The proposed systemic thermogenic metabolites succinate and 12,13-diHOME are inversely associated with adiposity and related metabolic traits: evidence from a large human cross-sectional study

12,13-diHOME: An Exercise-Induced Lipokine that Increases Skeletal Muscle Fatty Acid Uptake

(2018) Kristin I. Stanford et al.   Cell Metabolism

Elevated circulating levels of succinate in human obesity are linked to specific gut microbiota

(2018) Carolina Serena et al.   ISME Journal

Gut-brain signaling in energy homeostasis: the unexpected role of microbiota-derived succinate

(2018) Filipe de Vadder et al.   JOURNAL OF ENDOCRINOLOGY

The MR-Base platform supports systematic causal inference across the human phenome

(2018) Gibran Hemani et al.   eLife

Meta-analysis of genome-wide association studies for height and body mass index in ∼700000 individuals of European ancestry

(2018) Loic Yengo et al.   HUMAN MOLECULAR GENETICS

Accumulation of succinate controls activation of adipose tissue thermogenesis

(2018) Evanna L. Mills et al.   NATURE

Cohort Profile: The Oxford Biobank

(2017) Fredrik Karpe et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Glucose feeds the TCA cycle via circulating lactate

(2017) Sheng Hui et al.   NATURE

The cold-induced lipokine 12,13-diHOME promotes fatty acid transport into brown adipose tissue

(2017) Matthew D Lynes et al.   NATURE MEDICINE

Impact of fat mass and distribution on lipid turnover in human adipose tissue

(2017) Kirsty L. Spalding et al.   Nature Communications

Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator

(2016) Jack Bowden et al.   GENETIC EPIDEMIOLOGY

Neonatal gut microbiota associates with childhood multisensitized atopy and T cell differentiation

(2016) Kei E Fujimura et al.   NATURE MEDICINE

Activation of Human Brown Adipose Tissue by a β3-Adrenergic Receptor Agonist

(2015) Aaron M. Cypess et al.   Cell Metabolism

Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression

(2015) J. Bowden et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development

(2015) Jimmy F. P. Berbée et al.   Nature Communications

Temperature-Acclimated Brown Adipose Tissue Modulates Insulin Sensitivity in Humans

(2014) Paul Lee et al.   DIABETES

Modulation of blood oxylipin levels by long-chain omega-3 fatty acid supplementation in hyper- and normolipidemic men

(2014) Jan Philipp Schuchardt et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Recruited brown adipose tissue as an antiobesity agent in humans

(2013) Takeshi Yoneshiro et al.   JOURNAL OF CLINICAL INVESTIGATION

Cold acclimation recruits human brown fat and increases nonshivering thermogenesis

(2013) Anouk A.J.J. van der Lans et al.   JOURNAL OF CLINICAL INVESTIGATION

Discovery and refinement of loci associated with lipid levels

(2013) Cristen J Willer et al.   NATURE GENETICS

Brown adipose tissue regulates glucose homeostasis and insulin sensitivity

(2012) Kristin I. Stanford et al.   JOURNAL OF CLINICAL INVESTIGATION

Method based on GC–MS to study the influence of tricarboxylic acid cycle metabolites on cardiovascular risk factors

(2012) M. Calderón-Santiago et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Cold but not sympathomimetics activates human brown adipose tissue in vivo

(2012) A. M. Cypess et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Brown adipose tissue activity controls triglyceride clearance

(2011) Alexander Bartelt et al.   NATURE MEDICINE

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

(2010) Josée Dupuis et al.   NATURE GENETICS

High Incidence of Metabolically Active Brown Adipose Tissue in Healthy Adult Humans: Effects of Cold Exposure and Adiposity

(2009) M. Saito et al.   DIABETES

Identification and Importance of Brown Adipose Tissue in Adult Humans

(2009) Aaron M. Cypess et al.   NEW ENGLAND JOURNAL OF MEDICINE

Comparing Algorithms for Genotype Imputation

(2008) Jonathan Marchini et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Anatomical Profiling of G Protein-Coupled Receptor Expression

(2008) Jean B. Regard et al.   CELL