Hypoxia Triggers Osteochondrogenic Differentiation of Vascular Smooth Muscle Cells in an HIF-1 (Hypoxia-Inducible Factor 1)–Dependent and Reactive Oxygen Species–Dependent Manner

Coronary Artery Calcification

(2017) Takehiro Nakahara et al.   JACC-Cardiovascular Imaging

Mitochondrial composition and function under the control of hypoxia

(2017) Dominik C. Fuhrmann et al.   Redox Biology

Redox signaling during hypoxia in mammalian cells

(2017) Kimberly A. Smith et al.   Redox Biology

Role for Runt-related Transcription Factor 2 in Proliferative and Calcified Vascular Lesions in Pulmonary Arterial Hypertension

(2016) Grégoire Ruffenach et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A novel organ culture model of aorta for vascular calcification

(2016) Takuyu Akiyoshi et al.   ATHEROSCLEROSIS

Osteogenic differentiation of human lens epithelial cells might contribute to lens calcification

(2016) Enikő Balogh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Iron overload inhibits osteogenic commitment and differentiation of mesenchymal stem cells via the induction of ferritin

(2016) Enikő Balogh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Hypoxia-inducible factor-1 plays a role in phosphate-induced vascular smooth muscle cell calcification

(2016) Sophie Mokas et al.   KIDNEY INTERNATIONAL

O 2 sensing, mitochondria and ROS signaling: The fog is lifting

(2016) Gregory B. Waypa et al.   MOLECULAR ASPECTS OF MEDICINE

Redox signaling in cardiovascular pathophysiology: A focus on hydrogen peroxide and vascular smooth muscle cells

(2016) Chang Hyun Byon et al.   Redox Biology

Obstructive sleep apnea and abdominal aortic calcification: Is there an association independent of comorbid risk factors?

(2015) Ryo Tachikawa et al.   ATHEROSCLEROSIS

Oxygen Sensing by Arterial Chemoreceptors Depends on Mitochondrial Complex I Signaling

(2015) M. Carmen Fernández-Agüera et al.   Cell Metabolism

Bromodomain-Containing Protein 4Novelty and Significance

(2015) Jolyane Meloche et al.   CIRCULATION RESEARCH

Hypoxia and free radicals: Role in tumor progression and the use of engineering-based platforms to address these relationships

(2015) Abigail Hielscher et al.   FREE RADICAL BIOLOGY AND MEDICINE

Regulation of Hypoxia-Inducible Factor-1a by Reactive Oxygen Species : New Developments in an Old Debate

(2015) Shahrzad Movafagh et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

HIF-1α and VEGF: Immunohistochemical Profile and Possible Function in Human Aortic Valve Stenosis

(2015) Ida Perrotta et al.   ULTRASTRUCTURAL PATHOLOGY

Recent Highlights of ATVB: Calcification

(2014) R. Virmani et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The relationship between serum hypoxia-inducible factor 1α and coronary artery calcification in asymptomatic type 2 diabetic patients

(2014) Gang Li et al.   Cardiovascular Diabetology

NF-κB Directs Dynamic Super Enhancer Formation in Inflammation and Atherogenesis

(2014) Jonathan D. Brown et al.   MOLECULAR CELL

Coronary artery calcification is increased in patients with COPD and associated with increased morbidity and mortality

(2014) Michelle C Williams et al.   THORAX

Selective inhibition of BET bromodomain epigenetic signalling interferes with the bone-associated tumour vicious cycle

(2014) François Lamoureux et al.   Nature Communications

Red blood cell, hemoglobin and heme in the progression of atherosclerosis

(2014) Viktória Jeney et al.   Frontiers in Physiology

Coronary and carotid atherosclerosis: How useful is the imaging?

(2013) Pranvera Ibrahimi et al.   ATHEROSCLEROSIS

Vascular Calcification

(2013) Jane A. Leopold   CIRCULATION

Mechanistic Insights into Vascular Calcification in CKD

(2012) R. Shroff et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Hypoxia Promotes Osteogenesis but Suppresses Adipogenesis of Human Mesenchymal Stromal Cells in a Hypoxia-Inducible Factor-1 Dependent Manner

(2012) Markus Wagegg et al.   PLoS One

Tension in the Plaque: Hypoxia Modulates Metabolism in Atheroma

(2011) Peter Libby et al.   CIRCULATION RESEARCH

Mitochondrial reactive oxygen species promote p65 nuclear translocation mediating high-phosphate-induced vascular calcification in vitro and in vivo

(2011) Ming-Ming Zhao et al.   KIDNEY INTERNATIONAL

Vascular calcification: Inducers and inhibitors

(2011) Donghyun Lee   Materials Science and Engineering B-Advanced Functional Solid-State Materials

Osteogenic differences in cultured rat periosteal cells under hypoxic and normal conditions

(2011) TAKEHIRO ICHIJIMA et al.   Experimental and Therapeutic Medicine

Chronic Hypoxia Activates the Akt and β-Catenin Pathways in Human Macrophages

(2009) Jun-o Deguchi et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Mitochondrial reactive oxygen species regulate hypoxic signaling

(2009) Robert B Hamanaka et al.   CURRENT OPINION IN CELL BIOLOGY

Ferritin ferroxidase activity: A potent inhibitor of osteogenesis

(2009) Abolfazl Zarjou et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Vascular Calcification

(2008) Linda L. Demer et al.   CIRCULATION

A twist in the tail: synergism between mitochondria and NADPH oxidase in the hypoxia-induced elevation of reactive oxygen species in pulmonary artery☆

(2008) J WARD   FREE RADICAL BIOLOGY AND MEDICINE

Overexpression of hypoxia/inflammatory markers in atherosclerotic carotid plaques

(2008) Ana Luque   Frontiers in Bioscience-Landmark

Analysis of the Runx2 promoter in osseous and non-osseous cells and identification of HIF2A as a potent transcription activator

(2008) Hiroyuki Tamiya et al.   GENE

Oxidative Stress Induces Vascular Calcification through Modulation of the Osteogenic Transcription Factor Runx2 by AKT Signaling

(2008) Chang Hyun Byon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxidant Generation Predominates Around Calcifying Foci and Enhances Progression of Aortic Valve Calcification

(2007) Marcel Liberman et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY