Efficient Phage Display with Multiple Distinct Non-Canonical Amino Acids Using Orthogonal Ribosome-Mediated Genetic Code Expansion

Playing with the Molecules of Life

(2018) Douglas D. Young et al.   ACS Chemical Biology

Rapid and Efficient Generation of Stable Antibody-Drug Conjugates via an Encoded Cyclopropene and an Inverse-Electron-Demand Diels-Alder Reaction

(2018) Benjamí Oller-Salvia et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mutually orthogonal pyrrolysyl-tRNA synthetase/tRNA pairs

(2018) Julian C. W. Willis et al.   Nature Chemistry

Highly multiplexed and quantitative cell-surface protein profiling using genetically barcoded antibodies

(2018) Samuel B. Pollock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expanding and reprogramming the genetic code

(2017) Jason W. Chin   NATURE

Continuous directed evolution of aminoacyl-tRNA synthetases

(2017) David I Bryson et al.   Nature Chemical Biology

Next generation antibody drugs: pursuit of the 'high-hanging fruit'

(2017) Paul J. Carter et al.   NATURE REVIEWS DRUG DISCOVERY

Evolution of thermophilic DNA polymerases for the recognition and amplification of C2ʹ-modified DNA

(2016) Tingjian Chen et al.   Nature Chemistry

Fast and Sequence-Specific Palladium-Mediated Cross-Coupling Reaction Identified from Phage Display

(2014) Reyna K. V. Lim et al.   ACS Chemical Biology

Expanding and Reprogramming the Genetic Code of Cells and Animals

(2014) Jason W. Chin   Annual Review of Biochemistry

Evolution of Iron(II)-Finger Peptides by Using a Bipyridyl Amino Acid

(2014) Mingchao Kang et al.   CHEMBIOCHEM

Concerted, Rapid, Quantitative, and Site-Specific Dual Labeling of Proteins

(2014) Amit Sachdeva et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Proteome labeling and protein identification in specific tissues and at specific developmental stages in an animal

(2014) Thomas S Elliott et al.   NATURE BIOTECHNOLOGY

Optimized orthogonal translation of unnatural amino acids enables spontaneous protein double-labelling and FRET

(2014) Kaihang Wang et al.   Nature Chemistry

Identification of metal ion binding peptides containing unnatural amino acids by phage display

(2013) Jonathan W. Day et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Phage display as a technology delivering on the promise of peptide drug discovery

(2013) Maryam Hamzeh-Mivehroud et al.   DRUG DISCOVERY TODAY

Nature-inspired design of motif-specific antibody scaffolds

(2013) James T Koerber et al.   NATURE BIOTECHNOLOGY

Quantitative Synthesis of Genetically Encoded Glycopeptide Libraries Displayed on M13 Phage

(2012) Simon Ng et al.   ACS Chemical Biology

Functionalized Cyclopropenes As Bioorthogonal Chemical Reporters

(2012) David M. Patterson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Phage display: Concept, innovations, applications and future

(2010) Jyoti Pande et al.   BIOTECHNOLOGY ADVANCES

Encoding multiple unnatural amino acids via evolution of a quadruplet-decoding ribosome

(2010) Heinz Neumann et al.   NATURE

Evolution of Proteins with Genetically Encoded “Chemical Warheads”

(2009) Chang C. Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Phage-encoded combinatorial chemical libraries based on bicyclic peptides

(2009) Christian Heinis et al.   Nature Chemical Biology

Rapid identification of reactive cysteine residues for site-specific labeling of antibody-Fabs

(2008) Jagath R. Junutula et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Protein evolution with an expanded genetic code

(2008) C. C. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA