Article
Chemistry, Analytical
Zihong Li, Jie Cheng, Ping Huang, Wenhui Song, Li Nong, Ling Huang, Weiying Lin
Summary: Hepatocellular carcinoma is a highly invasive malignant tumor of the liver, and studying the change in hepatocyte viscosity is crucial for the detection and treatment of liver cancer. Researchers have designed and synthesized the first hepatocyte-specific fluorescent probe for viscosity detection, which can be used for imaging liver cancer at both cellular and organ levels.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Songjiao Li, Peipei Wang, Ke Yang, Ying Liu, Dan Cheng, Longwei He
Summary: In order to improve the prognosis and overall survival of hepatocellular carcinoma (HCC) patients, it is important to identify and resect it at an early stage. However, developing specific fluorescent probes to detect hypochlorous acid (HClO) in liver cells is still challenging. Therefore, the development of a new probe MBH-MT that can detect HClO in biological samples and image it in cells and tissues is of great significance for the diagnosis and treatment of HCC.
ANALYTICA CHIMICA ACTA
(2023)
Article
Chemistry, Multidisciplinary
Nannan Zhu, Junhong Xu, Qiujuan Ma, Yang Geng, Linke Li, Shuzhen Liu, Shuangyu Liu, Gege Wang
Summary: The determination of mercuric ions (Hg2+) in environmental and biological samples has attracted researchers' attention lately. In this study, a novel turn-on Hg2+ fluorescent probe utilizing a rhodamine derivative has been constructed, which can sensitively and selectively sense Hg2+. The probe shows reversible dual colorimetric and fluorescence sensing of Hg2+ through forming a 1:1 coordination complex with Hg2+.
Article
Chemistry, Multidisciplinary
Huanyu Xie, Yudong Lu, Ruiyun You, Wei Qian, Shan Lin
Summary: In this study, nitrogen-doped graphene quantum dots (N-GQDs) were prepared and used for the detection of tetracycline (TC) based on the internal filtration effect. The method showed greenness, rapidity, high sensitivity, and selectivity, making it suitable for real food samples.
Article
Chemistry, Multidisciplinary
Xiangcao Li, Xuejian Xing, Shaojing Zhao, Shaohua Zhu, Benhua Wang, Minhuan Lan, Xiangzhi Song
Summary: In this study, a carbon dot-based fluorescent and colorimetric probe was developed for the visual, sensitive, and selective detection of benzoyl peroxide (BPO). The probe showed a short response time and high sensitivity, and demonstrated good applicability in wheat, noodle, and starch samples.
CHINESE CHEMICAL LETTERS
(2022)
Article
Chemistry, Multidisciplinary
Ying Wen, Ning Jing, Min Zhang, Fangjun Huo, Zhuoyu Li, Caixia Yin
Summary: This study developed a new fluorescent probe that can rapidly and selectively detect human carboxylesterase as a potential biomarker for hepatocellular carcinoma, improving the accuracy of diagnosis.
Review
Chemistry, Physical
Rui A. Goncalves, Krister Holmberg, Bjorn Lindman
Summary: This paper provides an overview of the self-assembly, intermolecular interactions, and properties of cationic surfactants, as well as their interactions with other solutes and surfaces. It also discusses the versatile properties of single-chain and double-chain cationic surfactants, as well as other special cationic surfactants, and their relationship with skin toxicity and environmental factors. Furthermore, the paper explores the mixing effects of cationic surfactants with other surfactants, polymers, proteins, and DNA, and outlines established and emerging applications of cationic surfactants.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Spectroscopy
Wenjin Sun, Ruizhen Li, Weifeng Liu, Xuguang Liu
Summary: A novel molecularly imprinted fluorescent nanopomegranate has been prepared for selective detection of quinoline in coking wastewater. The nanopomegranate exhibits excellent detection performance, high selectivity and affinity towards quinoline, as well as good reproducibility and anti-interference capability.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Chemistry, Analytical
Menghua Liu, Shuangying Li, Zhi Li, Yanhui Li, Yue Zhang, Jingwen Niu, Linchun Nie, Chunmao Chen, Qingxiang Zhou
Summary: This study explored the synthesis of carbon dots (CDs) from amoxicillin using a hydrothermal method. The obtained CDs exhibited good selectivity and sensitivity to benzidine and could be used as a fluorescence probe for monitoring benzidine in water samples.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Analytical
Surisa Sa-nguanprang, Anukorn Phuruangrat, Opas Bunkoed
Summary: A nanocomposite fluorescent probe was developed for the simultaneous determination of florfenicol and sparfloxacin through fluorescence quenching. The probe consisted of nitrogen-doped graphene quantum dots, cadmium telluride quantum dots, and zinc oxide nanoparticles integrated into a molecularly imprinted polymer. The probe showed high sensitivity and specificity, with good linear relationships and low limits of detection for both analytes. It was successfully applied to determine these antibiotics in food samples with good accuracy, precision, and recovery rates.
Article
Chemistry, Analytical
Ruru Gao, Junhong Wang, Han Wang, Wei Dong, Junwu Zhu
Summary: A new method based on coordination polymer nanoparticles for the selective and sensitive determination of aqueous 2,4,6-trinitrophenol has been established. The method shows good sensitivity and accuracy in real water samples, providing a feasible way to avoid the threat of contaminated drinking water.
Article
Spectroscopy
Yi Shu, Chaoqun Huang, Hongjing Liu, Feiyang Hu, Hongmei Wen, Jian Liu, Xinzhi Wang, Chenxiao Shan, Wei Li
Summary: In this study, a near-infrared (NIR) fluorescent probe named Lys-HXPI was designed and synthesized to effectively detect Carboxylesterases (CESs) and Histone deacetylases (HDACs), which are important signaling enzymes highly associated with the development and progression of multiple cancers, including hepatocellular carcinoma (HCC). The probe displayed strong NIR emission, low detection limits, high selectivity, and the ability to simultaneously image CESs and HDACs in living cells, tumor-bearing mice, and tissue slices.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Chemistry, Multidisciplinary
Chumki Dalal, Anjali Kumari Garg, Sumit Kumar Sonkar
Summary: In this study, a water-soluble beta-cyclodextrin-capped ZnO-doped carbon dot probe was synthesized for selective and sensitive detection of dopamine. The ZnO-CDs showed excellent emission properties and high quantum yield, with a detection limit of approximately 285 nM for dopamine. The probe demonstrated accuracy, selectivity, and sensitivity in detecting dopamine in spiked blood samples.
NEW JOURNAL OF CHEMISTRY
(2021)
Article
Spectroscopy
Meiju Tian, Junhong Xu, Qiujuan Ma, Linke Li, Hongmei Yuan, Jingguo Sun, Nannan Zhu, Shuzhen Liu
Summary: A lysosome-targeting fluorescent probe was developed for the selective detection of hydrogen polysulfides. The probe exhibited strong fluorescence in the presence of H2Sn and showed a good linear relationship and low detection limit. It had a wide pH working range, high selectivity for H2Sn, and could detect H2Sn intracellularly and extracellularly.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Chemistry, Multidisciplinary
Dipankar Bain, Aarti Devi, Sikta Chakraborty, Amitava Patra
Summary: We designed a fluorescent probe, poly(allylamine) hydrochloride (PAH) functionalized copper nanocluster (Cu NC@PAH), for the selective detection of sulfide (S2-) ions in water. The probe showed a significant enhancement in photoluminescence (PL) intensity and quantum yield (QY) after functionalizing with the cationic polymer PAH. The probe also exhibited excellent selectivity and a reasonable quenching response for S2- ions, with a detection limit of 2.39 μM.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2023)
Article
Chemistry, Analytical
Hakan Berk Aydin, Jamal Ahmed Cheema, Gopal Arnmanath, Cihan Toklucu, Muge Yucel, Sezer Ozenler, Alagappan Palaniappan, Bo Liedberg, Umit Hakan Yildiz
Article
Chemistry, Multidisciplinary
Sezer Ozenler, Yigit Sozen, Hasan Sahin, Umit Hakan Yildiz
Article
Chemistry, Physical
Sahika Ozguler, Halide Diker, Secil Sevim Unluturk, Serdar Ozcelik, Canan Varlikli
JOURNAL OF PHYSICAL CHEMISTRY C
(2020)
Article
Nanoscience & Nanotechnology
Serdar Ozcelik, Guillem Pratx
Article
Nanoscience & Nanotechnology
Secil Sevim Unluturk, Yasar Akdogan, Serdar Ozcelik
Summary: The study introduces a facile method for preparing magnetically active ultraviolet emitting manganese ions incorporated ZnSxSe1-x colloidal quantum dots (nanoalloys) in aqueous solutions, emphasizing the main factors influencing alloy composition and size. The research also reveals that the incorporation of Mn2+ ions into the nanoalloys can induce magnetic activity without altering their structure and photophysical properties.
Article
Materials Science, Biomaterials
Ozge Tuncel, Erkan Kahraman, Gulsun Bagci, Nese Atabey, Serdar Ozcelik
Summary: This study synthesized and characterized silica nanoparticles of different sizes, finding that they are not toxic to human liver cells and endothelial cells, and do not affect cell proliferation or red blood cell hemolysis activity.
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
(2021)
Article
Chemistry, Multidisciplinary
Muge Yucel, Altug Koc, Ayfer Ulgenalp, Gun Deniz Akkoc, Metin Ceyhan, Umit Hakan Yildiz
Summary: This study presents a nonamplification-based nucleic acid assay for the rapid screening of familial Mediterranean fever, showing significant potential for cost-effective and efficient screening. Through analysis using principal component analysis and support vector machine classification, the assay showed 96% overall accuracy, demonstrating its effectiveness in detecting FMF.
Article
Chemistry, Physical
Secil Sevim Unluturk, Ali Cagir, Canan Varlikli, Serdar Ozcelik
Summary: Impurities in trioctylphophine (TOP), specifically the presence of 1-octanol, have been shown to significantly impact the synthesis and photophysical properties of ZnCdSSe/ZnS colloidal nanocrystals. The deliberate addition of 1-octanol into TOP results in smaller particle size and modified spectral shifts, while also increasing nonradiative processes within the nanocrystals. This study suggests that 1-octanol plays a critical role as a functional impurity in tuning the particle size and photophysical processes of the nanocrystals.
JOURNAL OF PHYSICAL CHEMISTRY C
(2021)
Article
Chemistry, Multidisciplinary
Oyku Yildirimkaraman, Sezer Oezenler, Ufuk Saim Gunay, Hakan Durmaz, Umit Hakan Yildiz
Summary: The research demonstrates the formation of a nanogel coating on a gold surface using reactive layer-by-layer assembly, which exhibits multilayered structure, uniform distribution, and good electrochemical properties. The nanogel coating based on rLBL reactions effectively drives mass and charge transfer, making it suitable for applications in soft biointerfaces.
Article
Nanoscience & Nanotechnology
Didem Tascioglu, Arda Atci, Secil Sevim Unluturk, Serdar Ozcelik
Summary: Counterfeiting is a growing problem, and this study proposes an anticounterfeiting technology that utilizes random and inimitable patterns as security tags. The patterns are detectable under UV light and invisible in daylight. By collecting images of the patterns using a smartphone microscope, a database of original patterns is created for authenticity verification. Additionally, a handheld spectrometer is used to obtain the spectral signature of the patterns, enabling a second-step verification. This technology combines ink formula, unclonable security pattern creation, and two-level verification for effective anticounterfeiting.
Article
Chemistry, Multidisciplinary
Emel Onal, Ozge Tuncel, Ipek Erdogan Vatansever, Mohamad Albakour, Gizem Gumusgoz Celik, Tugba Kucuk, Bunyamin Akgul, Ayse Gul Gurek, Serdar Ozcelik
Summary: Novel mitochondrion-targeted phthalocyanine and porphyrin photosensitizers were synthesized and their photophysical and photochemical properties were defined. The TPP-conjugated porphyrin and phthalocyanine PSs showed high singlet oxygen generation capacity and effectively killed the cells.
Article
Cell Biology
Azime Akcaoz Alasar, Ozge Tuncel, Ayse Bengisu Gelmez, Buket Saglam, Ipek Erdogan Vatansever, Bunyamin Akgul
Summary: The effect of m(6)A methylation marks on cisplatin-induced apoptosis was investigated using an m(6)A miCLIP-seq approach. The study revealed the modulation of apoptotic pathways by m(6)A methylation events and the regulation of cisplatin-mediated apoptosis by the METTL3-PMAIP1 axis.
Article
Materials Science, Multidisciplinary
Didem Tascioglu, Secil Sevim unluturk, Serdar ozcelik
Summary: This technology utilizes custom-formulated fluorescent inks and a handheld optical device to identify nearly invisible security patterns under UV-light. By adjusting the concentration of nanoparticles in the ink, the patterns can be made almost imperceptible under UV-light but still recognizable by professional spectrometers and handheld optical devices.
MATERIALS ADVANCES
(2021)
Article
Chemistry, Multidisciplinary
Emel Onal, Ozge Tuncel, Mohamad Albakour, Gizem Gumusgoz Celik, Ayse Gul Gurek, Serdar Ozcelik
Summary: Heteroleptic A(7)B type novel Lu(iii) and Eu(iii) lanthanide phthalocyanines with high extinction coefficients have been synthesized as candidate photosensitizers with reaction yields higher than 33%. The singlet oxygen quantum yields were measured and LuPc(Pox)[Pc '(AB(3)SH)] showed the highest quantum yield among lutetium(iii) bis-phthalocyanine complexes to date. Cell viability measurements on A549 and BEAS-2B lung cells demonstrated concentration dependent behavior and promising photodynamic efficacy of LuPc(Pox)[Pc '(AB(3)SH)].
