Protectin DX ameliorates palmitate‐induced hepatic insulin resistance through AMPK / SIRT 1‐mediated modulation of fetuin‐A and SeP expression

Palmitate-induced IL6 expression ameliorated by chicoric acid through AMPK and SIRT1-mediated pathway in the PBMCs of newly diagnosed type 2 diabetes patients and healthy subjects

(2019) Zahra Arab Sadeghabadi et al.   CYTOKINE

Protectin DX attenuates LPS-induced inflammation and insulin resistance in adipocytes via AMPK-mediated suppression of the NFκB pathway

(2018) Tae Woo Jung et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Protectin DX Ameliorates Hepatic Steatosis by Suppression of Endoplasmic Reticulum Stress via AMPK-Induced ORP150 Expression

(2018) Tae Woo Jung et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Association between insulin resistance and the development of cardiovascular disease

(2018) Valeska Ormazabal et al.   Cardiovascular Diabetology

Activation of AMP-activated protein kinase rapidly suppresses multiple pro-inflammatory pathways in adipocytes including IL-1 receptor-associated kinase-4 phosphorylation

(2017) Sarah J. Mancini et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Deficiency of the hepatokine selenoprotein P increases responsiveness to exercise in mice through upregulation of reactive oxygen species and AMP-activated protein kinase in muscle

(2017) Hirofumi Misu et al.   NATURE MEDICINE

AMPK as a Therapeutic Target for Treating Metabolic Diseases

(2017) Emily A. Day et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Protectin DX ameliorates palmitate- or high-fat diet-induced insulin resistance and inflammation through an AMPK-PPARα-dependent pathway in mice

(2017) Tae Woo Jung et al.   Scientific Reports

Fibroblast growth factor 21 improves hepatic insulin sensitivity by inhibiting mammalian target of rapamycin complex 1 in mice

(2016) Qi Gong et al.   HEPATOLOGY

Free Fatty Acids Impair FGF21 Action in HepG2 Cells

(2015) Mohamed Asrih et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

The role of fatty acids in insulin resistance

(2015) Barry Sears et al.   Lipids in Health and Disease

Resveratrol prevents TNF-α-induced muscle atrophy via regulation of Akt/mTOR/FoxO1 signaling in C2C12 myotubes

(2014) Dong-Tao Wang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Effect of resveratrol on visceral white adipose tissue inflammation and insulin sensitivity in a mouse model of sleep apnea

(2014) A Carreras et al.   INTERNATIONAL JOURNAL OF OBESITY

Raison d'etre of insulin resistance: the adjustable threshold hypothesis

(2014) G. Wang   Journal of the Royal Society Interface

Exercise-Induced Lowering of Fetuin-A May Increase Hepatic Insulin Sensitivity

(2014) Steven K. Malin et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Protectin DX alleviates insulin resistance by activating a myokine-liver glucoregulatory axis

(2014) Phillip J White et al.   NATURE MEDICINE

Salsalate and adiponectin ameliorate hepatic steatosis by inhibition of the hepatokine fetuin-A

(2013) Tae Woo Jung et al.   BIOCHEMICAL PHARMACOLOGY

Antagonistic crosstalk between NF-κB and SIRT1 in the regulation of inflammation and metabolic disorders

(2013) Anu Kauppinen et al.   CELLULAR SIGNALLING

Role of AMP-activated protein kinase in adipose tissue metabolism and inflammation

(2013) Silvia Bijland et al.   CLINICAL SCIENCE

AMPK activator-mediated inhibition of endoplasmic reticulum stress ameliorates carrageenan-induced insulin resistance through the suppression of selenoprotein P in HepG2 hepatocytes

(2013) Tae Woo Jung et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Salsalate and Adiponectin Improve Palmitate-Induced Insulin Resistance via Inhibition of Selenoprotein P through the AMPK-FOXO1α Pathway

(2013) Tae Woo Jung et al.   PLoS One

Metformin Stimulates FGF21 Expression in Primary Hepatocytes

(2012) Eva B. Nygaard et al.   Experimental Diabetes Research

Effect of exercise on mouse liver and brain bioenergetic infrastructures

(2012) Lezi E. et al.   EXPERIMENTAL PHYSIOLOGY

Interleukin-6 mediates exercise-induced increase in insulin sensitivity in mice

(2012) Anna Benrick et al.   EXPERIMENTAL PHYSIOLOGY

Fetuin-A acts as an endogenous ligand of TLR4 to promote lipid-induced insulin resistance

(2012) Durba Pal et al.   NATURE MEDICINE

Sirtuins as regulators of metabolism and healthspan

(2012) Riekelt H. Houtkooper et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Globalization of Diabetes: The role of diet, lifestyle, and genes

(2011) F. B. Hu   DIABETES CARE

Fetuin A in nonalcoholic fatty liver disease: in vivo and in vitro studies

(2011) John Willy Haukeland et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Human HMGCS2 Regulates Mitochondrial Fatty Acid Oxidation andFGF21Expression in HepG2 Cell Line

(2011) Anna Vilà-Brau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AMP-activated protein kinase inhibits NF-κB signaling and inflammation: impact on healthspan and lifespan

(2011) Antero Salminen et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

NF-κB mediates lipid-induced fetuin-A expression in hepatocytes that impairs adipocyte function effecting insulin resistance

(2010) Suman Dasgupta et al.   BIOCHEMICAL JOURNAL

Comparing and contrasting the roles of AMPK and SIRT1 in metabolic tissues

(2010) Marcella Fulco et al.   CELL CYCLE

A Liver-Derived Secretory Protein, Selenoprotein P, Causes Insulin Resistance

(2010) Hirofumi Misu et al.   Cell Metabolism

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

(2009) Carles Cantó et al.   NATURE

Stimulation of selenoprotein P promoter activity in hepatoma cells by FoxO1a transcription factor

(2007) Philippe L. Walter et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Resveratrol sensitizes melanomas to TRAIL through modulation of antiapoptotic gene expression

(2007) Vladimir N. Ivanov et al.   EXPERIMENTAL CELL RESEARCH