Crystal structure and characterization of esterase Est25 mutants reveal improved enantioselectivity toward (S)-ketoprofen ethyl ester
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Crystal structure and characterization of esterase Est25 mutants reveal improved enantioselectivity toward (S)-ketoprofen ethyl ester
Authors
Keywords
Esterase, Enzyme catalysis, Enantioselectivity, Crystal structure, X-ray crystallography
Journal
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
Volume 101, Issue 6, Pages 2333-2342
Publisher
Springer Nature
Online
2016-12-03
DOI
10.1007/s00253-016-7989-3
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Improved enantioselectivity of thermostable esterase from Archaeoglobus fulgidus toward (S)-ketoprofen ethyl ester by directed evolution and characterization of mutant esterases
- (2015) Jinyeong Kim et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Towards a green enantiomeric esterification of R/S-ketoprofen: A theoretical and experimental investigation
- (2015) María Victoria Toledo et al. JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
- Cloning and characterization of a novel thermostable esterase from Bacillus gelatini KACC 12197
- (2015) Jinyeong Kim et al. PROTEIN EXPRESSION AND PURIFICATION
- Engineering Enzyme Stability and Resistance to an Organic Cosolvent by Modification of Residues in the Access Tunnel
- (2013) Tana Koudelakova et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Characterization and molecular modelling of an engineered organic solvent tolerant, thermostable lipase with enhanced enzyme activity
- (2013) Rakesh Kumar et al. JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
- Improving the enantioselectivity of an esterase toward (S)-ketoprofen ethyl ester through protein engineering
- (2013) Sangyoung Yoon et al. JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
- Enhanced enantioselectivity of a carboxyl esterase from Rhodobacter sphaeroides by directed evolution
- (2012) Jingbo Ma et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Toward a Molecular Understanding of Protein Solubility: Increased Negative Surface Charge Correlates with Increased Solubility
- (2012) Ryan M. Kramer et al. BIOPHYSICAL JOURNAL
- Characterization of a new thermophilic and acid tolerant esterase from Thermotoga maritima capable of hydrolytic resolution of racemic ketoprofen ethyl ester
- (2012) Wei Tao et al. JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
- SwissDock, a protein-small molecule docking web service based on EADock DSS
- (2011) A. Grosdidier et al. NUCLEIC ACIDS RESEARCH
- Features and development ofCoot
- (2010) P. Emsley et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- PHENIX: a comprehensive Python-based system for macromolecular structure solution
- (2010) Paul D. Adams et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Role of bicontinuous microemulsion in the rapid enzymatic hydrolysis of (R,S)-ketoprofen ethyl ester in a micro-reactor
- (2010) M. Sathishkumar et al. BIORESOURCE TECHNOLOGY
- Stability effects of mutations and protein evolvability
- (2009) Nobuhiko Tokuriki et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Cloning and characterization of thermostable esterase from Archaeoglobus fulgidus
- (2008) Seung-Bum Kim et al. JOURNAL OF MICROBIOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation