“Turn‐On” Activatable AIE Dots for Tumor Hypoxia Imaging

Aggregation-Induced Emission (AIE) Dots: Emerging Theranostic Nanolights

(2018) Guangxue Feng et al.   ACCOUNTS OF CHEMICAL RESEARCH

Optical molecular imaging for tumor detection and image-guided surgery

(2018) Chensu Wang et al.   BIOMATERIALS

Azo Coupling Reaction Induced Macromolecular Self-Assembly in Aqueous Solution

(2018) Shang Li et al.   ACS Macro Letters

Hypoxia and cellular metabolism in tumour pathophysiology

(2017) Scott K. Parks et al.   JOURNAL OF PHYSIOLOGY-LONDON

NIR light and enzyme dual stimuli-responsive amphiphilic diblock copolymer assemblies

(2017) Jilei Wang et al.   JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

Development of an Azo-Based Photosensitizer Activated under Mild Hypoxia for Photodynamic Therapy

(2017) Wen Piao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hypoxia-Responsive Polymersomes for Drug Delivery to Hypoxic Pancreatic Cancer Cells

(2016) Prajakta Kulkarni et al.   BIOMACROMOLECULES

Fabrication of pH-Responsive Nanoparticles with an AIE Feature for Imaging Intracellular Drug Delivery

(2016) Xing Wang et al.   BIOMACROMOLECULES

Azoreductases in drug metabolism

(2016) Ali Ryan   BRITISH JOURNAL OF PHARMACOLOGY

Hypoxia-responsive nanocarriers for cancer imaging and therapy: recent approaches and future perspectives

(2016) Thavasyappan Thambi et al.   CHEMICAL COMMUNICATIONS

Imaging Agents in Targeting Tumor Hypoxia

(2016) Yun Zeng et al.   CURRENT MEDICINAL CHEMISTRY

A water-soluble conjugated polymer with azobenzol side chains based on “turn-on” effect for hypoxic cell imaging

(2016) Jie Li et al.   Polymer Chemistry

Organic Dots Based on AIEgens for Two-Photon Fluorescence Bioimaging

(2016) Xiaoding Lou et al.   Small

Induction of hypoxia and necrosis in multicellular tumor spheroids is associated with resistance to chemotherapy treatment

(2016) Silvio Däster et al.   Oncotarget

Photocleavable amphiphilic diblock copolymer with an azobenzene linkage

(2016) Jilei Wang et al.   RSC Advances

Fabrication of fluorescent nanoparticles based on AIE luminogens (AIE dots) and their applications in bioimaging

(2016) Sijie Chen et al.   Materials Horizons

NQO1 protein expression predicts poor prognosis of non-small cell lung cancers

(2015) Zhenling Li et al.   BMC CANCER

A turn-on fluorescent probe for tumor hypoxia imaging in living cells

(2015) Qi Cai et al.   CHEMICAL COMMUNICATIONS

Synthesis of side-on liquid crystalline diblock copolymers through macromolecular azo coupling reaction

(2015) Renbo Wei et al.   EUROPEAN POLYMER JOURNAL

Enzymatic ‘charging’ of synthetic polymers

(2015) Jingyi Rao et al.   Polymer Chemistry

3D cell culture systems modeling tumor growth determinants in cancer target discovery

(2014) Claudio R. Thoma et al.   ADVANCED DRUG DELIVERY REVIEWS

Aggregation-Induced Emission: The Whole Is More Brilliant than the Parts

(2014) Ju Mei et al.   ADVANCED MATERIALS

Hypoxia-Targeted siRNA Delivery

(2014) F. Perche et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Clinical implications of high NQO1 expression in breast cancers

(2014) Yang Yang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Activatable Cell Penetrating Peptide–Peptide Nucleic Acid Conjugate via Reduction of Azobenzene PEG Chains

(2014) Soo Hyeon Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enzyme-Triggered Cascade Reactions and Assembly of Abiotic Block Copolymers into Micellar Nanostructures

(2014) Jingyi Rao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tunable Heptamethine–Azo Dye Conjugate as an NIR Fluorescent Probe for the Selective Detection of Mitochondrial Glutathione over Cysteine and Homocysteine

(2014) Soo-Yeon Lim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Biocompatible and Photostable AIE Dots with Red Emission for In Vivo Two-Photon Bioimaging

(2014) Dan Wang et al.   Scientific Reports

Bioprobes Based on AIE Fluorogens

(2013) Dan Ding et al.   ACCOUNTS OF CHEMICAL RESEARCH

Development of Azo-Based Fluorescent Probes to Detect Different Levels of Hypoxia

(2013) Wen Piao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Diazobenzene-containing conjugated polymers as dark quenchers

(2013) Jiatao Wu et al.   CHEMICAL COMMUNICATIONS

Enzyme Sensitive Synthetic Polymer Micelles Based on the Azobenzene Motif

(2013) Jingyi Rao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Photostable fluorescent organic dots with aggregation-induced emission (AIE dots) for noninvasive long-term cell tracing

(2013) Kai Li et al.   Scientific Reports

The multicellular tumor spheroid model for high-throughput cancer drug discovery

(2012) Daniel V LaBarbera et al.   Expert Opinion on Drug Discovery

Synthesis of block copolymersvia the combination of RAFT and a macromolecular azo coupling reaction

(2012) Yaning He et al.   Polymer Chemistry

Synthesizing amphiphilic block copolymers through macromolecular azo-coupling reaction

(2011) Yaning He et al.   CHEMICAL COMMUNICATIONS

Hypoxia and Inflammation

(2011) Holger K. Eltzschig et al.   NEW ENGLAND JOURNAL OF MEDICINE

Hypoxia-Sensitive Fluorescent Probes forin VivoReal-Time Fluorescence Imaging of Acute Ischemia

(2010) Kazuki Kiyose et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Expansion of Substrate Specificity and Catalytic Mechanism of Azoreductase by X-ray Crystallography and Site-directed Mutagenesis

(2008) Kosuke Ito et al.   JOURNAL OF BIOLOGICAL CHEMISTRY