MiR-124 reversed the doxorubicin resistance of breast cancer stem cells through STAT3/HIF-1 signaling pathways

Cancer stem cell in breast cancer therapeutic resistance

(2018) Xupeng Bai et al.   CANCER TREATMENT REVIEWS

Interaction between STAT3 and GLI1/tGLI1 oncogenic transcription factors promotes the aggressiveness of triple-negative breast cancers and HER2-enriched breast cancer

(2018) Sherona R. Sirkisoon et al.   ONCOGENE

let-7i-5p, miR-181a-2-3p and EGF/PI3K/SOX2 axis coordinate to maintain cancer stem cell population in cervical cancer

(2018) Ravindresh Chhabra   Scientific Reports

Tescalcin/c-Src/IGF1Rβ-mediated STAT3 activation enhances cancer stemness and radioresistant properties through ALDH1

(2018) Jei Ha Lee et al.   Scientific Reports

OCT4 Potentiates Radio-Resistance and Migration Activity of Rectal Cancer Cells by Improving Epithelial-Mesenchymal Transition in a ZEB1 Dependent Manner

(2018) Minghai Shao et al.   Biomed Research International

OCT4 directly regulates stemness and extracellular matrix-related genes in human germ cell tumours

(2018) Bomin Song et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Suppression of Breast Cancer Stem Cells and Tumor Growth by the RUNX1 Transcription Factor

(2018) Deli Hong et al.   MOLECULAR CANCER RESEARCH

miR-142-3p attenuates breast cancer stem cell characteristics and decreases radioresistance in vitro

(2018) Fabian M Troschel et al.   TUMOR BIOLOGY

Effects of miRNAs on functions of breast cancer stem cells and treatment of breast cancer

(2018) Ying Zhang et al.   OncoTargets and Therapy

APC loss in breast cancer leads to doxorubicin resistance via STAT3 activation

(2017) Monica K. VanKlompenberg et al.   Oncotarget

MicroRNA-124 enhances response to radiotherapy in human epidermal growth factor receptor 2-positive breast cancer cells by targeting signal transducer and activator of transcription 3

(2016) Ying Fu et al.   CROATIAN MEDICAL JOURNAL

RETRACTED ARTICLE: miR-124 Acts as a Tumor Suppressor in Glioblastoma via the Inhibition of Signal Transducer and Activator of Transcription 3

(2016) Weihao Li et al.   MOLECULAR NEUROBIOLOGY

Epithelial-mesenchymal transition in tumor metastasis

(2016) Kay T. Yeung et al.   Molecular Oncology

MicroRNA-124 inhibits cell proliferation and migration by regulating SNAI2 in breast cancer

(2016) Shanmei Du et al.   ONCOLOGY REPORTS

miR-124 downregulation leads to breast cancer progression via LncRNA-MALAT1 regulation and CDK4/E2F1 signal activation

(2016) Tongbao Feng et al.   Oncotarget

Sulforaphane improves chemotherapy efficacy by targeting cancer stem cell-like properties via the miR-124/IL-6R/STAT3 axis

(2016) Xingxing Wang et al.   Scientific Reports

Breast cancer

(2015) Chris Woolston   NATURE

Estrogen receptor-α directly regulates the hypoxia-inducible factor 1 pathway associated with antiestrogen response in breast cancer

(2015) Jun Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct prognostic values of ALDH1 isoenzymes in breast cancer

(2015) Shaokun Wu et al.   TUMOR BIOLOGY

Enhanced SLC34A2 in breast cancer stem cell-like cells induces chemotherapeutic resistance to doxorubicin via SLC34A2-Bmi1-ABCC5 signaling

(2015) Guanqun Ge et al.   TUMOR BIOLOGY

Establishment and characterization of a bladder cancer cell line with enhanced doxorubicin resistance by mevalonate pathway activation

(2015) Annemarie Greife et al.   TUMOR BIOLOGY

Hypoxia-inducible factors are required for chemotherapy resistance of breast cancer stem cells

(2014) Debangshu Samanta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-124 inhibits cellular proliferation and invasion by targeting Ets-1 in breast cancer

(2014) Wentao Li et al.   TUMOR BIOLOGY

MicroRNA-124 mediates the cholinergic anti-inflammatory action through inhibiting the production of pro-inflammatory cytokines

(2013) Yang Sun et al.   CELL RESEARCH

Microrna-124 targets flotillin-1 to regulate proliferation and migration in breast cancer

(2013) Laisheng Li et al.   Molecular Cancer

STAT3 and HIF1α cooperatively activate HIF1 target genes in MDA-MB-231 and RCC4 cells

(2013) M R Pawlus et al.   ONCOGENE

HIF-1α downregulates miR-17/20a directly targeting p21 and STAT3: a role in myeloid leukemic cell differentiation

(2012) M He et al.   CELL DEATH AND DIFFERENTIATION

Gene expression alterations in doxorubicin resistant MCF7 breast cancer cell line

(2012) Shatha AbuHammad et al.   GENOMICS

Nanocarriers Enhance Doxorubicin Uptake in Drug-Resistant Ovarian Cancer Cells

(2011) H. C. Arora et al.   CANCER RESEARCH

Prolonged Drug Selection of Breast Cancer Cells and Enrichment of Cancer Stem Cell Characteristics

(2010) Anna Maria Calcagno et al.   JNCI-Journal of the National Cancer Institute