Threonine aldolases: perspectives in engineering and screening the enzymes with enhanced substrate and stereo specificities

Development of a growth-dependent selection system for identification of l-threonine aldolases

(2015) Dalia Bulut et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Molecular basis of E. coli l-threonine aldolase catalytic inactivation at low pH

(2015) Soumya G. Remesh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Improving thermal stability of thermophilic l -threonine aldolase from Thermotoga maritima

(2015) Lukasz Wieteska et al.   JOURNAL OF BIOTECHNOLOGY

Evolution of Threonine Aldolases, a Diverse Family Involved in the Second Pathway of Glycine Biosynthesis

(2015) Guangxiu Liu et al.   JOURNAL OF MOLECULAR EVOLUTION

Development of a Two-Step, Enantioselective Synthesis of an Amino Alcohol Drug Candidate

(2015) Michael A. Schmidt et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Preparation of β-hydroxy-α-amino Acid Using Recombinant d-Threonine Aldolase

(2015) Steven L. Goldberg et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

The Crystal Structure of D-Threonine Aldolase from Alcaligenes xylosoxidans Provides Insight into a Metal Ion Assisted PLP-Dependent Mechanism

(2015) Michael K. Uhl et al.   PLoS One

Sequential Biocatalytic Aldol Reactions in Multistep Asymmetric Synthesis: Pipecolic Acid, Piperidine and Pyrrolidine (Homo)Iminocyclitol Derivatives from Achiral Building Blocks

(2014) Anna Soler et al.   ADVANCED SYNTHESIS & CATALYSIS

Cover Picture: Excellent Stability of a Lithium-Ion-Conducting Solid Electrolyte upon Reversible Li+/H+Exchange in Aqueous Solutions (Angew. Chem. Int. Ed. 1/2015)

(2014) Cheng Ma et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A fast and sensitive coupled enzyme assay for the measurement of l-threonine and application to high-throughput screening of threonine-overproducing strains

(2014) Yongfei Liu et al.   ENZYME AND MICROBIAL TECHNOLOGY

Dry entrapment of enzymes by epoxy or polyester resins hardened on different solid supports

(2014) Susann Barig et al.   ENZYME AND MICROBIAL TECHNOLOGY

Production and properties of threonine aldolase immobilisates

(2014) Sandra Kurjatschij et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

 L-allo-Threonine aldolase with an H128Y/S292R mutation fromAeromonas jandaeiDK-39 reveals the structural basis of changes in substrate stereoselectivity

(2014) Hui-Min Qin et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Flow synthesis of phenylserine using threonine aldolase immobilized on Eupergit support

(2013) Jagdish D Tibhe et al.   Beilstein Journal of Organic Chemistry

Biocatalytic Methods for CC Bond Formation

(2013) Kateryna Fesko et al.   ChemCatChem

Strategies for the discovery and engineering of enzymes for biocatalysis

(2013) Timo Davids et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

On the catalytic mechanism and stereospecificity ofEscherichia colil-threonine aldolase

(2013) Martino L. di Salvo et al.   FEBS Journal

Threonine aldolase immobilization on different supports for engineering of productive, cost-efficient enzymatic microreactors

(2012) H. Fu et al.   CHEMICAL ENGINEERING JOURNAL

OPTIMAL PRODUCTION OF L-threo-2,3-DIHYDROXYPHENYLSERINE (L-threo-DOPS) ON A LARGE SCALE BY DIASTEREOSELECTIVITY-ENHANCED VARIANT OF L-THREONINE ALDOLASE EXPRESSED INEscherichia coli

(2012) Hui-Jeong Gwon et al.   PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY

A novel genetic selection system for PLP-dependent threonine aldolases

(2012) Lars Giger et al.   TETRAHEDRON

COMPUTATIONAL TOOLS FOR RATIONAL PROTEIN ENGINEERING OF ALDOLASES

(2012) Michael Widmann et al.   Computational and Structural Biotechnology Journal

Investigation on the chemoenzymatic synthesis of threo- and erythro-β-hydroxy-l-glutamic acid derivatives

(2011) Francesca Sagui et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

A study towards efficient l-threonine aldolase-catalyzed enantio- and diastereoselective aldol reactions of glycine with substituted benzaldehydes: biocatalyst production and process development

(2011) Katrin Baer et al.   TETRAHEDRON-ASYMMETRY

Preparation of optically active β-hydroxy-α-amino acid by immobilized Escherichia coli cells with serine hydroxymethyl transferase activity

(2010) Gen-Hai Zhao et al.   AMINO ACIDS

Threonine aldolases—screening, properties and applications in the synthesis of non-proteinogenic β-hydroxy-α-amino acids

(2010) Nina Dückers et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Expanding the Application Range of Aldolases: Novel Asymmetric Syntheses of α-Methylated β-Hydroxy α-Amino Acids and β-Amino Alcohols

(2010) Katrin Baer et al.   ChemCatChem

Biocatalytic Access to α,α-Dialkyl-α-amino Acids by a Mechanism-Based Approach

(2009) Kateryna Fesko et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Diastereoselective synthesis of l-threo-3,4-dihydroxyphenylserine by low-specific l-threonine aldolase mutants

(2009) Hui-Jeong Gwon et al.   BIOTECHNOLOGY LETTERS

Serine Hydroxymethyl Transferase fromStreptococcus thermophilus andL-Threonine Aldolase fromEscherichia coli as Stereocomplementary Biocatalysts for the Synthesis of β-Hydroxy-α,ω-diamino Acid Derivatives

(2008) Mariana L. Gutierrez et al.   CHEMISTRY-A EUROPEAN JOURNAL

Four types of threonine aldolases: Similarities and differences in kinetics/thermodynamics

(2007) Kateryna Fesko et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC