p62/SQSTM1 protects against cisplatin-induced oxidative stress in kidneys by mediating the cross talk between autophagy and the Keap1-Nrf2 signalling pathway

Trehalose protects against oxidative stress by regulating the Keap1–Nrf2 and autophagy pathways

(2018) Yuhei Mizunoe et al.   Redox Biology

MicroRNA-140-5p attenuated oxidative stress in Cisplatin induced acute kidney injury by activating Nrf2/ARE pathway through a Keap1-independent mechanism

(2017) Weitang Liao et al.   EXPERIMENTAL CELL RESEARCH

Augmented O-GlcNAc signaling via glucosamine attenuates oxidative stress and apoptosis following contrast-induced acute kidney injury in rats

(2017) Jiachang Hu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Autophagy as a regulator of cardiovascular redox homeostasis

(2017) Ye Yan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Autophagy is involved in mouse kidney development and podocyte differentiation regulated by Notch signalling

(2017) Chuyue Zhang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Arsenic Induces p62 Expression to Form a Positive Feedback Loop with Nrf2 in Human Epidermal Keratinocytes: Implications for Preventing Arsenic-Induced Skin Cancer

(2017) Palak Shah et al.   MOLECULES

Oxidative Stress and Acute Kidney Injury in Critical Illness: Pathophysiologic Mechanisms—Biomarkers—Interventions, and Future Perspectives

(2017) Paraskevi Pavlakou et al.   Oxidative Medicine and Cellular Longevity

Knockout of Eva1a leads to rapid development of heart failure by impairing autophagy

(2017) Shu Zhang et al.   Cell Death & Disease

Continued 26S proteasome dysfunction in mouse brain cortical neurons impairs autophagy and the Keap1-Nrf2 oxidative defence pathway

(2017) Aslihan Ugun-Klusek et al.   Cell Death & Disease

Autophagy deficient keratinocytes display increased DNA damage, senescence and aberrant lipid composition after oxidative stress in vitro and in vivo

(2017) Xiuzu Song et al.   Redox Biology

Eupatilin induces Sestrin2-dependent autophagy to prevent oxidative stress

(2016) Kyung Hwan Jegal et al.   APOPTOSIS

SQSTM1/p62 mediates crosstalk between autophagy and the UPS in DNA repair

(2016) Graeme Hewitt et al.   Autophagy

HSF1 stress response pathway regulates autophagy receptor SQSTM1/p62-associated proteostasis

(2016) Yoshihisa Watanabe et al.   Autophagy

Excessive apoptosis and defective autophagy contribute to developmental testicular toxicity induced by fluoride

(2016) Shun Zhang et al.   ENVIRONMENTAL POLLUTION

Autophagy in acute kidney injury

(2016) Gur P. Kaushal et al.   KIDNEY INTERNATIONAL

Carbon disulfide activates p62-Nrf2-keap1 pathway in rat nerve tissues

(2016) Shasha Wang et al.   TOXICOLOGY

p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming

(2016) Tetsuya Saito et al.   Nature Communications

The autophagy pathway maintained signaling crosstalk with the Keap1–Nrf2 system through p62 in auditory cells under oxidative stress

(2015) Ken Hayashi et al.   CELLULAR SIGNALLING

Acute kidney injury according to KDIGO stages and maternal mortality in the intensive care unit

(2015) Y. Bentata et al.   INTENSIVE CARE MEDICINE

p62/SQSTM1 at the interface of aging, autophagy, and disease

(2014) Alessandro Bitto et al.   AGE

The NRF2-KEAP1 Pathway Is an Early Responsive Gene Network in Arsenic Exposed Lymphoblastoid Cells

(2014) Emilio J. Córdova et al.   PLoS One

The Role of the Selective Adaptor p62 and Ubiquitin-Like Proteins in Autophagy

(2014) Mónika Lippai et al.   Biomed Research International

Autophagy in Kidney Health and Disease

(2013) Zhibo Wang et al.   ANTIOXIDANTS & REDOX SIGNALING

Astragaloside IV prevents acute kidney injury in two rodent models by inhibiting oxidative stress and apoptosis pathways

(2013) Dingkun Gui et al.   APOPTOSIS

Autolysosomal β-catenin degradation regulates Wnt-autophagy-p62 crosstalk

(2013) Katy J Petherick et al.   EMBO JOURNAL

Role of Nrf2 in protection against acute kidney injury

(2013) Luke M. Shelton et al.   KIDNEY INTERNATIONAL

Inhibition of autophagy promotes CYP2E1-dependent toxicity in HepG2 cells via elevated oxidative stress, mitochondria dysfunction and activation of p38 and JNK MAPK

(2013) Defeng Wu et al.   Redox Biology

Autophagy Guards Against Cisplatin-Induced Acute Kidney Injury

(2012) Atsushi Takahashi et al.   AMERICAN JOURNAL OF PATHOLOGY

Emerging role of autophagy in kidney function, diseases and aging

(2012) Tobias B. Huber et al.   Autophagy

Autophagy protects proximal tubular cells from injury and apoptosis

(2012) Gur P. Kaushal   KIDNEY INTERNATIONAL

Acute kidney injury

(2012) Rinaldo Bellomo et al.   LANCET

p62 at the Interface of Autophagy, Oxidative Stress Signaling, and Cancer

(2011) Ioannis P. Nezis et al.   ANTIOXIDANTS & REDOX SIGNALING

The protective role of autophagy against aging and acute ischemic injury in kidney proximal tubular cells

(2011) Yoshitaka Isaka et al.   Autophagy

Autophagy and p62 in Cardiac Proteinopathy

(2011) Qingwen Zheng et al.   CIRCULATION RESEARCH

Autophagy Protects the Proximal Tubule from Degeneration and Acute Ischemic Injury

(2011) T. Kimura et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Autophagy Is a Renoprotective Mechanism During in Vitro Hypoxia and in Vivo Ischemia-Reperfusion Injury

(2010) Man Jiang et al.   AMERICAN JOURNAL OF PATHOLOGY

p62/SQSTM1Is a Target Gene for Transcription Factor NRF2 and Creates a Positive Feedback Loop by Inducing Antioxidant Response Element-driven Gene Transcription

(2010) Ashish Jain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Noncanonical Mechanism of Nrf2 Activation by Autophagy Deficiency: Direct Interaction between Keap1 and p62

(2010) A. Lau et al.   MOLECULAR AND CELLULAR BIOLOGY

Transcription factor Nrf2 is protective during ischemic and nephrotoxic acute kidney injury in mice

(2009) Manchang Liu et al.   KIDNEY INTERNATIONAL

Autophagy is cytoprotective during cisplatin injury of renal proximal tubular cells

(2008) Sudharsan Periyasamy-Thandavan et al.   KIDNEY INTERNATIONAL