High-Mobility Group Box 1 Neutralization Prevents Chronic Cerebral Hypoperfusion-Induced Optic Tract Injuries in the White Matter Associated with Down-regulation of Inflammatory Responses

High mobility group box-1 (HMGB1) is increased in injured mouse spinal cord and can elicit neurotoxic inflammation

(2018) Kristina A. Kigerl et al.   BRAIN BEHAVIOR AND IMMUNITY

HMGB1 Neutralization Attenuates Hippocampal Neuronal Death and Cognitive Impairment in Rats with Chronic Cerebral Hypoperfusion via Suppressing Inflammatory Responses and Oxidative Stress

(2018) Yue Hei et al.   NEUROSCIENCE

Chronic cerebral hypoperfusion induces post-stroke dementia following acute ischemic stroke in rats

(2017) Dong Bin Back et al.   Journal of Neuroinflammation

High-mobility group box-1 as an autocrine trophic factor in white matter stroke

(2017) Jun Young Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Early Reperfusion After Brain Ischemia Has Beneficial Effects Beyond Rescuing Neurons

(2017) Masaki Tachibana et al.   STROKE

Anti-high mobility group box-1 (HMGB1) antibody inhibits hemorrhage-induced brain injury and improved neurological deficits in rats

(2017) Dengli Wang et al.   Scientific Reports

Cilostazol reduces blood brain barrier dysfunction, white matter lesion formation and motor deficits following chronic cerebral hypoperfusion

(2016) Hamidreza Edrissi et al.   BRAIN RESEARCH

HMGB1 induces apoptosis and EMT in association with increased autophagy following H/R injury in cardiomyocytes

(2016) FAN OUYANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

HMGB1 and thrombin mediate the blood-brain barrier dysfunction acting as biomarkers of neuroinflammation and progression to neurodegeneration in Alzheimer’s disease

(2016) Barry W. Festoff et al.   Journal of Neuroinflammation

Chronic cerebral hypoperfusion-induced impairment of Aβ clearance requires HB-EGF-dependent sequential activation of HIF1α and MMP9

(2016) Anushruti Ashok et al.   NEUROBIOLOGY OF DISEASE

Ginkgo biloba L. extract protects against chronic cerebral hypoperfusion by modulating neuroinflammation and the cholinergic system

(2016) Min-Soo Kim et al.   PHYTOMEDICINE

Systemic HMGB1 Neutralization Prevents Postoperative Neurocognitive Dysfunction in Aged Rats

(2016) Niccolò Terrando et al.   Frontiers in Immunology

Astroglial NF-kB contributes to white matter damage and cognitive impairment in a mouse model of vascular dementia

(2016) Raman Saggu et al.   Acta Neuropathologica Communications

Salvia miltiorrhiza extract protects white matter and the hippocampus from damage induced by chronic cerebral hypoperfusion in rats

(2015) Min-Soo Kim et al.   BMC Complementary and Alternative Medicine

Fructus mume alleviates chronic cerebral hypoperfusion-induced white matter and hippocampal damage via inhibition of inflammation and downregulation of TLR4 and p38 MAPK signaling

(2015) Ki Mo Lee et al.   BMC Complementary and Alternative Medicine

L-Carnitine Enhances Axonal Plasticity and Improves White-Matter Lesions after Chronic Hypoperfusion in Rat Brain

(2015) Yuji Ueno et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Systemic inflammation in early neonatal mice induces transient and lasting neurodegenerative effects

(2015) Filipa L Cardoso et al.   Journal of Neuroinflammation

Characterization of White Matter Injury in a Rat Model of Chronic Cerebral Hypoperfusion

(2015) Bo-Ryoung Choi et al.   STROKE

Astrocytes in Neurodegenerative Disease: Table 1.

(2015) Hemali Phatnani et al.   Cold Spring Harbor Perspectives in Biology

Long-Term Vision and Non-Vision Dominant Behavioral Deficits in the 2-VO Rats Are Accompanied by Time and Regional Glial Activation in the White Matter

(2014) Xue Song Tian et al.   PLoS One

The Translocation of Nuclear Molecules During Inflammation and Cell Death

(2013) David S. Pisetsky   ANTIOXIDANTS & REDOX SIGNALING

Vascular Risk Factors and Neurodegeneration in Ageing Related Dementias: Alzheimer’s Disease and Vascular Dementia

(2013) Rufus Akinyemi et al.   Current Alzheimer Research

Changes in Levels of Hypoxia-Induced Mediators in Rat Hippocampus During Chronic Cerebral Hypoperfusion

(2013) Ying Yang et al.   NEUROCHEMICAL RESEARCH

Biphasic Functional Regulation in Hippocampus of Rat with Chronic Cerebral Hypoperfusion Induced by Permanent Occlusion of Bilateral Common Carotid Artery

(2013) Jihye Bang et al.   PLoS One

The Ins and Outs of the BCCAo Model for Chronic Hypoperfusion: A Multimodal and Longitudinal MRI Approach

(2013) Guadalupe Soria et al.   PLoS One

High-mobility group box 1 from reactive astrocytes enhances the accumulation of endothelial progenitor cells in damaged white matter

(2012) Kazuhide Hayakawa et al.   JOURNAL OF NEUROCHEMISTRY

Gypenoside attenuates white matter lesions induced by chronic cerebral hypoperfusion in rats

(2011) Guanglin Zhang et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

White Matter Damage and Hippocampal Neurodegeneration Induced by Permanent Bilateral Occlusion of Common Carotid Artery in the Rat: Comparison between Wistar and Sprague-Dawley Strain

(2010) Seul-Ki Kim et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

Huperzine a improves chronic inflammation and cognitive decline in rats with cerebral hypoperfusion

(2009) Juan Wang et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Extracellular high mobility group box chromosomal protein 1 is a coupling factor for hypoxia and inflammation in arthritis

(2008) Takashi Hamada et al.   ARTHRITIS AND RHEUMATISM

High-Mobility Group Box-1 in Ischemia-Reperfusion Injury of the Heart

(2008) Martin Andrassy et al.   CIRCULATION

The plasticity of posterior communicating artery influences on the outcome of white matter injury induced by chronic cerebral hypoperfusion in rats

(2008) Seul-Ki Kim et al.   NEUROLOGICAL RESEARCH