Senataxin homologue Sen1 is required for efficient termination of RNA polymerase III transcription

Mfd Dynamically Regulates Transcription via a Release and Catch-Up Mechanism

(2018) Tung T. Le et al.   CELL

The Affinity of the S9.6 Antibody for Double-Stranded RNAs Impacts the Accurate Mapping of R-Loops in Fission Yeast

(2018) Stella R. Hartono et al.   JOURNAL OF MOLECULAR BIOLOGY

A senataxin-associated exonuclease SAN1 is required for resistance to DNA interstrand cross-links

(2018) Alex M. Andrews et al.   Nature Communications

Senataxin resolves RNA:DNA hybrids forming at DNA double-strand breaks to prevent translocations

(2018) Sarah Cohen et al.   Nature Communications

The epiGenomic Efficient Correlator (epiGeEC) tool allows fast comparison of user datasets with thousands of public epigenomic datasets

(2018) Jonathan Laperle et al.   BIOINFORMATICS

Common mechanism of transcription termination at coding and noncoding RNA genes in fission yeast

(2018) Marc Larochelle et al.   Nature Communications

Senataxin: Genome Guardian at the Interface of Transcription and Neurodegeneration

(2017) Matthias Groh et al.   JOURNAL OF MOLECULAR BIOLOGY

R-ChIP Using Inactive RNase H Reveals Dynamic Coupling of R-loops with Transcriptional Pausing at Gene Promoters

(2017) Liang Chen et al.   MOLECULAR CELL

Dormant origins and fork protection mechanisms rescue sister forks arrested by transcription

(2017) Alessandra Brambati et al.   NUCLEIC ACIDS RESEARCH

Strong transcription blockage mediated by R-loop formation within a G-rich homopurine–homopyrimidine sequence localized in the vicinity of the promoter

(2017) Boris P. Belotserkovskii et al.   NUCLEIC ACIDS RESEARCH

Transcription by RNA polymerase III: insights into mechanism and regulation

(2016) Tomasz W. Turowski et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The Nrd1-like protein Seb1 coordinates cotranscriptional 3′ end processing and polyadenylation site selection

(2016) Jean-François Lemay et al.   GENES & DEVELOPMENT

Global analysis of transcriptionally engaged yeast RNA polymerase III reveals extended tRNA transcripts

(2016) Tomasz W. Turowski et al.   GENOME RESEARCH

Sen1, the yeast homolog of human senataxin, plays a more direct role than Rad26 in transcription coupled DNA repair

(2016) Wentao Li et al.   NUCLEIC ACIDS RESEARCH

Biochemical characterization of the helicase Sen1 provides new insights into the mechanisms of non-coding transcription termination

(2016) Zhong Han et al.   NUCLEIC ACIDS RESEARCH

Saccharomyces cerevisiaeSen1 Helicase Domain Exhibits 5′- to 3′-Helicase Activity with a Preference for Translocation on DNA Rather than RNA

(2015) Stephen Martin-Tumasz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination

(2015) Dorothy Yanling Zhao et al.   NATURE

Senataxin suppresses the antiviral transcriptional response and controls viral biogenesis

(2015) Matthew S Miller et al.   NATURE IMMUNOLOGY

Efficient and quantitative high-throughput tRNA sequencing

(2015) Guanqun Zheng et al.   NATURE METHODS

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

An optimized kit-free method for making strand-specific deep sequencing libraries from RNA fragments

(2014) Erin E. Heyer et al.   NUCLEIC ACIDS RESEARCH

VAP: a versatile aggregate profiler for efficient genome-wide data representation and discovery

(2014) C. Coulombe et al.   NUCLEIC ACIDS RESEARCH

RNA Processing Factors Swd2.2 and Sen1 Antagonize RNA Pol III-Dependent Transcription and the Localization of Condensin at Pol III Genes

(2014) Pénélope Legros et al.   PLoS Genetics

Genome-Wide Distribution of RNA-DNA Hybrids Identifies RNase H Targets in tRNA Genes, Retrotransposons and Mitochondria

(2014) Aziz El Hage et al.   PLoS Genetics

A proteome-wide visual screen identifies fission yeast proteins localizing to DNA double-strand breaks

(2013) Yang Yu et al.   DNA REPAIR

A SUMO-dependent interaction between Senataxin and the exosome, disrupted in the neurodegenerative disease AOA2, targets the exosome to sites of transcription-induced DNA damage

(2013) P. Richard et al.   GENES & DEVELOPMENT

A bacterial-like mechanism for transcription termination by the Sen1p helicase in budding yeast

(2013) Odil Porrua et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Software for Computing and Annotating Genomic Ranges

(2013) Michael Lawrence et al.   PLoS Computational Biology

Transcription termination by the eukaryotic RNA polymerase III

(2012) Aneeshkumar G. Arimbasseri et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Senataxin Associates with Replication Forks to Protect Fork Integrity across RNA-Polymerase-II-Transcribed Genes

(2012) Amaya Alzu et al.   CELL

Senataxin, Defective in the Neurodegenerative Disorder Ataxia with Oculomotor Apraxia 2, Lies at the Interface of Transcription and the DNA Damage Response

(2012) O. Yuce et al.   MOLECULAR AND CELLULAR BIOLOGY

Transcriptome-wide Analysis of Exosome Targets

(2012) Claudia Schneider et al.   MOLECULAR CELL

Extensive Degradation of RNA Precursors by the Exosome in Wild-Type Cells

(2012) Rajani Kanth Gudipati et al.   MOLECULAR CELL

Kinetic Competition between RNA Polymerase II and Sen1-Dependent Transcription Termination

(2012) Dane Z. Hazelbaker et al.   MOLECULAR CELL

RNA polymerase III mutants in TFIIFα-like C37 that cause terminator readthrough with no decrease in transcription output

(2012) Keshab Rijal et al.   NUCLEIC ACIDS RESEARCH

Yeast Sen1 Helicase Protects the Genome from Transcription-Associated Instability

(2011) Hannah E. Mischo et al.   MOLECULAR CELL

Human Senataxin Resolves RNA/DNA Hybrids Formed at Transcriptional Pause Sites to Promote Xrn2-Dependent Termination

(2011) Konstantina Skourti-Stathaki et al.   MOLECULAR CELL

Point mutations in the Rpb9-homologous domain of Rpc11 that impair transcription termination by RNA polymerase III

(2011) J. R. Iben et al.   NUCLEIC ACIDS RESEARCH

Widespread occurrence of non-canonical transcription termination by human RNA polymerase III

(2011) Andrea Orioli et al.   NUCLEIC ACIDS RESEARCH

Fast and accurate long-read alignment with Burrows–Wheeler transform

(2010) Heng Li et al.   BIOINFORMATICS

BEDTools: a flexible suite of utilities for comparing genomic features

(2010) Aaron R. Quinlan et al.   BIOINFORMATICS

Functional role for senataxin, defective in ataxia oculomotor apraxia type 2, in transcriptional regulation

(2009) Amila Suraweera et al.   HUMAN MOLECULAR GENETICS

The UCSC Genome Browser database: update 2010

(2009) B. Rhead et al.   NUCLEIC ACIDS RESEARCH

Budding yeast RNA polymerases I and II employ parallel mechanisms of transcriptional termination

(2008) J. Kawauchi et al.   GENES & DEVELOPMENT