miR-125b-5p inhibits cell proliferation, migration, and invasion in hepatocellular carcinoma via targeting TXNRD1

Age independent survival benefit for patients with hepatocellular carcinoma (HCC) without metastases at diagnosis: a population-based study

(2019) Enrico N De Toni et al.   GUT

Cancer-cell-secreted exosomal miR-105 promotes tumour growth through the MYC-dependent metabolic reprogramming of stromal cells

(2018) Wei Yan et al.   NATURE CELL BIOLOGY

Irreversible inhibition of cytosolic thioredoxin reductase 1 as a mechanistic basis for anticancer therapy

(2018) William C. Stafford et al.   Science Translational Medicine

The thioredoxin-1 system is essential for fueling DNA synthesis during T-cell metabolic reprogramming and proliferation

(2018) Jonathan Muri et al.   Nature Communications

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Clinical Significance of the Thioredoxin System and Thioredoxin-Domain-Containing Protein Family in Hepatocellular Carcinoma

(2018) Sang Yeon Cho et al.   DIGESTIVE DISEASES AND SCIENCES

Induction of Oxidative Stress via Inhibition of Thioredoxin Reductase 1 is an Effective Therapeutic Approach for Hepatocellular Carcinoma

(2018) Derek Lee et al.   HEPATOLOGY

The role of exosomes and miRNAs in drug-resistance of cancer cells

(2017) Duc-Hiep Bach et al.   INTERNATIONAL JOURNAL OF CANCER

miR-25/93 mediates hypoxia-induced immunosuppression by repressing cGAS

(2017) Min-Zu Wu et al.   NATURE CELL BIOLOGY

MicroRNA therapeutics: towards a new era for the management of cancer and other diseases

(2017) Rajesha Rupaimoole et al.   NATURE REVIEWS DRUG DISCOVERY

miR-125b-5p enhances chemotherapy sensitivity to cisplatin by down-regulating Bcl2 in gallbladder cancer

(2017) Dong Yang et al.   Scientific Reports

miR-500a-5p regulates oxidative stress response genes in breast cancer and predicts cancer survival

(2017) Davide Degli Esposti et al.   Scientific Reports

Piperlongumine as a direct TrxR1 inhibitor with suppressive activity against gastric cancer

(2016) Peng Zou et al.   CANCER LETTERS

TrxR1 inhibition overcomes both hypoxia-induced and acquired bortezomib resistance in multiple myeloma through NF-кβ inhibition

(2016) Prahlad V. Raninga et al.   CELL CYCLE

Role of apoptosis-related miRNAs in resveratrol-induced breast cancer cell death

(2016) R Venkatadri et al.   Cell Death & Disease

TUSC2(FUS1)-erlotinib Induced Vulnerabilities in Epidermal Growth Factor Receptor(EGFR) Wildtype Non-small Cell Lung Cancer(NSCLC) Targeted by the Repurposed Drug Auranofin

(2016) Cao Xiaobo et al.   Scientific Reports

Thioredoxin reductase 1 suppresses adipocyte differentiation and insulin responsiveness

(2016) Xiaoxiao Peng et al.   Scientific Reports

MicroRNA-125b attenuates epithelial-mesenchymal transitions and targets stem-like liver cancer cells through small mothers against decapentaplegic 2 and 4

(2015) Jun-Nian Zhou et al.   HEPATOLOGY

Selective targeting of IRF4 by synthetic microRNA-125b-5p mimics induces anti-multiple myeloma activity in vitro and in vivo

(2015) E Morelli et al.   LEUKEMIA

Methionine sulfoxide reductase: Chemistry, substrate binding, recycling process and oxidase activity

(2014) Sandrine Boschi-Muller et al.   BIOORGANIC CHEMISTRY

miR-125bcan enhance skin tumor initiation and promote malignant progression by repressing differentiation and prolonging cell survival

(2014) Liang Zhang et al.   GENES & DEVELOPMENT

Histone lysine methyltransferase, suppressor of variegation 3-9 homolog 1, promotes hepatocellular carcinoma progression and is negatively regulated by microRNA-125b

(2012) Dorothy Ngo-Yin Fan et al.   HEPATOLOGY

Sirtuin7 oncogenic potential in human hepatocellular carcinoma and its regulation by the tumor suppressors MiR-125a-5p and MiR-125b

(2012) Jeong Kyu Kim et al.   HEPATOLOGY

Regulation of placenta growth factor by microRNA-125b in hepatocellular cancer

(2011) Gianfranco Alpini et al.   JOURNAL OF HEPATOLOGY

MicroRNA-125b suppressesed human liver cancer cell proliferation and metastasis by directly targeting oncogene LIN28B2

(2010) Linhui Liang et al.   HEPATOLOGY

Focus on mammalian thioredoxin reductases — Important selenoproteins with versatile functions

(2009) Elias S.J. Arnér   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS