In vitro Reconstitution of the Biosynthetic Pathway to the Nitroimidazole Antibiotic Azomycin

An N-nitrosating metalloenzyme constructs the pharmacophore of streptozotocin

(2019) Tai L. Ng et al.   NATURE

Two-Enzyme Pathway Links l-Arginine to Nitric Oxide in N-Nitroso Biosynthesis

(2019) Hai-Yan He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Snapshots of the Catalytic Cycle of an O2, Pyridoxal Phosphate-Dependent Hydroxylase

(2018) Jason B. Hedges et al.   ACS Chemical Biology

Streptomyces wadayamensis MppP is a PLP-Dependent Oxidase, Not an Oxygenase

(2018) Lanlan Han et al.   BIOCHEMISTRY

Dioxygen Activation by Nonheme Diiron Enzymes: Diverse Dioxygen Adducts, High-Valent Intermediates, and Related Model Complexes

(2018) Andrew J. Jasniewski et al.   CHEMICAL REVIEWS

Diiron monooxygenases in natural product biosynthesis

(2018) Anna J. Komor et al.   NATURAL PRODUCT REPORTS

Rieske non-heme iron-dependent oxygenases catalyse diverse reactions in natural product biosynthesis

(2018) Christopher Perry et al.   NATURAL PRODUCT REPORTS

Nitroimidazoles: Molecular Fireworks That Combat a Broad Spectrum of Infectious Diseases

(2017) Chee Wei Ang et al.   JOURNAL OF MEDICINAL CHEMISTRY

A pyridoxal phosphate–dependent enzyme that oxidizes an unactivated carbon-carbon bond

(2016) Yi-Ling Du et al.   Nature Chemical Biology

Streptomyces wadayamensis MppP Is a Pyridoxal 5′-Phosphate-Dependent l-Arginine α-Deaminase, γ-Hydroxylase in the Enduracididine Biosynthetic Pathway

(2015) Lanlan Han et al.   BIOCHEMISTRY

Mammalian dopa decarboxylase: Structure, catalytic activity and inhibition

(2014) Mariarita Bertoldi   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

CmlI is an N-oxygenase in the biosynthesis of chloramphenicol

(2012) Haige Lu et al.   TETRAHEDRON

Structural and Biochemical Studies of Human 4-hydroxy-2-oxoglutarate Aldolase: Implications for Hydroxyproline Metabolism in Primary Hyperoxaluria

(2011) Travis J. Riedel et al.   PLoS One

Naturally-occurring nitro compounds

(2010) Ronald Parry et al.   NATURAL PRODUCT REPORTS

Characterization of 3-Ketosteroid 9α-Hydroxylase, a Rieske Oxygenase in the Cholesterol Degradation Pathway ofMycobacterium tuberculosis

(2009) Jenna K. Capyk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In vitro reconstitution and crystal structure of p-aminobenzoate N-oxygenase (AurF) involved in aureothin biosynthesis

(2008) Y. S. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA