PACAP receptor pharmacology and agonist bias: analysis in primary neurons and glia from the trigeminal ganglia and transfected cells

The Concise Guide to PHARMACOLOGY 2013/14: G Protein-Coupled Receptors

(2013) Stephen P.H. Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

Alterations in PACAP-38-like immunoreactivity in the plasma during ictal and interictal periods of migraine patients

(2013) Bernadett Tuka et al.   CEPHALALGIA

Role of VIP/PACAP in primary headaches

(2013) Lars Edvinsson   CEPHALALGIA

Magnetic resonance angiography of intracranial and extracranial arteries in patients with spontaneous migraine without aura: a cross-sectional study

(2013) Faisal Mohammad Amin et al.   LANCET NEUROLOGY

Signalling bias in new drug discovery: detection, quantification and therapeutic impact

(2013) Terry Kenakin et al.   NATURE REVIEWS DRUG DISCOVERY

CGRP and migraine: Could PACAP play a role too?

(2013) Eric A. Kaiser et al.   NEUROPEPTIDES

Novel designer receptors to probe GPCR signaling and physiology

(2013) Jürgen Wess et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Alternative Splicing of the Pituitary Adenylate Cyclase-Activating Polypeptide Receptor PAC1: Mechanisms of Fine Tuning of Brain Activity

(2013) Janna Blechman et al.   Frontiers in Endocrinology

Structure-Function of the G Protein–Coupled Receptor Superfamily

(2012) Vsevolod Katritch et al.   Annual Review of Pharmacology and Toxicology

Pharmacology and functions of receptors for vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide: IUPHAR Review 1

(2012) Anthony J Harmar et al.   BRITISH JOURNAL OF PHARMACOLOGY

Receptor activity-modifying protein-dependent impairment of calcitonin receptor splice variant Δ(1-47)hCT(a)function

(2012) T Qi et al.   BRITISH JOURNAL OF PHARMACOLOGY

Receptor activity modifying proteins (RAMPs) interact with the VPAC2receptor and CRF1receptors and modulate their function

(2012) D Wootten et al.   BRITISH JOURNAL OF PHARMACOLOGY

Dural mast cell degranulation is a putative mechanism for headache induced by PACAP-38

(2012) Michael Baun et al.   CEPHALALGIA

The 5-HT1F receptor agonist lasmiditan as a potential treatment of migraine attacks: a review of two placebo-controlled phase II trials

(2012) Peer C. Tfelt-Hansen et al.   JOURNAL OF HEADACHE AND PAIN

Functional Signaling Biases in G Protein-Coupled Receptors: Game Theory and Receptor Dynamics

(2012) S. Maudsley et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Consequences of splice variation on Secretin family G protein-coupled receptor function

(2011) Sebastian GB Furness et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Family B1 GPCR: Structural Aspects and Interaction with Accessory Proteins

(2011) Alain Couvineau et al.   CURRENT DRUG TARGETS

Neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP) slows down Alzheimer's disease-like pathology in amyloid precursor protein-transgenic mice

(2011) Dorothea Rat et al.   FASEB JOURNAL

Trends in the exploitation of novel drug targets

(2011) Mathias Rask-Andersen et al.   NATURE REVIEWS DRUG DISCOVERY

Pituitary adenylate cyclase-activating polypeptide plays a key role in nitroglycerol-induced trigeminovascular activation in mice

(2011) Adrienn Markovics et al.   NEUROBIOLOGY OF DISEASE

Inhibition of ERK phosphorylation by substance P N-terminal fragment decreases capsaicin-induced nociceptive response

(2011) Takaaki Komatsu et al.   NEUROPHARMACOLOGY

Crystal Structure of the PAC1R Extracellular Domain Unifies a Consensus Fold for Hormone Recognition by Class B G-Protein Coupled Receptors

(2011) Shiva Kumar et al.   PLoS One

Emerging migraine treatments and drug targets

(2011) Jes Olesen et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Guidelines for reporting experiments involving animals: the ARRIVE guidelines

(2010) JC McGrath et al.   BRITISH JOURNAL OF PHARMACOLOGY

Animal research: Reporting in vivo experiments: The ARRIVE guidelines

(2010) Carol Kilkenny et al.   BRITISH JOURNAL OF PHARMACOLOGY

Organ culture of the trigeminal ganglion induces enhanced expression of calcitonin gene-related peptide via activation of extracellular signal-regulated protein kinase 1/2

(2010) János Tajti et al.   CEPHALALGIA

The PACAP receptor: A novel target for migraine treatment

(2010) Henrik W. Schytz et al.   Neurotherapeutics

A key role for tryptophan 84 in receptor activity-modifying protein 1 in the amylin 1 receptor

(2010) Joseph J. Gingell et al.   PEPTIDES

The M3-muscarinic receptor regulates learning and memory in a receptor phosphorylation/arrestin-dependent manner

(2010) B. Poulin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fine-tuning of GPCR activity by receptor-interacting proteins

(2009) Stefanie L. Ritter et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Pituitary Adenylate Cyclase-Activating Polypeptide and Its Receptors: 20 Years after the Discovery

(2009) D. Vaudry et al.   PHARMACOLOGICAL REVIEWS

Calcitonin gene-related peptide stimulation of nitric oxide synthesis and release from trigeminal ganglion glial cells

(2008) Jing Li et al.   BRAIN RESEARCH

Vasoactive Intestinal Peptide Causes Marked Cephalic Vasodilation, but does not Induce Migraine

(2008) A Rahmann et al.   CEPHALALGIA

New Strategies in Drug Discovery for GPCRs: High Throughput Detection of Cellular ERK Phosphorylation

(2008) Michael Crouch et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

Animal models of migraine headache and aura

(2008) Katharina Eikermann-Haerter et al.   CURRENT OPINION IN NEUROLOGY

Receptor Activity-Modifying Proteins Differentially Modulate the G Protein-Coupling Efficiency of Amylin Receptors

(2008) Maria Morfis et al.   ENDOCRINOLOGY

β-Arrestin 1 Is Required for PAC1Receptor-mediated Potentiation of Long-lasting ERK1/2 Activation by Glucose in Pancreatic β-Cells

(2008) Christophe Broca et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Agonistic Behavior of PACAP6-38 on Sensory Nerve Terminals and Cytotrophoblast Cells

(2008) D Reglodi et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Central Pituitary Adenylate Cyclase 1 Receptors Modulate Nociceptive Behaviors in Both Inflammatory and Neuropathic Pain States

(2008) Rachel Davis-Taber et al.   JOURNAL OF PAIN