Celastrol enhances TRAIL-induced apoptosis in human glioblastoma via the death receptor pathway

Glioblastoma and chemoresistance to alkylating agents: Involvement of apoptosis, autophagy, and unfolded protein response

(2018) Sabine Hombach-Klonisch et al.   PHARMACOLOGY & THERAPEUTICS

A Mechanistic Overview of Triptolide and Celastrol, Natural Products from Tripterygium wilfordii Hook F

(2018) Shao-Ru Chen et al.   Frontiers in Pharmacology

A new mechanism of inhibition of IL-1β secretion by celastrol through the NLRP3 inflammasome pathway

(2017) Wenyu Xin et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

DATS sensitizes glioma cells to TRAIL-mediated apoptosis by up-regulation of death receptor 5 via ROS

(2017) Jung Soon Hwang et al.   FOOD AND CHEMICAL TOXICOLOGY

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

(2016) David N. Louis et al.   ACTA NEUROPATHOLOGICA

Intracellular localization of DR5 and related regulatory pathways as a mechanism of resistance to TRAIL in cancer

(2016) Ufuk Mert et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Celastrol ameliorates experimental colitis in IL-10 deficient mice via the up-regulation of autophagy

(2015) Jie Zhao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Celastrol induces apoptosis and autophagy via the ROS/JNK signaling pathway in human osteosarcoma cells: an in vitro and in vivo study

(2015) H-Y Li et al.   Cell Death & Disease

Evodiamine sensitizes U87 glioblastoma cells to TRAIL via the death receptor pathway

(2014) MUHAMMAD KHAN et al.   Molecular Medicine Reports

Celastrol targets proteostasis and acts synergistically with a heat-shock protein 90 inhibitor to kill human glioblastoma cells

(2014) S Boridy et al.   Cell Death & Disease

Celastrol inhibits growth and induces apoptotic cell death in melanoma cells via the activation ROS-dependent mitochondrial pathway and the suppression of PI3K/AKT signaling

(2012) Ju-Hye Lee et al.   APOPTOSIS

Up-regulation of death receptor 4 and 5 by celastrol enhances the anti-cancer activity of TRAIL/Apo-2L

(2010) Hong Zhu et al.   CANCER LETTERS

Naringenin up-regulates the expression of death receptor 5 and enhances TRAIL-induced apoptosis in human lung cancer A549 cells

(2010) Cheng-Yun Jin et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Synergistic Anti-Cancer Activity by the Combination of TRAIL/APO-2L and Celastrol

(2009) Hong Zhu et al.   CANCER INVESTIGATION

Two hour exposure to sodium butyrate sensitizes bladder cancer to anticancer drugs

(2008) Degui Wang et al.   INTERNATIONAL JOURNAL OF UROLOGY

Quercetin promotes degradation of survivin and thereby enhances death-receptor–mediated apoptosis in glioma cells

(2008) Markus D. Siegelin et al.   NEURO-ONCOLOGY