Polyketides in Aspergillus terreus: biosynthesis pathway discovery and application

Biosynthesis of LL-Z1272β: Discovery of a New Member of NRPS-like Enzymes for Aryl-Aldehyde Formation

(2016) Chang Li et al.   CHEMBIOCHEM

Marine natural products

(2016) John W. Blunt et al.   NATURAL PRODUCT REPORTS

Biosynthetic Pathway of the Reduced Polyketide Product Citreoviridin in Aspergillus terreus var. aureus Revealed by Heterologous Expression in Aspergillus nidulans

(2016) Tzu-Shyang Lin et al.   ORGANIC LETTERS

Elucidation of cladofulvin biosynthesis reveals a cytochrome P450 monooxygenase required for anthraquinone dimerization

(2016) Scott Griffiths et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Improving the yield of (+)-terrein from the salt-tolerant Aspergillus terreus PT06-2

(2016) Chengying Zhao et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

The molecular steps of citrinin biosynthesis in fungi

(2016) Yi He et al.   Chemical Science

Effects of Lovastatin on MDA-MB-231 Breast Cancer Cells: An Antibody Microarray Analysis

(2016) Tao Yang et al.   Journal of Cancer

Induction of secondary metabolism of Aspergillus terreus ATCC 20542 in the batch bioreactor cultures

(2015) Tomasz Boruta et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Lovastatin and (+)-geodin production byAspergillus terreusfrom crude glycerol

(2015) Muhamad Hafiz Abd Rahim et al.   ENGINEERING IN LIFE SCIENCES

Uncovering the Unusual D-Ring Construction in Terretonin Biosynthesis by Collaboration of a Multifunctional Cytochrome P450 and a Unique Isomerase

(2015) Yudai Matsuda et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Modification of artificial sea water for the mass production of (+)-terrein byAspergillus terreusstrain PF26 derived from marine spongePhakellia fusca

(2015) Y. Yin et al.   LETTERS IN APPLIED MICROBIOLOGY

Phytotoxin production in Aspergillus terreus is regulated by independent environmental signals

(2015) Markus Gressler et al.   eLife

A new high-performance heterologous fungal expression system based on regulatory elements from the Aspergillus terreus terrein gene cluster

(2015) Markus Gressler et al.   Frontiers in Microbiology

Terrein Biosynthesis in Aspergillus terreus and Its Impact on Phytotoxicity

(2014) Christoph Zaehle et al.   CHEMISTRY & BIOLOGY

Aryl-aldehyde Formation in Fungal Polyketides: Discovery and Characterization of a Distinct Biosynthetic Mechanism

(2014) Meng Wang et al.   CHEMISTRY & BIOLOGY

Culture-based and sequence-based insights into biosynthesis of secondary metabolites by Aspergillus terreus ATCC 20542

(2014) Tomasz Boruta et al.   JOURNAL OF BIOTECHNOLOGY

Monascus azaphilone pigment biosynthesis employs a dedicated fatty acid synthase for short chain fatty acyl moieties

(2014) Bijinu Balakrishnan et al.   Journal of the Korean Society for Applied Biological Chemistry

Marine Microorganism-Invertebrate Assemblages: Perspectives to Solve the “Supply Problem” in the Initial Steps of Drug Discovery

(2014) Miguel Leal et al.   Marine Drugs

The role of distant mutations and allosteric regulation on LovD active site dynamics

(2014) Gonzalo Jiménez-Osés et al.   Nature Chemical Biology

Molecular Genetic Characterization of Terreic Acid Pathway in Aspergillus terreus

(2014) Chun-Jun Guo et al.   ORGANIC LETTERS

Characterization and Engineering of the Adenylation Domain of a NRPS-Like Protein: A Potential Biocatalyst for Aldehyde Generation

(2014) Meng Wang et al.   ACS Catalysis

Genetic localization and in vivo characterization of a Monascus azaphilone pigment biosynthetic gene cluster

(2013) Bijinu Balakrishnan et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

An Efficient System for Heterologous Expression of Secondary Metabolite Genes in Aspergillus nidulans

(2013) Yi-Ming Chiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Genetic manipulation of longevity-related genes as a tool to regulate yeast life span and metabolite production during winemaking

(2013) Helena Orozco et al.   Microbial Cell Factories

Heterologous Reconstitution of the Intact Geodin Gene Cluster in Aspergillus nidulans through a Simple and Versatile PCR Based Approach

(2013) Morten Thrane Nielsen et al.   PLoS One

Enhanced production of (+)-terrein by Aspergillus terreus strain PF26 with epigenetic modifier suberoylanilide hydroxamic acid

(2013) Lan Xiao et al.   PROCESS BIOCHEMISTRY

Oxidative dearomatisation: the key step of sorbicillinoid biosynthesis

(2013) Ahmed al Fahad et al.   Chemical Science

Ectopic ATP synthase facilitates transfer of HIV-1 from antigen-presenting cells to CD4+ target cells

(2012) A. Yavlovich et al.   BLOOD

Ectopic ATP Synthase Blockade Suppresses Lung Adenocarcinoma Growth by Activating the Unfolded Protein Response

(2012) H.-Y. Chang et al.   CANCER RESEARCH

Identification of a Key Prenyltransferase Involved in Biosynthesis of the Most Abundant Fungal Meroterpenoids Derived from 3,5-Dimethylorsellinic Acid.

(2012) Takayuki Itoh et al.   CHEMBIOCHEM

Terretonin Biosynthesis Requires Methylation as Essential Step for Cyclization

(2012) Yudai Matsuda et al.   CHEMBIOCHEM

Characterization of a Silent Azaphilone Gene Cluster from Aspergillus niger ATCC 1015 Reveals a Hydroxylation-Mediated Pyran-Ring Formation

(2012) Angelica O. Zabala et al.   CHEMISTRY & BIOLOGY

Secretome of Aspergillus oryzae in Shaoxing rice wine koji

(2012) Bo Zhang et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Pre-SMTP, a key precursor for the biosynthesis of the SMTP plasminogen modulators

(2012) Yuuichi Nishimura et al.   JOURNAL OF ANTIBIOTICS

Asperjinone, a Nor-Neolignan, and Terrein, a Suppressor of ABCG2-Expressing Breast Cancer Cells, from Thermophilic Aspergillus terreus

(2012) Wen-Ying Liao et al.   JOURNAL OF NATURAL PRODUCTS

Navigating the Fungal Polyketide Chemical Space: From Genes to Molecules

(2012) Yit-Heng Chooi et al.   JOURNAL OF ORGANIC CHEMISTRY

Two Separate Gene Clusters Encode the Biosynthetic Pathway for the Meroterpenoids Austinol and Dehydroaustinol in Aspergillus nidulans

(2012) Hsien-Chun Lo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Illuminating the Diversity of Aromatic Polyketide Synthases in Aspergillus nidulans

(2012) Manmeet Ahuja et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Molecular Genetic Characterization of a Cluster in A. terreus for Biosynthesis of the Meroterpenoid Terretonin

(2012) Chun-Jun Guo et al.   ORGANIC LETTERS

Genetic, molecular, and biochemical basis of fungal tropolone biosynthesis

(2012) J. Davison et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Medium optimization for the high yield production of single (+)-terrein by Aspergillus terreus strain PF26 derived from marine sponge Phakellia fusca

(2012) Ying Yin et al.   PROCESS BIOCHEMISTRY

Enhanced production of (+)-terrein in fed-batch cultivation of Aspergillus terreus strain PF26 with sodium citrate

(2012) Ying Yin et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

Cyclosporin A — A review on fermentative production, downstream processing and pharmacological applications

(2011) Shrikant A. Survase et al.   BIOTECHNOLOGY ADVANCES

Studies on screening of higher γ-aminobutyric acid-producing Monascus and optimization of fermentative parameters

(2011) Donghua Jiang et al.   EUROPEAN FOOD RESEARCH AND TECHNOLOGY

Characterization of the Aspergillus nidulans Monodictyphenone Gene Cluster

(2010) Y.-M. Chiang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Unraveling polyketide synthesis in members of the genus Aspergillus

(2010) Yi-Ming Chiang et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Asperfuranone from Aspergillus nidulans Inhibits Proliferation of Human Non-Small Cell Lung Cancer A549 Cells via Blocking Cell Cycle Progression and Inducing Apoptosis

(2010) Clay C. C. Wang et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

The Fungal Product Terreic Acid Is a Covalent Inhibitor of the Bacterial Cell Wall Biosynthetic Enzyme UDP-N-Acetylglucosamine 1-Carboxyvinyltransferase (MurA),

(2010) Huijong Han et al.   BIOCHEMISTRY

Biosynthesis of lovastatin and related metabolites formed by fungal iterative PKS enzymes

(2010) Chantel D. Campbell et al.   BIOPOLYMERS

SMURF: Genomic mapping of fungal secondary metabolite clusters

(2010) Nora Khaldi et al.   FUNGAL GENETICS AND BIOLOGY

Chemistry and Biology of Mycotoxins and Related Fungal Metabolites

(2009) Stefan Bräse et al.   CHEMICAL REVIEWS

Physically Discrete β-Lactamase-Type Thioesterase Catalyzes Product Release in Atrochrysone Synthesis by Iterative Type I Polyketide Synthase

(2009) Takayoshi Awakawa et al.   CHEMISTRY & BIOLOGY

Bruton's tyrosine kinase as a drug discovery target

(2009) Z. Pan   DRUG NEWS & PERSPECTIVES

A New Terrein Glucoside, a Novel Inhibitor of Angiogenin Secretion in Tumor Angiogenesis

(2009) Masayuki Arakawa et al.   JOURNAL OF ANTIBIOTICS

A Gene Cluster Containing Two Fungal Polyketide Synthases Encodes the Biosynthetic Pathway for a Polyketide, Asperfuranone, inAspergillus nidulans

(2009) Yi-Ming Chiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Aurovertins F–H from the Entomopathogenic FungusMetarhizium anisopliae(1)

(2008) Miwa Azumi et al.   JOURNAL OF NATURAL PRODUCTS