Design of α-helical antimicrobial peptides with a high selectivity index
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Design of α-helical antimicrobial peptides with a high selectivity index
Authors
Keywords
-
Journal
Expert Opinion on Drug Discovery
Volume -, Issue -, Pages 1-11
Publisher
Informa UK Limited
Online
2019-07-17
DOI
10.1080/17460441.2019.1642322
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Helical antimicrobial peptides assemble into protofibril scaffolds that present ordered dsDNA to TLR9
- (2019) Ernest Y. Lee et al. Nature Communications
- Potent and Broad-Spectrum Antimicrobial Activity of Analogs from the Scorpion Peptide Stigmurin
- (2019) Bruno Amorim-Carmo et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Selection and redesign for high selectivity of membrane-active antimicrobial peptides from a dedicated sequence/function database
- (2019) Tomislav Rončević et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Molecular Dynamics Simulations Are Redefining Our View of Peptides Interacting with Biological Membranes
- (2018) Jakob P. Ulmschneider et al. ACCOUNTS OF CHEMICAL RESEARCH
- Central β-turn increases the cell selectivity of imperfectly amphipathic α-helical peptides
- (2018) Changxuan Shao et al. Acta Biomaterialia
- Synergism of Antimicrobial Frog Peptides Couples to Membrane Intrinsic Curvature Strain
- (2018) Regina Leber et al. BIOPHYSICAL JOURNAL
- Antibacterial Activity Affected by the Conformational Flexibility in Glycine–Lysine Based α-Helical Antimicrobial Peptides
- (2018) Tomislav Rončević et al. JOURNAL OF MEDICINAL CHEMISTRY
- Large scale ab initio modeling of structurally uncharacterized antimicrobial peptides reveals known and novel folds
- (2018) Mara Kozic et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- Antimicrobial Peptides: Interaction With Model and Biological Membranes and Synergism With Chemical Antibiotics
- (2018) Axel Hollmann et al. Frontiers in Chemistry
- Cell-selectivity of tryptophan and tyrosine in amphiphilic α-helical antimicrobial peptides against drug-resistant bacteria
- (2018) Min-Young Lee et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- OUP accepted manuscript
- (2018) JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Structure-activity relationship study of the antimicrobial CRAMP-derived peptide CRAMP20-33
- (2018) Sofie Winderickx et al. PEPTIDES
- An engineered arginine-rich α-helical antimicrobial peptide exhibits broad-spectrum bactericidal activity against pathogenic bacteria and reduces bacterial infections in mice
- (2018) Chin-Hao Yang et al. Scientific Reports
- A novel cecropin B-derived peptide with antibacterial and potential anti-inflammatory properties
- (2018) Jiarong Wang et al. PeerJ
- Designed peptide with a flexible central motif from ranatuerins adapts its conformation to bacterial membranes
- (2018) Davor Juretić et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Glycine-replaced derivatives of [Pro 3 ,DLeu 9 ]TL, a temporin L analogue: Evaluation of antimicrobial, cytotoxic and hemolytic activities
- (2017) Francesco Merlino et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- LL-37-derived short antimicrobial peptide KR-12-a5 and its d -amino acid substituted analogs with cell selectivity, anti-biofilm activity, synergistic effect with conventional antibiotics, and anti-inflammatory activity
- (2017) Eun Young Kim et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Lipid topology and electrostatic interactions underpin lytic activity of linear cationic antimicrobial peptides in membranes
- (2017) David J. Paterson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The cytotoxic Staphylococcus aureus PSMα3 reveals a cross-α amyloid-like fibril
- (2017) Einav Tayeb-Fligelman et al. SCIENCE
- Molecular mechanism of synergy between the antimicrobial peptides PGLa and magainin 2
- (2017) Jonathan Zerweck et al. Scientific Reports
- Single Amino Acid Substitutions at Specific Positions of the Heptad Repeat Sequence of Piscidin-1 Yielded Novel Analogs That Show Low Cytotoxicity andIn VitroandIn VivoAntiendotoxin Activity
- (2016) Amit Kumar et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Improving short antimicrobial peptides despite elusive rules for activity
- (2016) Ralf Mikut et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Alanine scan and 2 H NMR analysis of the membrane-active peptide BP100 point to a distinct carpet mechanism of action
- (2016) Héctor Zamora-Carreras et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Lipopolysaccharide-bound structure of the antimicrobial peptide cecropin P1 determined by nuclear magnetic resonance spectroscopy
- (2016) Mi-Hwa Baek et al. JOURNAL OF PEPTIDE SCIENCE
- Computational resources and tools for antimicrobial peptides
- (2016) Shicai Liu et al. JOURNAL OF PEPTIDE SCIENCE
- Antimicrobial Activity and Stability of Short and Long Based Arachnid Synthetic Peptides in the Presence of Commercial Antibiotics
- (2016) Ivan Arenas et al. MOLECULES
- Mapping membrane activity in undiscovered peptide sequence space using machine learning
- (2016) Ernest Y. Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Triple-targeting Gram-negative selective antimicrobial peptides capable of disrupting the cell membrane and lipid A biosynthesis
- (2016) T. M. Postma et al. RSC Advances
- A Web Server and Mobile App for Computing Hemolytic Potency of Peptides
- (2016) Kumardeep Chaudhary et al. Scientific Reports
- Antimicrobial activity, improved cell selectivity and mode of action of short PMAP-36-derived peptides against bacteria and Candida
- (2016) Yinfeng Lyu et al. Scientific Reports
- High Selective Performance of Designed Antibacterial and Anticancer Peptide Amphiphiles
- (2015) Cuixia Chen et al. ACS Applied Materials & Interfaces
- Rational design of mirror-like peptides with alanine regulation
- (2015) Weizhong Li et al. AMINO ACIDS
- A novel fragment based strategy for membrane active antimicrobials against MRSA
- (2015) Jianguo Li et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Antimicrobial activity of synthetic cationic peptides and lipopeptides derived from human lactoferricin against Pseudomonas aeruginosa planktonic cultures and biofilms
- (2015) Susana Sánchez-Gómez et al. BMC MICROBIOLOGY
- Role of peptide self-assembly in antimicrobial peptides
- (2015) Xibo Tian et al. JOURNAL OF PEPTIDE SCIENCE
- Quasiracemate Crystal Structures of Magainin 2 Derivatives Support the Functional Significance of the Phenylalanine Zipper Motif
- (2015) Zvi Hayouka et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- CAMPR3: a database on sequences, structures and signatures of antimicrobial peptides: Table 1.
- (2015) Faiza Hanif Waghu et al. NUCLEIC ACIDS RESEARCH
- DBAASP v.2: an enhanced database of structure and antimicrobial/cytotoxic activity of natural and synthetic peptides
- (2015) Malak Pirtskhalava et al. NUCLEIC ACIDS RESEARCH
- APD3: the antimicrobial peptide database as a tool for research and education
- (2015) Guangshun Wang et al. NUCLEIC ACIDS RESEARCH
- Precision-guided antimicrobial peptide as a targeted modulator of human microbial ecology
- (2015) Lihong Guo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Formation of functional super-helical assemblies by constrained single heptad repeat
- (2015) Sudipta Mondal et al. Nature Communications
- Hydrophobic mismatch demonstrated for membranolytic peptides and their use as molecular rulers to measure bilayer thickness in native cells
- (2015) Ariadna Grau-Campistany et al. Scientific Reports
- Comparative Evaluation of the Antimicrobial Activity of Different Antimicrobial Peptides against a Range of Pathogenic Bacteria
- (2015) Anna Ebbensgaard et al. PLoS One
- Functional Roles of Aromatic Residues and Helices of Papiliocin in its Antimicrobial and Anti-inflammatory Activities
- (2015) Eunjung Lee et al. Scientific Reports
- Trichoplaxin — A new membrane-active antimicrobial peptide from placozoan cDNA
- (2014) Juraj Simunić et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Rational Design of Alpha-Helical Antimicrobial Peptides: Do's and Don'ts
- (2014) Lars Erik Uggerhøj et al. CHEMBIOCHEM
- Structure-activity study of macropin, a novel antimicrobial peptide from the venom of solitary beeMacropis fulvipes(Hymenoptera: Melittidae)
- (2014) Lenka Monincová et al. JOURNAL OF PEPTIDE SCIENCE
- Conformational analysis and cytotoxic activities of the frog skin host-defense peptide, hymenochirin-1Pa
- (2014) Ilaria Serra et al. PEPTIDES
- Low Structural Variation in the Host-Defense Peptide Repertoire of the Dwarf Clawed Frog Hymenochirus boettgeri (Pipidae)
- (2014) Severine Matthijs et al. PLoS One
- Role of Phenylalanine and Valine10 Residues in the Antimicrobial Activity and Cytotoxicity of Piscidin-1
- (2014) Eunjung Lee et al. PLoS One
- Real-time Measurement of Membrane Conformational States Induced by Antimicrobial Peptides: Balance Between Recovery and Lysis
- (2014) Kristopher Hall et al. Scientific Reports
- Design of imperfectly amphipathic α-helical antimicrobial peptides with enhanced cell selectivity
- (2013) Xin Zhu et al. Acta Biomaterialia
- Flexibility is a mechanical determinant of antimicrobial activity for amphipathic cationic α-helical antimicrobial peptides
- (2013) Li Liu et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Design of short membrane selective antimicrobial peptides containing tryptophan and arginine residues for improved activity, salt-resistance, and biocompatibility
- (2013) Rathi Saravanan et al. BIOTECHNOLOGY AND BIOENGINEERING
- Biomolecular engineering of a human beta defensin model for increased salt resistance
- (2013) Xiang Li et al. CHEMICAL ENGINEERING SCIENCE
- The importance of being kinked: role of Pro residues in the selectivity of the helical antimicrobial peptide P5
- (2013) Sara Bobone et al. JOURNAL OF PEPTIDE SCIENCE
- Hemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides
- (2013) Ankur Gautam et al. NUCLEIC ACIDS RESEARCH
- Activity Determinants of Helical Antimicrobial Peptides: A Large-Scale Computational Study
- (2013) Yi He et al. PLoS One
- Design and characterization of novel antimicrobial peptides, R-BP100 and RW-BP100, with activity against Gram-negative and Gram-positive bacteria
- (2012) Inês M. Torcato et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Selective antimicrobial activity and mode of action of adepantins, glycine-rich peptide antibiotics based on anuran antimicrobial peptide sequences
- (2012) Nada Ilić et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- A novel antimicrobial peptide derived from modified N-terminal domain of bovine lactoferrin: Design, synthesis, activity against multidrug-resistant bacteria and Candida
- (2012) Biswajit Mishra et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Antimicrobial peptides containing unnatural amino acid exhibit potent bactericidal activity against ESKAPE pathogens
- (2012) R.P. Hicks et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Improving the Selectivity of Antimicrobial Peptides from Anuran Skin
- (2012) Nédia Kamech et al. Journal of Chemical Information and Modeling
- Conformational and membrane interaction studies of the antimicrobial peptide alyteserin-1c and its analogue [E4K]alyteserin-1c
- (2011) Anusha P. Subasinghage et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Knowledge-based computational methods for identifying or designing novel, non-homologous antimicrobial peptides
- (2011) Davor Juretić et al. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
- Identification of antimicrobial peptides from teleosts and anurans in expressed sequence tag databases using conserved signal sequences
- (2011) Valentina Tessera et al. FEBS Journal
- Antimicrobial Properties of Amyloid Peptides
- (2011) Bruce L. Kagan et al. MOLECULAR PHARMACEUTICS
- Probing the “Charge Cluster Mechanism” in Amphipathic Helical Cationic Antimicrobial Peptides
- (2010) Raquel F. Epand et al. BIOCHEMISTRY
- Antimicrobial peptides bind more strongly to membrane pores
- (2010) Maja Mihajlovic et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Rational Design of Tryptophan-Rich Antimicrobial Peptides with Enhanced Antimicrobial Activities and Specificities
- (2010) Hui-Yuan Yu et al. CHEMBIOCHEM
- Designed low amphipathic peptides with α-helical propensity exhibiting antimicrobial activity via a lipid domain formation mechanism
- (2010) Naoki Yamamoto et al. PEPTIDES
- Design of Nontoxic Analogues of Cathelicidin-Derived Bovine Antimicrobial Peptide BMAP-27: The Role of Leucine as Well as Phenylalanine Zipper Sequences in Determining Its Toxicity
- (2009) Aqeel Ahmad et al. BIOCHEMISTRY
- Computational Design of Highly Selective Antimicrobial Peptides
- (2009) Davor Juretić et al. Journal of Chemical Information and Modeling
- Use of Artificial Intelligence in the Design of Small Peptide Antibiotics Effective against a Broad Spectrum of Highly Antibiotic-Resistant Superbugs
- (2008) Artem Cherkasov et al. ACS Chemical Biology
- Solid-State NMR Analysis Comparing the Designer-Made Antibiotic MSI-103 with Its Parent Peptide PGLa in Lipid Bilayers†
- (2008) Erik Strandberg et al. BIOCHEMISTRY
- Mechanism of Antibacterial Action of Dermaseptin B2: Interplay between Helix−Hinge−Helix Structure and Membrane Curvature Strain†
- (2008) Cécile Galanth et al. BIOCHEMISTRY
- Structure, membrane orientation, mechanism, and function of pexiganan — A highly potent antimicrobial peptide designed from magainin
- (2008) Lindsey M. Gottler et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Control of cell selectivity of antimicrobial peptides
- (2008) Katsumi Matsuzaki BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Conformational analysis of the broad-spectrum antibacterial peptide, ranatuerin-2CSa: Identification of a full length helix–turn–helix motif
- (2008) Anusha P. Subasinghage et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- HELIQUEST: a web server to screen sequences with specific -helical properties
- (2008) R. Gautier et al. BIOINFORMATICS
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started