PACAP27 induces migraine-like attacks in migraine patients

Pharmacologic Characterization of ALD1910, a Potent Humanized Monoclonal Antibody against the Pituitary Adenylate Cyclase Activating Peptide

(2019) Cristina Moldovan Loomis et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

New insights about the peculiar role of the 28–38 C-terminal segment and some selected residues in PACAP for signaling and neuroprotection

(2018) Mathilde Poujol de Molliens et al.   BIOCHEMICAL PHARMACOLOGY

Headache Classification Committee of the International Headache Society (IHS) The International Classification of Headache Disorders, 3rd edition

(2018)   CEPHALALGIA

PACAP and its receptors in cranial arteries and mast cells

(2018) Inger Jansen-Olesen et al.   JOURNAL OF HEADACHE AND PAIN

Targeted Pituitary Adenylate Cyclase-Activating Peptide Therapies for Migraine

(2018) Anne Luise Haulund Vollesen et al.   Neurotherapeutics

Effect of the H1-antihistamine clemastine on PACAP38 induced migraine

(2018) Luise Haulund Vollesen et al.   CEPHALALGIA

Human models of migraine — short-term pain for long-term gain

(2017) Messoud Ashina et al.   Nature Reviews Neurology

PACAP38 dose-response pilot study in migraine patients

(2016) Anne Luise Haulund Vollesen et al.   CEPHALALGIA

Premonitory and nonheadache symptoms induced by CGRP and PACAP38 in patients with migraine

(2016) Song Guo et al.   PAIN

Localization of CGRP, CGRP receptor, PACAP and glutamate in trigeminal ganglion. Relation to the blood–brain barrier

(2015) Sajedeh Eftekhari et al.   BRAIN RESEARCH

Neuronal PAC 1 receptors mediate delayed activation and sensitization of trigeminocervical neurons: Relevance to migraine

(2015) Simon Akerman et al.   Science Translational Medicine

Phosphodiesterase 3 inhibitor cilostazol induces migraine-like attacks via cyclic AMP increase

(2014) Song Guo et al.   BRAIN

Investigation of the pathophysiological mechanisms of migraine attacks induced by pituitary adenylate cyclase-activating polypeptide-38

(2014) Faisal Mohammad Amin et al.   BRAIN

PACAP-38 infusion causes sustained vasodilation of the middle meningeal artery in the rat: Possible involvement of mast cells

(2014) Deepak K Bhatt et al.   CEPHALALGIA

PACAP-38 but not VIP induces release of CGRP from trigeminal nucleus caudalis via a receptor distinct from the PAC1 receptor

(2014) Inger Jansen-Olesen et al.   NEUROPEPTIDES

PACAP receptor pharmacology and agonist bias: analysis in primary neurons and glia from the trigeminal ganglia and transfected cells

(2013) C S Walker et al.   BRITISH JOURNAL OF PHARMACOLOGY

Dural mast cell degranulation is a putative mechanism for headache induced by PACAP-38

(2012) Michael Baun et al.   CEPHALALGIA

Peripheral and central alterations of pituitary adenylate cyclase activating polypeptide-like immunoreactivity in the rat in response to activation of the trigeminovascular system

(2012) Bernadett Tuka et al.   PEPTIDES

Headache and prolonged dilatation of the middle meningeal artery by PACAP38 in healthy volunteers

(2011) Faisal Mohammad Amin et al.   CEPHALALGIA

PACAP and a novel stable analog protect rat brain from ischemia: Insight into the mechanisms of action

(2011) Agnieszka Dejda et al.   PEPTIDES

Pharmacological characterization of VIP and PACAP receptors in the human meningeal and coronary artery

(2010) Kayi Y Chan et al.   CEPHALALGIA

The Importance of Engraftment in Flap Revascularization: Confirmation by Laser Speckle Perfusion Imaging

(2010) Paul G. McGuire et al.   JOURNAL OF SURGICAL RESEARCH

PACAP38 induces migraine-like attacks in patients with migraine without aura

(2008) Henrik Winther Schytz et al.   BRAIN

Vasoactive Intestinal Peptide Causes Marked Cephalic Vasodilation, but does not Induce Migraine

(2008) A Rahmann et al.   CEPHALALGIA

Novel stable PACAP analogs with potent activity towards the PAC1 receptor

(2008) Steve Bourgault et al.   PEPTIDES