Effects of novel somatostatin-dopamine chimeric drugs in 2D and 3D cell culture models of neuroendocrine tumors

Octreotide Does Not Inhibit Proliferation in Five Neuroendocrine Tumor Cell Lines

(2018) Samantha Exner et al.   Frontiers in Endocrinology

Pituitary Tumor Suppression by Combination of Cabergoline and Chloroquine

(2017) Shao Jian Lin et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The components of somatostatin and ghrelin systems are altered in neuroendocrine lung carcinoids and associated to clinical-histological features

(2017) Aura D. Herrera-Martínez et al.   LUNG CANCER

ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Neoplasms: Systemic Therapy - Biotherapy and Novel Targeted Agents

(2017) Marianne Pavel et al.   NEUROENDOCRINOLOGY

Antisecretory Effects of Chimeric Somatostatin/Dopamine Receptor Ligands on Gastroenteropancreatic Neuroendocrine Tumors

(2017) Anne Couvelard et al.   PANCREAS

Investigation of Drug Cocktail Effects on Cancer Cell-Spheroids Using a Microfluidic Drug-Screening Assay

(2017) Ka Au Ieong et al.   Micromachines

Trends in the Incidence, Prevalence, and Survival Outcomes in Patients With Neuroendocrine Tumors in the United States

(2017) Arvind Dasari et al.   JAMA Oncology

Fatty acids rather than hormones restore in vitro angiogenesis in human male and female endothelial cells cultured in charcoal-stripped serum

(2017) Claudia Vanetti et al.   PLoS One

3D tumor spheroids: an overview on the tools and techniques used for their analysis

(2016) Elisabete C. Costa et al.   BIOTECHNOLOGY ADVANCES

Hormone-deprived serum impairs angiogenic properties in human endothelial cells regardless of estrogens

(2016) Claudia Vanetti et al.   ENDOCRINE RESEARCH

The epidemiology of metastases in neuroendocrine tumors

(2016) Matias Riihimäki et al.   INTERNATIONAL JOURNAL OF CANCER

Effects of Somatostatin Analogs and Dopamine Agonists on Insulin-Like Growth Factor 2-Induced Insulin Receptor Isoform A Activation by Gastroenteropancreatic Neuroendocrine Tumor Cells

(2016) Roxanne C.S. van Adrichem et al.   NEUROENDOCRINOLOGY

ENETS Consensus Guidelines Update for the Management of Patients with Functional Pancreatic Neuroendocrine Tumors and Non-Functional Pancreatic Neuroendocrine Tumors

(2016) M. Falconi et al.   NEUROENDOCRINOLOGY

ENETS Consensus Guidelines Update for the Management of Distant Metastatic Disease of Intestinal, Pancreatic, Bronchial Neuroendocrine Neoplasms (NEN) and NEN of Unknown Primary Site

(2016) M. Pavel et al.   NEUROENDOCRINOLOGY

ENETS Consensus Guidelines Update for Neuroendocrine Neoplasms of the Jejunum and Ileum

(2016) B. Niederle et al.   NEUROENDOCRINOLOGY

Spheroid-based 3-dimensional culture models: Gene expression and functionality in head and neck cancer

(2016) MARIANNE SCHMIDT et al.   ONCOLOGY REPORTS

Expression of Somatostatin Receptors 1-5 and Dopamine Receptor 2 in Lung Carcinoids: Implications for a Therapeutic Role

(2015) George Kanakis et al.   NEUROENDOCRINOLOGY

Association of dose escalation of octreotide long-acting release on clinical symptoms and tumor markers and response among patients with neuroendocrine tumors

(2015) Khalid Al-Efraij et al.   Cancer Medicine

Three-Dimensional Cell Culture Systems and Their Applications in Drug Discovery and Cell-Based Biosensors

(2014) Rasheena Edmondson et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Optimization of liquid overlay technique to formulate heterogenic 3D co-cultures models

(2014) Elisabete C. Costa et al.   BIOTECHNOLOGY AND BIOENGINEERING

Development of an Innovative 3D Cell Culture System to Study Tumour - Stroma Interactions in Non-Small Cell Lung Cancer Cells

(2014) Arno Amann et al.   PLoS One

Colon cancer cells adopt an invasive phenotype without mesenchymal transition in 3-D but not 2-D culture upon combined stimulation with EGF and crypt growth factors

(2013) Kirsten Ludwig et al.   BMC CANCER

Targeting the somatostatin receptor in pituitary and neuroendocrine tumors

(2013) Marije J Veenstra et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Serotonin promotes the proliferation of serum-deprived hepatocellular carcinoma cells via upregulation of FOXO3a

(2013) Chao Liang et al.   Molecular Cancer

Development of a human three-dimensional organotypic skin-melanoma spheroid model for in vitro drug testing

(2013) H Vörsmann et al.   Cell Death & Disease

Multicellular tumor spheroid model to evaluate spatio-temporal dynamics effect of chemotherapeutics: application to the gemcitabine/CHK1 inhibitor combination in pancreatic cancer

(2012) Isabelle Dufau et al.   BMC CANCER

Three-dimensional cell culture: the missing link in drug discovery

(2012) Susan Breslin et al.   DRUG DISCOVERY TODAY

Deconstructing the third dimension – how 3D culture microenvironments alter cellular cues

(2012) Brendon M. Baker et al.   JOURNAL OF CELL SCIENCE

Opportunities and challenges for use of tumor spheroids as models to test drug delivery and efficacy

(2012) Geeta Mehta et al.   JOURNAL OF CONTROLLED RELEASE

The role of somatostatin and dopamine D2 receptors in endocrine tumors

(2011) Federico Gatto et al.   ENDOCRINE-RELATED CANCER

Somatostatin-Dopamine Chimeras: A Novel Approach to Treatment of Neuroendocrine Tumors

(2011) M. Culler   HORMONE AND METABOLIC RESEARCH

In vitro three-dimensional (3D) models in cancer research: An update

(2011) Lauren C. Kimlin et al.   MOLECULAR CARCINOGENESIS

Retaining cell-cell contact enables preparation and culture of spheroids composed of pure primary cancer cells from colorectal cancer

(2011) J. Kondo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cabergoline monotherapy in the long-term treatment of Cushing's disease

(2010) Ariane Godbout et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Profiling of Somatostatin Receptor Subtype Expression by Quantitative PCR and Correlation With Clinicopathological Features in Pancreatic Endocrine Tumors

(2010) Yoshihito Nakayama et al.   PANCREAS

A Comprehensive Panel of Three-Dimensional Models for Studies of Prostate Cancer Growth, Invasion and Drug Responses

(2010) Ville Härmä et al.   PLoS One

ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Tumors: Biochemical Markers

(2009) Dermot O’Toole et al.   NEUROENDOCRINOLOGY

Differential cytotoxicity of novel somatostatin and dopamine chimeric compounds on bronchopulmonary and small intestinal neuroendocrine tumor cell lines

(2008) Mark Kidd et al.   CANCER

Gastroenteropancreatic neuroendocrine tumours

(2008) Irvin M Modlin et al.   LANCET ONCOLOGY

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols