle-hole continuum counterpart. The applied bias leads to spectral broadband focused plasmons with resonance linewidth dependent on the angular direction relative to the current flow, and forward focused nonreciprocal plasmons are predicted with accessible experimental parameters and setup.
Article
Nanoscience & Nanotechnology
Yongkui Tang, Eun Sok Kim
Summary: This paper introduces new and improved types of acoustic lenses (ACFALs) based on different materials, manufactured through a simple sacrificial-layer-free microfabrication process. The effect of lens thickness on acoustic transmittance is studied and thickness control techniques are optimized. These techniques are useful for manufacturing high-performance ACFALs and other miniaturized devices.
MICROSYSTEMS & NANOENGINEERING
(2022)
Article
Engineering, Civil
Valentin Baron, Arthur Finez, Simon Bouley, Florent Fayet, Jerome I. Mars, Barbara Nicolas
Summary: As deep-sea mining of natural deposits becomes more cost competitive, companies are turning to seabed mining, which can have a significant acoustic impact on the surrounding environment. In order to predict and understand this noise, a 3-D prototype acoustic array has been designed and deployed at sea to localize and quantify the noise sources. The array design method involved selecting the shape and hydrophone arrangement based on metrics such as maximum sidelobe levels and spatial resolution, resulting in a tip down conical array with 21 hydrophones that was successfully validated in a real-life setting in the Mediterranean Sea.
IEEE JOURNAL OF OCEANIC ENGINEERING
(2021)
Article
Mechanics
Sen Xue, Xiwen Zhang, Feng He, Zhaomiao Liu, Pengfei Hao
Summary: The study investigates the effects of the tilted angle of the acoustic field and microchannel aspect ratios on particle manipulation, proposing an optimal tilt angle for efficient separation of particles. It also identifies two typical particle migration states and observes multi-layer particle focus in the vertical direction of microchannels for the first time, providing new insights for the development of high-throughput microfluidic devices.
Article
Acoustics
Qi Li, Jiapu Li, Haobo Zhu, Yujie Chen, Benpeng Zhu, Hongbin Yu
Summary: This paper proposes a new strategy for constructing a focus-tunable photoacoustic transmitter, which innovatively designs a sandwich-like photoacoustic conversion layer for continuous tuning. Successful demonstration of continuous tuning on the axial focusing length of the acoustic field has been achieved in the photoacoustic transmitter for the first time.
Article
Medicine, Research & Experimental
Jian-Ping Xia, Sheng-Qiang Liu, Shuai Wang
Summary: Conbercept significantly inhibited retinal pathological changes, inflammation, and oxidative response in PDR mice, revealing its molecular mechanisms in treating PDR.
Article
Multidisciplinary Sciences
Haodong Zhu, Peiran Zhang, Zhanwei Zhong, Jianping Xia, Joseph Rich, John Mai, Xingyu Su, Zhenhua Tian, Hunter Bachman, Joseph Rufo, Yuyang Gu, Putong Kang, Krishnendu Chakrabarty, Thomas P. Witelski, Tony Jun Huang
Summary: Acoustohydrodynamic tweezers present a novel method for contact-free manipulation of bioanalytes by generating stable vortex pairs to create hydrodynamic traps for object manipulation. This technology allows for predictable control of flow fields and precise handling of droplets or particles, showcasing improved control over acoustic streaming and digitalized liquid handling.
Article
Multidisciplinary Sciences
Peiran Zhang, Joseph Rufo, Chuyi Chen, Jianping Xia, Zhenhua Tian, Liying Zhang, Nanjing Hao, Zhanwei Zhong, Yuyang Gu, Krishnendu Chakrabarty, Tony Jun Huang
Summary: This study introduces acoustoelectronic nanotweezers, which combine the precision of electronic tweezers with the large-field dynamic control of acoustic tweezers, demonstrating complex patterning of sub-100nm objects.
NATURE COMMUNICATIONS
(2021)
Article
Biophysics
Nanjing Hao, Zeyu Wang, Pengzhan Liu, Ryan Becker, Shujie Yang, Kaichun Yang, Zhichao Pei, Peiran Zhang, Jianping Xia, Liang Shen, Lin Wang, Kathleen A. Welsh-Bohmer, Laurie Sanders, Luke P. Lee, Tony Jun Huang
Summary: Alzheimer's disease is a severe neurodegenerative disorder with early diagnosis being a challenge. Researchers have developed an integrated diagnostic system combining acoustics, microfluidics, and biosensors for accurate and rapid detection of AD biomarkers, showing promising results for early diagnosis.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Optics
Zijie Zhao, Jianping Xia, Tony Jun Huang, Jun Zou
Summary: This Letter presents a ring-shaped photoacoustic tweezers capable of manipulating micron-sized particles. By illuminating an absorptive liquid medium with a pulsed laser beam, acoustic radiation force and vaporization repulsion are generated, enabling continuous and versatile movement of single or multiple particles. The tweezers demonstrate interactions between particles, including separation, attachment, and grouping, combining the advantages of optical and acoustic tweezers.
Editorial Material
Plant Sciences
Duan-chong Liu, Wen-xia Zhao, Jian-ping Xia, San-shan Cai, Wen-xia Huai, Ru-bin Zhang, Bin Li
Article
Chemistry, Physical
Shujie Yang, Zhenhua Tian, Zeyu Wang, Joseph Rufo, Peng Li, John Mai, Jianping Xia, Hunter Bachman, Po-Hsun Huang, Mengxi Wu, Chuyi Chen, Luke P. Lee, Tony Jun Huang
Summary: The authors introduce a harmonic acoustics platform for non-contact and dynamic particle manipulation. This method enables precise assembly of colloidal crystals or cells and measurement of intercellular adhesion forces, with subwavelength resolution and high throughput.
Article
Nanoscience & Nanotechnology
Geonsoo Jin, Joseph Rich, Jianping Xia, Albert J. He, Chenglong Zhao, Tony Jun Huang
Summary: Combining nanoscale optical resolution with a large field of view is crucial in many research and industry areas. To overcome limitations of existing scanning microscopes, a dual-camera acoustofluidic nanoscope has been developed, allowing for precise imaging of samples and microspheres simultaneously. This innovation reduces the number of images needed for capturing the entire field of view by 55-fold compared to previous designs, while greatly improving image quality through an alpha-blending imaging technique.
MICROSYSTEMS & NANOENGINEERING
(2022)
Article
Physics, Multidisciplinary
Jianping Xia, Ye-Yang Sun, Yi-Jun Guan, Yin Wang, Yu-Jing Lu, Hui-Gang Hu, Yong Ge, Hong-Xiang Sun, Shou-Qi Yuan, Yun Lai, Xiao-Jun Liu
Summary: We report that near-perfect absorption of low-frequency sound can be achieved in an open tunnel embedded with two deep sub-wavelength Mie resonators. The resonators, consisting of a multiple-cavity structure and an outer frame, exhibit high performances of coupling and sound absorption. By increasing the number of resonators in the tunnel, a broadband near-perfect sound absorption is observed.
FRONTIERS IN PHYSICS
(2022)
Article
Multidisciplinary Sciences
Jinxin Zhang, Chuyi Chen, Ryan Becker, Joseph Rufo, Shujie Yang, John Mai, Peiran Zhang, Yuyang Gu, Zeyu Wang, Zhehan Ma, Jianping Xia, Nanjing Hao, Zhenhua Tian, David T. W. Wong, Yoel Sadovsky, Luke P. Lee, Tony Jun Huang
Summary: This study presents a technique called ANSWER, which allows for rapid and high-purity fractionation of sEV subpopulations from biofluids. The technique utilizes excitation resonance to generate pillar-like acoustic fields, enabling precise separation of particles in a size-selective manner without the need for sample preprocessing or complex nanofabrication methods.
Article
Computer Science, Hardware & Architecture
Zhiting Lin, Shaoying Zhang, Qian Jin, Jianping Xia, Yunwei Liu, Kefeng Yu, Jian Zheng, Xiaoming Xu, Xing Fan, Ke Li, Zhongzhen Tong, Xiulong Wu, Wenjuan Lu, Chunyu Peng, Qiang Zhao
Summary: This study proposes a fully digital SRAM-based IMC architecture that simplifies multiplication, improves computational efficiency, and is easily scalable.
IEEE TRANSACTIONS ON VERY LARGE SCALE INTEGRATION (VLSI) SYSTEMS
(2023)
Article
Physics, Applied
Yong Ge, Bin-jie Shi, Jian-ping Xia, Hong-xiang Sun, Shou-qi Yuan, Haoran Xue, Baile Zhang
Summary: This article introduces a one-dimensional acoustic topological insulator (ATI) where the zero-dimensional topological interface states can deliver information from one location to another through a movable interface. By programming coding sequences of switchable elements 1 and 0, movable zero-dimensional topological interface states are realized. This work opens up avenues for developing topological acoustic devices with programmable and dynamic functions.
APPLIED PHYSICS REVIEWS
(2023)
Review
Public, Environmental & Occupational Health
Pingping Cao, Xufang Ye, Jianping Xia
Summary: Malaria is a major global health problem, with the goals of the global malaria elimination program aiming to significantly reduce malaria cases and deaths, eliminate malaria in certain countries, and prevent resurgence of the disease. Currently, the main strategy for malaria elimination relies on chemotherapy using various antimalarials. Traditional Chinese medicines, such as artemisinin extracted from Artemisia annua, have shown effectiveness in treating malaria. Other traditional Chinese medicines, including ginger, garlic, and certain plant species, have also demonstrated antiplasmodial activities and potential for malaria treatment. Further clinical trials are needed to evaluate the efficacy and safety of these medicines and understand their underlying mechanisms.
SOUTHEAST ASIAN JOURNAL OF TROPICAL MEDICINE AND PUBLIC HEALTH
(2023)
Article
Multidisciplinary Sciences
Bogdan Mateescu, Jennifer C. Jones, Roger P. Alexander, Eric Alsop, Ji Yeong An, Mohammad Asghari, Alex Boomgarden, Laura Bouchareychas, Alfonso Cayota, Hsueh-Chia Chang, Al Charest, Daniel T. Chiu, Robert J. Coffey, Saumya Das, Peter De Hoff, Andrew de Mello, Crislyn D'Souza-Schorey, David Elashoff, Kiarash R. Eliato, Jeffrey L. Franklin, David J. Galas, Mark B. Gerstein, Ionita H. Ghiran, David B. Go, Stephen Gould, Tristan R. Grogan, James N. Higginbotham, Florian Hladik, Tony Jun Huang, Xiaoye Huo, Elizabeth Hutchins, Dennis K. Jeppesen, Tijana Jovanovic-Talisman, Betty Y. S. Kim, Sung Kim, Kyoung-Mee Kim, Yong Kim, Robert R. Kitchen, Vaughan Knouse, Emily L. LaPlante, Carlito B. Lebrilla, L. James Lee, Kathleen M. Lennon, Guoping Li, Feng Li, Tieyi Li, Tao Liu, Zirui Liu, Adam L. Maddox, Kyle McCarthy, Bessie Meechoovet, Nalin Maniya, Yingchao Meng, Aleksandar Milosavljevic, Byoung-Hoon Min, Amber Morey, Martin Ng, John Nolan, Getulio P. De Oliveira Junior, Michael E. Paulaitis, Tuan Anh Phu, Robert L. Raffai, Matthew E. Roth, David A. Routenberg, Joel Rozowsky, Joseph Rufo, Satyajyoti Senapati, Sigal Shachar, Himani Sharma, Anil K. Sood, Stavros Stavrakis, Alessandra Sturchler, Muneesh Tewari, Juan P. Tosar, Alexander K. Tucker-Schwartz, Andrey Turchinovich, Nedyalka Valkov, Kendall Van Keuren-Jensen, Kasey C. Vickers, Lucia Vojtech, Wyatt N. Vreeland, Ceming Wang, Kai Wang, ZeYu Wang, Joshua A. Welsh, Kenneth W. Witwer, David T. W. Wong, Jianping Xia, Ya-Hong Xie, Kaichun Yang, Mikolaj P. Zaborowski, Chenguang Zhang, Qin Zhang, Angela M. Zivkovic, Louise C. Laurent
Summary: The extracellular RNA communication consortium (ERCC) is a NIH-funded program that aims to advance the development of new technologies, resources, and knowledge about exRNAs and their carriers. Through its second phase (ERCC2), the program focuses on addressing important gaps in knowledge and technology, as well as promoting collaboration between ERCC2 members and the scientific community. The ultimate goal is to enhance our understanding of exRNA biology and improve the development of accurate and efficient exRNA-based diagnostic methods.
Article
Biochemical Research Methods
Geonsoo Jin, Seongwoo Hong, Joseph Rich, Jianping Xia, Kyeri Kim, Lingchong You, Chenglong Zhao, Tony Jun Huang
Summary: Machine learning image recognition and classification in the field of nanotechnology face challenges in image resolution, field of view, and processing time. To overcome these challenges, researchers have developed an intelligent nanoscope that combines machine learning and microsphere array-based imaging, allowing for high-resolution images with a large field of view, as well as rapid classification of nanomaterials using a deep convolution neural network.
