Extracellular ATP promotes breast cancer invasion and epithelial‐mesenchymal transition via hypoxia‐inducible factor 2α signaling

Krüppel-like factor 9 down-regulates matrix metalloproteinase 9 transcription and suppresses human breast cancer invasion

(2018) Xiao-Yan Bai et al.   CANCER LETTERS

Extracellular ATP drives breast cancer cell migration and metastasis via S100A4 production by cancer cells and fibroblasts

(2018) Ying Liu et al.   CANCER LETTERS

HIF2α in the uterine stroma permits embryo invasion and luminal epithelium detachment

(2018) Leona Matsumoto et al.   JOURNAL OF CLINICAL INVESTIGATION

LOX-catalyzed collagen stabilization is a proximal cause for intrinsic resistance to chemotherapy

(2018) Leonie Rossow et al.   ONCOGENE

Biphasic Effect of ATP on In Vitro Mineralization of Dental Pulp Cells

(2017) Oranuch Techatharatip et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Use of luciferase probes to measure ATP in living cells and animals

(2017) Giampaolo Morciano et al.   Nature Protocols

The transcription factor EPAS1 links DOCK8 deficiency to atopic skin inflammation via IL-31 induction

(2017) Kazuhiko Yamamura et al.   Nature Communications

FOXK2 Elicits Massive Transcription Repression and Suppresses the Hypoxic Response and Breast Cancer Carcinogenesis

(2016) Lin Shan et al.   CANCER CELL

EMT: 2016

(2016) M. Angela Nieto et al.   CELL

Mitochondria-Translocated PGK1 Functions as a Protein Kinase to Coordinate Glycolysis and the TCA Cycle in Tumorigenesis

(2016) Xinjian Li et al.   MOLECULAR CELL

On-target efficacy of a HIF-2α antagonist in preclinical kidney cancer models

(2016) Hyejin Cho et al.   NATURE

Extracellular purines, purinergic receptors and tumor growth

(2016) F Di Virgilio et al.   ONCOGENE

Sterile Inflammation Enhances ECM Degradation in Integrin β1 KO Embryonic Skin

(2016) Ambika S. Kurbet et al.   Cell Reports

ATP-Citrate Lyase Controls a Glucose-to-Acetate Metabolic Switch

(2016) Steven Zhao et al.   Cell Reports

Hypoxia induced epithelial–mesenchymal transition and vasculogenic mimicry formation by promoting Bcl-2/Twist1 cooperation

(2015) Kun Liu et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Structural integration in hypoxia-inducible factors

(2015) Dalei Wu et al.   NATURE

Correction: Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1

(2015) Shiwen Wang et al.   PLOS BIOLOGY

P2Y2 Receptor and EGFR Cooperate to Promote Prostate Cancer Cell Invasion via ERK1/2 Pathway

(2015) Wei-Hua Li et al.   PLoS One

A Long Noncoding RNA Activated by TGF-β Promotes the Invasion-Metastasis Cascade in Hepatocellular Carcinoma

(2014) Ji-hang Yuan et al.   CANCER CELL

P2X7 Mediates ATP-Driven Invasiveness in Prostate Cancer Cells

(2014) Ying Qiu et al.   PLoS One

P2Y2 receptor promotes cell invasion and metastasis in prostate cancer cells

(2013) W-H Li et al.   BRITISH JOURNAL OF CANCER

Purinergic signalling and cancer

(2013) Geoffrey Burnstock et al.   Purinergic Signalling

Hypoxia-Inducible Factors: Mediators of Cancer Progression; Prognostic and Therapeutic Targets in Soft Tissue Sarcomas

(2013) Navid Sadri et al.   Cancers

Intracellular ATP levels determine cell death fate of cancer cells exposed to both standard and redox chemotherapeutic agents

(2011) Julien Verrax et al.   BIOCHEMICAL PHARMACOLOGY

The Hypoxia-Associated Factor Switches Cells from HIF-1 - to HIF-2 -Dependent Signaling Promoting Stem Cell Characteristics, Aggressive Tumor Growth and Invasion

(2011) M. Y. Koh et al.   CANCER RESEARCH

Overexpression of MMP-9 and HIF-1α in Breast Cancer Cells under Hypoxic Conditions

(2011) Jae Young Choi et al.   Journal of Breast Cancer

Understanding the role of SOX9 in acquired diseases: lessons from development

(2011) James Pritchett et al.   TRENDS IN MOLECULAR MEDICINE

The Lysyl Oxidases LOX and LOXL2 Are Necessary and Sufficient to Repress E-cadherin in Hypoxia

(2009) Ruth Schietke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human cancers converge at the HIF-2α oncogenic axis

(2009) Aleksandra Franovic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct regulation of TWIST by HIF-1α promotes metastasis

(2008) Muh-Hwa Yang et al.   NATURE CELL BIOLOGY

Increased Level of Extracellular ATP at Tumor Sites: In Vivo Imaging with Plasma Membrane Luciferase

(2008) Patrizia Pellegatti et al.   PLoS One

Digoxin and other cardiac glycosides inhibit HIF-1  synthesis and block tumor growth

(2008) H. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA