Tumor-secreted PAI-1 promotes breast cancer metastasis via the induction of adipocyte-derived collagen remodeling
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Tumor-secreted PAI-1 promotes breast cancer metastasis via the induction of adipocyte-derived collagen remodeling
Authors
Keywords
Breast Cancer, PAI-1, PLOD2, Microenvironment, Metastasis, Collagen
Journal
Cell Communication and Signaling
Volume 17, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-06-06
DOI
10.1186/s12964-019-0373-z
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- A feedback loop between hypoxia and matrix stress relaxation increases oxygen-axis migration and metastasis in sarcoma
- (2019) Daniel M Lewis et al. CANCER RESEARCH
- Exosomes secreted by mesenchymal stromal/stem cell-derived adipocytes promote breast cancer cell growth via activation of Hippo signaling pathway
- (2019) Shihua Wang et al. Stem Cell Research & Therapy
- Dual prognostic role of 2-oxoglutarate-dependent oxygenases in ten cancer types: implications for cell cycle regulation and cell adhesion maintenance
- (2019) Wai Hoong Chang et al. Cancer Communications
- Plasminogen activator inhibitor-1 in cancer research
- (2018) Sijing Li et al. BIOMEDICINE & PHARMACOTHERAPY
- PAI-1 induces Src inhibitor resistance via CCL5 in HER2-positive breast cancer cells
- (2018) Hehui Fang et al. CANCER SCIENCE
- Pentachloropseudilin Inhibits Transforming Growth Factor-β (TGF-β) Activity by Accelerating Cell-Surface Type II TGF-β Receptor Turnover in Target Cells
- (2018) Chih-Ling Chung et al. CHEMBIOCHEM
- Endothelial cells promote triple-negative breast cancer cell metastasis via PAI-1 and CCL5 signaling
- (2018) Wenwen Zhang et al. FASEB JOURNAL
- PLOD2 as a potential regulator of peritoneal dissemination in gastric cancer
- (2018) Yuki Kiyozumi et al. INTERNATIONAL JOURNAL OF CANCER
- Hypoxia-Induced PLOD2 is a Key Regulator in Epithelial-Mesenchymal Transition and Chemoresistance in Biliary Tract Cancer
- (2018) Yuichiro Okumura et al. ANNALS OF SURGICAL ONCOLOGY
- Adipocyte-derived IL-6 and leptin promote breast Cancer metastasis via upregulation of Lysyl Hydroxylase-2 expression
- (2018) Jin-Yong He et al. Cell Communication and Signaling
- PAI-1 secreted from metastatic ovarian cancer cells triggers the tumor-promoting role of the mesothelium in a feedback loop to accelerate peritoneal dissemination
- (2018) Yang Peng et al. CANCER LETTERS
- FOXP1 controls mesenchymal stem cell commitment and senescence during skeletal aging
- (2017) Hanjun Li et al. JOURNAL OF CLINICAL INVESTIGATION
- Adipocyte–Tumor Cell Metabolic Crosstalk in Breast Cancer
- (2017) Andrew J. Hoy et al. TRENDS IN MOLECULAR MEDICINE
- PLOD2 regulated by transcription factor FOXA1 promotes metastasis in NSCLC
- (2017) Hongzhi Du et al. Cell Death & Disease
- Adipocytes promote malignant growth of breast tumours with monocarboxylate transporter 2 expression via β-hydroxybutyrate
- (2017) Chun-Kai Huang et al. Nature Communications
- FOXP1 Promotes Embryonic Neural Stem Cell Differentiation by Repressing Jagged1 Expression
- (2017) Luca Braccioli et al. Stem Cell Reports
- Tumour-suppressive miRNA-26a-5p and miR-26b-5p inhibit cell aggressiveness by regulating PLOD2 in bladder cancer
- (2016) K Miyamoto et al. BRITISH JOURNAL OF CANCER
- Hypoxic stellate cells of pancreatic cancer stroma regulate extracellular matrix fiber organization and cancer cell motility
- (2016) Masafumi Sada et al. CANCER LETTERS
- Interactions between Adipocytes and Breast Cancer Cells Stimulate Cytokine Production and Drive Src/Sox2/miR-302b–Mediated Malignant Progression
- (2016) Manuel Picon-Ruiz et al. CANCER RESEARCH
- Molecular insights into prolyl and lysyl hydroxylation of fibrillar collagens in health and disease
- (2016) Rutger A. F. Gjaltema et al. CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Confocal fluorescence microscopy to evaluate changes in adipocytes in the tumor microenvironment associated with invasive ductal carcinoma and ductal carcinomain situ
- (2016) Jessica L. Dobbs et al. INTERNATIONAL JOURNAL OF CANCER
- Regulation of the collagen cross-linking enzymes LOXL2 and PLOD2 by tumor-suppressive microRNA-26a/b in renal cell carcinoma
- (2016) AKIRA KUROZUMI et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Oriented collagen fibers direct tumor cell intravasation
- (2016) Weijing Han et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PAI-1, a target gene of miR-143, regulates invasion and metastasis by upregulating MMP-13 expression of human osteosarcoma
- (2016) Mio Hirahata et al. Cancer Medicine
- Cancer-mediated adipose reversion promotes cancer cell migration via IL-6 and MCP-1
- (2015) Kaoru Fujisaki et al. BREAST CANCER RESEARCH AND TREATMENT
- Plasminogen Activator Inhibitor-1 in Cancer: Rationale and Insight for Future Therapeutic Testing
- (2015) V. R. Placencio et al. CANCER RESEARCH
- Lysyl hydroxylase 2 induces a collagen cross-link switch in tumor stroma
- (2015) Yulong Chen et al. JOURNAL OF CLINICAL INVESTIGATION
- FOXP1 suppresses immune response signatures and MHC class II expression in activated B-cell-like diffuse large B-cell lymphomas
- (2015) P J Brown et al. LEUKEMIA
- Cancer-Associated Fibroblasts Induce a Collagen Cross-link Switch in Tumor Stroma
- (2015) D. Pankova et al. MOLECULAR CANCER RESEARCH
- Silencing of plasminogen activator inhibitor-1 suppresses colorectal cancer progression and liver metastasis
- (2015) Han Chen et al. SURGERY
- Plasminogen Activator Inhibitor 1 Protects Fibrosarcoma Cells from Etoposide-Induced Apoptosis through Activation of the PI3K/Akt Cell Survival Pathway
- (2015) Maria U. Rømer et al. NEOPLASIA
- Cancer-Associated Adipose Tissue Promotes Breast Cancer Progression by Paracrine Oncostatin M and Jak/STAT3 Signaling
- (2014) L. Lapeire et al. CANCER RESEARCH
- Lysine post-translational modifications of collagen
- (2014) Mitsuo Yamauchi et al. Essays in Biochemistry
- Interleukin-6 (IL-6) Trans Signaling Drives a STAT3-dependent Pathway That Leads to Hyperactive Transforming Growth Factor-β (TGF-β) Signaling Promoting SMAD3 Activation and Fibrosis via Gremlin Protein
- (2014) Steven O'Reilly et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Adipocyte-Derived Fibroblasts Promote Tumor Progression and Contribute to the Desmoplastic Reaction in Breast Cancer
- (2013) L. Bochet et al. CANCER RESEARCH
- Hypoxia-inducible Factor 1 (HIF-1) Promotes Extracellular Matrix Remodeling under Hypoxic Conditions by InducingP4HA1, P4HA2,andPLOD2Expression in Fibroblasts
- (2013) Daniele M. Gilkes et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Targeting Plasminogen Activator Inhibitor-1 Inhibits Angiogenesis and Tumor Growth in a Human Cancer Xenograft Model
- (2013) E. Gomes-Giacoia et al. MOLECULAR CANCER THERAPEUTICS
- Mature breast adipocytes promote breast cancer cell motility
- (2012) Jennifer C. Carter et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- Adipocyte-derived endotrophin promotes malignant tumor progression
- (2012) Jiyoung Park et al. JOURNAL OF CLINICAL INVESTIGATION
- Plasminogen activator inhibitor type 1 regulates microglial motility and phagocytic activity
- (2012) Hyejin Jeon et al. Journal of Neuroinflammation
- Aligned Collagen Is a Prognostic Signature for Survival in Human Breast Carcinoma
- (2011) Matthew W. Conklin et al. AMERICAN JOURNAL OF PATHOLOGY
- Cancer-Associated Adipocytes Exhibit an Activated Phenotype and Contribute to Breast Cancer Invasion
- (2011) B. Dirat et al. CANCER RESEARCH
- On the Role of FOX Transcription Factors in Adipocyte Differentiation and Insulin-stimulated Glucose Uptake
- (2009) Isabelle Gerin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Stroma in breast development and disease
- (2009) Lisa M. Arendt et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More