A germline mutation in Rab43 gene identified from a cancer family predisposes to a hereditary liver-colon cancer syndrome

Large-scale meta-analysis of mutations identified in panels of breast/ovarian cancer-related genes — Providing evidence of cancer predisposition genes

(2019) Malwina Suszynska et al.   GYNECOLOGIC ONCOLOGY

Piwi-like 1 and -2 protein expression levels are prognostic factors for muscle invasive urothelial bladder cancer patients

(2018) Markus Eckstein et al.   Scientific Reports

High expression of RAB43 predicts poor prognosis and is associated with epithelial-mesenchymal transition in gliomas

(2017) Ming-Zhi Han et al.   ONCOLOGY REPORTS

The GTPase Rab43 Controls the Anterograde ER-Golgi Trafficking and Sorting of GPCRs

(2017) Chunman Li et al.   Cell Reports

InheritedTP53Mutations and the Li–Fraumeni Syndrome

(2017) Tanya Guha et al.   Cold Spring Harbor Perspectives in Medicine

Prevalence and Spectrum of Germline Cancer Susceptibility Gene Mutations Among Patients With Early-Onset Colorectal Cancer

(2017) Rachel Pearlman et al.   JAMA Oncology

Rab43 regulates the sorting of a subset of membrane protein cargo through the medial Golgi

(2016) John V. Cox et al.   MOLECULAR BIOLOGY OF THE CELL

Preadipocyte factor 1 induces pancreatic ductal cell differentiation into insulin-producing cells

(2016) Marie Rhee et al.   Scientific Reports

shRNA library screening identifies nucleocytoplasmic transport as a mediator of BCR-ABL1 kinase-independent resistance

(2015) J. S. Khorashad et al.   BLOOD

Comprehensive spectrum ofBRCA1andBRCA2deleterious mutations in breast cancer in Asian countries

(2015) Ava Kwong et al.   JOURNAL OF MEDICAL GENETICS

Biochemical and Structural Analysis of Common Cancer-Associated KRAS Mutations

(2015) J. C. Hunter et al.   MOLECULAR CANCER RESEARCH

Exome sequencing of a colorectal cancer family reveals shared mutation pattern and predisposition circuitry along tumor pathways

(2015) Suleiman H. Suleiman et al.   Frontiers in Genetics

An ShRNA Based Genetic Screen Identified Sesn2 as a Potential Tumor Suppressor in Lung Cancer via Suppression of Akt-mTOR-p70S6K Signaling

(2015) Hui Xu et al.   PLoS One

Exome sequencing identifies a novel mutation in PIK3R1 as the cause of SHORT syndrome

(2014) Clea Bárcena et al.   BMC Medical Genetics

New genes emerging for colorectal cancer predisposition

(2014) Clara Esteban-Jurado   WORLD JOURNAL OF GASTROENTEROLOGY

Identification of Novel Variants in Colorectal Cancer Families by High-Throughput Exome Sequencing

(2013) M. S. DeRycke et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

The GTPase-Activating Protein RN-tre Controls Focal Adhesion Turnover and Cell Migration

(2013) Andrea Palamidessi et al.   CURRENT BIOLOGY

Exome Resequencing Identifies Potential Tumor-Suppressor Genes that Predispose to Colorectal Cancer

(2013) Christopher G. Smith et al.   HUMAN MUTATION

Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells

(2013) Ophir Shalem et al.   SCIENCE

Genetic Screens in Human Cells Using the CRISPR-Cas9 System

(2013) Tim Wang et al.   SCIENCE

Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas

(2012) Claire Palles et al.   NATURE GENETICS

Hereditary and Familial Colon Cancer

(2010) Kory W. Jasperson et al.   GASTROENTEROLOGY

Genome-wide linkage scan for colorectal cancer susceptibility genes supports linkage to chromosome 3q

(2008) Simone Picelli et al.   BMC CANCER

Rab18 and Rab43 have key roles in ER-Golgi trafficking

(2008) S. Y. Dejgaard et al.   JOURNAL OF CELL SCIENCE

The complete genome of an individual by massively parallel DNA sequencing

(2008) David A. Wheeler et al.   NATURE

Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer

(2008)   NATURE GENETICS

Heritable somatic methylation and inactivation of MSH2 in families with Lynch syndrome due to deletion of the 3′ exons of TACSTD1

(2008) Marjolijn J L Ligtenberg et al.   NATURE GENETICS