LW-213, a newly synthesized flavonoid, induces G2/M phase arrest and apoptosis in chronic myeloid leukemia

CD34+CD38− leukemic stem cell frequency to predict outcome in acute myeloid leukemia

(2018) Wendelien Zeijlemaker et al.   LEUKEMIA

CDK9-dependent RNA polymerase II pausing controls transcription initiation

(2017) Saskia Gressel et al.   eLife

Bladder cancer cell viability inhibition and apoptosis induction by baicalein through targeting the expression of anti-apoptotic genes

(2017) Yong Yang et al.   SAUDI JOURNAL OF BIOLOGICAL SCIENCES

Crosstalk Between the Autophagy-Lysosome Pathway and the Ubiquitin-Proteasome Pathway in Retinal Pigment Epithelial Cells

(2016) J. Zhan et al.   CURRENT MOLECULAR MEDICINE

Modulation of Glucocorticoid Resistance in Pediatric T-cell Acute Lymphoblastic Leukemia by Increasing BIM Expression with the PI3K/mTOR Inhibitor BEZ235

(2015) C. P. Hall et al.   CLINICAL CANCER RESEARCH

Mechanisms of resistance to BCR–ABL TKIs and the therapeutic strategies: A review

(2015) Ke Yang et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Chronic myeloid leukaemia

(2015) Jane F Apperley   LANCET

LW-213 induces G2/M cell cycle arrest through AKT/GSK3β/β-catenin signaling pathway in human breast cancer cells

(2015) Li Zhao et al.   MOLECULAR CARCINOGENESIS

Leukemia stem cells: the root of chronic myeloid leukemia

(2015) Hong Zhou et al.   Protein & Cell

Wogonoside induces cell cycle arrest and differentiation by affecting expression and subcellular localization of PLSCR1 in AML cells

(2013) Y. Chen et al.   BLOOD

Targeting acute myeloid leukemia by dual inhibition of PI3K signaling and Cdk9-mediated Mcl-1 transcription

(2013) D. Thomas et al.   BLOOD

Activity of the pan-class I phosphoinositide 3-kinase inhibitor NVP-BKM120 in T-cell acute lymphoblastic leukemia

(2013) A Lonetti et al.   LEUKEMIA

Wogonin and related natural flavones are inhibitors of CDK9 that induce apoptosis in cancer cells by transcriptional suppression of Mcl-1

(2011) G Polier et al.   Cell Death & Disease

Mcl-1 is a potential therapeutic target in multiple types of cancer

(2008) C. Akgul   CELLULAR AND MOLECULAR LIFE SCIENCES

Unique Biology of Mcl-1: Therapeutic Opportunities in Cancer

(2008) Gordon Shore et al.   CURRENT MOLECULAR MEDICINE