Article
Chemistry, Organic
Oleg Szumski, Joy Karmakar, Flavio Grynszpan
Summary: The study describes a fast method for preparing symmetric and asymmetric α-bimane derivatives, which is then applied to synthesize ethynylbenzaldehyde bearing bimanes as potential selective probes for aldolase class I enzymes.
Article
Chemistry, Inorganic & Nuclear
Montserrat Ferrer, Albert Gallen, Manuel Martinez, Merce Rocamora, Rakesh Puttreddy, Kari Rissanen
Summary: New chiral tetranuclear square-like homo- and hetero-metallamacrocycles containing allyl-palladium and optically pure moieties have been successfully synthesized. The structures have been characterized by multinuclear NMR spectroscopy and MS spectrometry. XRD analysis confirms the structural characteristics of the new metallamacrocycles. These architectures have shown catalytic activity in asymmetric allylic alkylation reaction.
DALTON TRANSACTIONS
(2022)
Article
Chemistry, Multidisciplinary
Gabrielle A. Leith, Natalia B. Shustova
Summary: This Feature Article reviews the advances in fulleretic materials over the past five years, highlighting the benefits of combining the intriguing characteristics of fulleretic molecules with hierarchical materials. The focus is on the recent trends in designing fulleretic compounds and understanding their properties, enriching the repertoire of carbon-rich functional materials.
CHEMICAL COMMUNICATIONS
(2021)
Article
Chemistry, Physical
Jonathan Cisterna, Mauricio Fuentealba, Carolina Manzur, David Carrillo
Summary: This paper presents a new type of asymmetrical Fe(III) complex, which contains two different ligands in the equatorial and axial positions, showing potential as a building block for dipolar D-pi-A systems in the field of optoelectronic devices. The compound features a distorted square base pyramid geometry and centrosymmetric crystal packing, providing insights for the construction of novel compounds in the field of optoelectronic devices.
JOURNAL OF MOLECULAR STRUCTURE
(2021)
Article
Chemistry, Multidisciplinary
Alexey N. Bilyachenko, Grigorii S. Astakhov, Alena N. Kulakova, Alexander A. Korlyukov, Yan V. Zubavichus, Pavel V. Dorovatovskii, Lidia S. Shul'pina, Elena S. Shubina, Nikolay S. Ikonnikov, Marina V. Kirillova, Anna Y. Zueva, Alexander M. Kirillov, Georgiy B. Shul'pin
Summary: This study describes a series of heterometallic silsesquioxane coordination polymers using silsesquioxane derivatives as important organosilicon building blocks. These coordination polymers have unique structural and functional characteristics and were assembled using coppersilsesquioxane cages and large cesium or rubidium cations. The resulting 1D, 2D, or 3D coordination polymer architectures exhibit tightly connected nonporous structures with metallocene Cs... π (Rb... π) joints.
CRYSTAL GROWTH & DESIGN
(2022)
Review
Chemistry, Physical
Nilanjana Majumdar
Summary: Catalytic asymmetric transformation is a powerful strategy for synthesizing diverse nonracemic molecular entities. Carboxylic acids have been explored as building blocks in this area, and significant advancements have been made in the last three decades. They can act as both C- and O-nucleophiles, as well as electrophiles, in asymmetric reactions under catalytic conditions.
Article
Chemistry, Multidisciplinary
Chunlei Zhang, Guangyu Chu, Zesong Ruan, Ning Tang, Cunfeng Song, Qichao Li, Wenjie Zhou, Jiale Jin, Hossam Haick, Yunfeng Chen, Daxiang Cui
Summary: By combining metal-organic coordination interactions, engineers have successfully constructed functional films on the surface of titanium implants with structural color and antibacterial activity. These films have high mechanical stability, hydrophilicity, and promote the formation of hydroxyapatite, improving the physicochemical properties of the bone-implant interface.
Article
Chemistry, Inorganic & Nuclear
Bi-Liu Lan, Ai-Yi Luo, Bing Shao, Li-Na Gao, Qin Wei, Yu-Ning Liang, Jin Huang, Zhong Zhang
Summary: By controlling reaction parameters, metal ligands and coordination polymers with different structures were successfully prepared. The study found that pH, ligand size, and metal type have significant influences on structural evolution.
DALTON TRANSACTIONS
(2022)
Article
Nanoscience & Nanotechnology
Lang Wang, Zhongmin Geng, Yannis Y. L. Ho, Jiayu Zhou, Nicola Judge, Yafei Li, Weiping Wang, Jinyao Liu, Yufeng Wang
Summary: By integrating metal-organic cage materials with amphiphilic block copolymers, a new type of composite micellar nanoparticles called block co-polyMOC micelles (BCPMMs) have been developed. These BCPMMs exhibit remarkable stability against dilution and have shown extended blood circulation, favorable biodistribution, and improved treatment efficacy when used as nanocarriers for anticancer drugs.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Nanoscience & Nanotechnology
Lang Wang, Zhongmin Geng, Yannis Y. L. Ho, Jiayu Zhou, Nicola Judge, Yafei Li, Weiping Wang, Jinyao Liu, Yufeng Wang
Summary: Metal-organic cage (MOC) materials are integrated with amphiphilic block copolymers (BCPs) to fabricate stable block co-polyMOC micellar nanoparticles (BCPMMs). BCPMMs exhibit extended blood circulation, favorable biodistribution, and improved treatment efficacy for anticancer drugs.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Chemistry, Inorganic & Nuclear
Jan Holub, Antonio Santoro, Mihail-Adrian Stadler, Jean-Marie Lehn
Summary: The sequential assembly of terminally functionalized bishydrazone ligands followed by coordination with Zn(ii) metal cations yields multi-functionalized grid-type complexes. The introduction of aldehyde functional groups results in octavalent grids, offering potential for diverse dynamic covalent decorations. Further connection with a difunctional covalent linker leads to folded molecular grids with double hairpins geometry, allowing for multifunctional dynamic covalent chemistry.
INORGANIC CHEMISTRY FRONTIERS
(2021)
Article
Chemistry, Multidisciplinary
Thais Grancha, Arnau Carne-Sanchez, Farnoosh Zarekarizi, Laura Hernandez-Lopez, Jorge Albalad, Akim Khobotov, Vincent Guillerm, Ali Morsali, Judith Juanhuix, Felipe Gandara, Inhar Imaz, Daniel Maspoch
Summary: This study demonstrates the use of polycarboxylate cuboctahedral Rh-II-MOPs as building blocks for highly-connected MOFs. Functionalized MOPs were linked with metallic SBUs to form bimetallic MOFs with ftw (4,12)-c or rht (3,24)-c topologies.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Materials Science, Multidisciplinary
Aislan Esmeraldo Paiva, Jhonattan Frank Baez Vasquez, Tatiana S. Perova, Fernanda G. L. Medeiros Borsagli, Michael Morris
Summary: This research focused on the selective metal infiltration of a pyridine-containing block copolymer in a liquid-phase setting. The study found that metal cations interact differently with the poly(2-vinylpyridine) component, and that the oxidation state and type of cation are crucial for the infiltration process, which is also influenced by the solvent used. While silver did not effectively infiltrate, nickel and chromium were able to reproduce the pattern of the block copolymer. These differences can be attributed to the coordination of pyridinic nitrogen and the metal, as well as p-interactions. Additionally, the presence of oxyanions enhanced the infiltration of chromium and facilitated the formation of a highly faithful ordered metal oxide layer.
Review
Chemistry, Inorganic & Nuclear
Eugenia Peresypkina, Alexander Virovets, Manfred Scheer
Summary: Complexes containing cyclo-P-n ligands can form coordination with metal atoms, leading to a wide range of self-assembled structures including polynuclear complexes, multidimensional coordination polymers, and giant supramolecules. Different coordination modes can be achieved based on the number and position of phosphorus atoms in the P-n ring, contributing to the structural diversity of self-assembled architectures.
COORDINATION CHEMISTRY REVIEWS
(2021)
Review
Chemistry, Inorganic & Nuclear
Matous Kloda, Sona Ondrusova, Kamil Lang, Jan Demel
Summary: This review summarizes the synthesis methods and functions of diaryl and dialkyl phosphinic acids as ligands in materials chemistry, highlighting their unique properties and diverse applications. Recent developments and future research directions in the field are also emphasized.
COORDINATION CHEMISTRY REVIEWS
(2021)
Article
Chemistry, Multidisciplinary
Sayan Kar, Jie Luo, Michael Rauch, Yael Diskin-Posner, Yehoshoa Ben-David, David Milstein
Summary: We report the dehydrogenative synthesis of esters from enol ethers using water as the formal oxidant, catalyzed by a newly developed ruthenium acridine-based PNP(Ph)-type complex. Mechanistic experiments and density functional theory (DFT) studies suggest that an inner-sphere stepwise coupled reaction pathway is operational instead of a more intuitive outer-sphere tandem hydration-dehydrogenation pathway.
Article
Chemistry, Physical
Satoshi Takebayashi, Mark A. Iron, Moran Feller, Orestes Rivada-Wheelaghan, Gregory Leitus, Yael Diskin-Posner, Linda J. W. Shimon, Liat Avram, Raanan Carmieli, Sharon G. Wolf, Ilit Cohen-Ofri, Rajashekharayya A. Sanguramath, Roy Shenhar, Moris Eisen, David Milstein
Summary: This study reports the discovery and mechanistic studies of three-coordinate iron(II) catalysts for ring-opening metathesis polymerization of olefins. The iron catalysts exhibited high reactivity and polymerization ability, suggesting their potential as economical and biocompatible catalysts for olefin metathesis reactions.
Article
Chemistry, Multidisciplinary
Jie Luo, Yaoyu Liang, Michael Montag, Yael Diskin-Posner, Liat Avram, David Milstein
Summary: This study introduces a novel strategy for the controllable semihydrogenation of internal alkynes using a catalytic thiol as a reversible inhibitor. Both (E)- and (Z)-alkenes can be selectively obtained under mild conditions using a single homogeneous acridine-based ruthenium pincer catalyst.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Article
Nanoscience & Nanotechnology
Ori Ezrah Mor, Tal Ohana, Adrien Borne, Yael Diskin-Posner, Maor Asher, Omer Yaffe, Abraham Shanzer, Barak Dayan
Summary: Crystals and fibers doped with rare-earth ions are essential for solid-state optical systems, but each has its own strengths and limitations. This study introduces a hybrid platform that coats a tapered silica optical fiber with a monolayer of complexes, providing high homogeneity and flexibility for different applications.
Article
Chemistry, Multidisciplinary
Yaoyu Liang, Uttam Kumar Das, Jie Luo, Yael Diskin-Posner, Liat Avram, David Milstein
Summary: This article presents a catalyst based on magnesium complexes and explores its potential in environmentally friendly organic transformations through metal-ligand cooperation for hydrogen activation. The catalyst showed remarkable performance in semihydrogenation of alkynes and hydrogenation of alkenes, providing high yields and selectivities.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Article
Chemistry, Physical
Guy Reuveni, Yael Diskin-Posner, Christian Gehrmann, Shravan Godse, Giannis G. Gkikas, Isaac Buchine, Sigalit Aharon, Roman Korobko, Constantinos C. Stoumpos, David A. Egger, Omer Yaffe
Summary: We demonstrate that formamidinium-based crystals differ from methyl ammonium-based halide perovskite crystals due to the presence of intrinsic local static disorder in their inorganic sublattice, despite having a well-defined average crystal structure. Our study combines terahertz-range Raman scattering, single-crystal X-ray diffraction, and first-principles calculations to investigate the temperature-dependent dynamics of the inorganic sublattice in the range of 10-300 K. The temperature evolution of the Raman spectra reveals that low-temperature, local static disorder significantly influences the crystal structural dynamics and phase transitions at higher temperatures.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2023)
Article
Chemistry, Multidisciplinary
Michael Montag, David Milstein
Summary: The amide functional group is widely distributed in living organisms and is particularly important in bioactive compounds and pharmaceuticals. However, the current method for amide synthesis relies heavily on traditional condensation reactions, which pose sustainability challenges. Therefore, developing sustainable approaches to amide synthesis is essential. Over the past two decades, homogeneous catalytic reactions, particularly ruthenium-catalyzed acceptorless dehydrogenative coupling, have been developed to achieve amide synthesis without coupling reagents and waste generation, with H-2 gas being the only byproduct.
PURE AND APPLIED CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Yaoyu Liang, Jie Luo, Yael Diskin-Posner, David Milstein
Summary: Utilization of main-group metals as alternatives to transition metals in homogeneous catalysis is a hot research area. However, their application in catalytic hydrogenation is less common due to the difficulty in heterolytic cleavage of the H-H bond. Employing metal-ligand cooperation highly enhances the H-2 activation process, offering an efficient approach for the hydrogenation of unsaturated molecules catalyzed by main-group metals.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Review
Chemistry, Multidisciplinary
Michael Montag, David Milstein
Summary: Pincer ligand complexes have been used for studying chemical processes and developing efficient catalysts for many chemical transformations. In this review, the authors discuss the development of phosphine-based pincer complexes containing main-group metals as alternatives to transition metals. Despite the mismatch between the soft Lewis bases of phosphines and hard Lewis acids of main-group metal ions, these complexes have shown to be active catalysts for industrially-relevant transformations.
ISRAEL JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Organic
Partha Jyoti Das, Ankana Roy, Ashim Nandi, Ishita Neogi, Yael Diskin-Posner, Vered Marks, Iddo Pinkas, Sara Amer, Sebastian Kozuch, Michael Firer, Michael Montag, Flavio Grynszpan
Summary: In this study, a series of thioxobimanes were synthesized and extensively characterized. The potential of these compounds as ligands for transition metals was demonstrated.
JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Kuntrapakam Hema, Angela B. Grommet, Michal J. Bialek, Jinhua Wang, Laura Schneider, Christoph Drechsler, Oksana Yanshyna, Yael Diskin-Posner, Guido H. Clever, Rafal Klajn
Summary: The architecture of self-assembled host molecules can significantly impact the properties of the encapsulated guests. A Pd6L4 coordination host has been found to exhibit a Janus nature, transforming from a tube-shaped isomer to a cage-shaped host upon encapsulating tetrahedrally shaped guests. The reversible toggling between these vastly different isomers allows for control over the functional properties of coordination hosts.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Chemistry, Multidisciplinary
Jie Luo, Lijun Lu, Michael Montag, Yaoyu Liang, David Milstein
Summary: The hydrogenative perdeuteration of alkenes, using readily available H2 and D2O, has been achieved in a single synthetic step with incorporation of up to 4.9 D atoms per C=C double bond. The reaction is catalysed by an acridanide-based ruthenium pincer complex, with the addition of a catalytic amount of thiol serving as a transient cooperative ligand. This method provides a route for installing perdeuteroalkyl groups at specific sites from widely available alkenes under mild conditions.
Article
Chemistry, Multidisciplinary
Yaoyu Liang, Jie Luo, Yael Diskin-Posner, David Milstein
Summary: The utilization of main-group metals in homogeneous catalysis as alternatives to transition metals has gained much attention recently. However, their application in catalytic hydrogenation is limited due to the difficulty in cleaving the H-H bond. In this study, new magnesium pincer complexes were developed and employed for the homogeneous catalytic hydrogenation of unsaturated molecules, showing promising results and expanding the scope of main-group metal catalysis.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Chemistry, Multidisciplinary
Elad Goren, Mark A. Iron, Yael Diskin-Posner, Alla Falkovich, Liat Avram, Amnon Bar-Shir
Summary: Metal-capped molecular hosts with paramagnetic properties can be used to study host-guest complexes and improve spectral resolution. The paraGEST method reveals different populations of complexes in a solution and allows for the identification of multiple co-existing populations of Ln-beta-CD-guest complexes.
Article
Chemistry, Multidisciplinary
Elad Goren, Mark A. Iron, Yael Diskin-Posner, Alla Falkovich, Liat Avram, Amnon Bar-Shir
Summary: Metal-capped molecular hosts with paramagnetic properties have been shown to be convenient for studying host-guest complexes in supramolecular systems using NMR spectroscopy. The paraGEST method, which utilizes paramagnetic guest exchange saturation transfer, allows for enhanced spectral resolution and the identification of different populations of host-guest complexes. This method is particularly useful for systems containing lanthanide-capped cyclodextrins, as it reveals multiple co-existing populations of complexes with different orientations of the guest molecules.
