LW-213 induces G2/M cell cycle arrest through AKT/GSK3β/β-catenin signaling pathway in human breast cancer cells

LL-202, a newly synthesized flavonoid, inhibits tumor growth via inducing G2/M phase arrest and cell apoptosis in MCF-7 human breast cancer cells in vitro and in vivo

(2014) Lei Tao et al.   TOXICOLOGY LETTERS

MUC4-induced nuclear translocation of β-catenin: A novel mechanism for growth, metastasis and angiogenesis in pancreatic cancer

(2013) Xiaofei Zhi et al.   CANCER LETTERS

Upregulated microRNA-301a in breast cancer promotes tumor metastasis by targeting PTEN and activating Wnt/β-catenin signaling

(2013) Fei Ma et al.   GENE

Wogonin reverses hypoxia resistance of human colon cancer HCT116 cells via downregulation of HIF-1α and glycolysis, by inhibiting PI3K/Akt signaling pathway

(2013) Hu Wang et al.   MOLECULAR CARCINOGENESIS

Wogonin induced G1 cell cycle arrest by regulating Wnt/β-catenin signaling pathway and inactivating CDK8 in human colorectal cancer carcinoma cells

(2013) Licheng He et al.   TOXICOLOGY

Reactive oxygen species mediate Cr(VI)-induced carcinogenesis through PI3K/AKT-dependent activation of GSK-3β/β-catenin signaling

(2013) Young-Ok Son et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

GSK3β/β-catenin signaling is correlated with the differentiation of glioma cells induced by wogonin

(2013) Yajing Wang et al.   TOXICOLOGY LETTERS

Oroxylin A reverses P-glycoprotein-mediated multidrug resistance of MCF7/ADR cells by G2/M arrest

(2013) Litao Zhu et al.   TOXICOLOGY LETTERS

Biphasic Dose-Dependent Effect of Lithium Chloride on Survival of Human Hormone-Dependent Breast Cancer Cells (MCF-7)

(2012) Muralidharan Suganthi et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Hedgehog and Wnt coordinate signaling in myogenic progenitors and regulate limb regeneration

(2012) Bhairab N. Singh et al.   DEVELOPMENTAL BIOLOGY

Cannabisin B induces autophagic cell death by inhibiting the AKT/mTOR pathway and S phase cell cycle arrest in HepG2 cells

(2012) Tianpeng Chen et al.   FOOD CHEMISTRY

Cadmium induces carcinogenesis in BEAS-2B cells through ROS-dependent activation of PI3K/AKT/GSK-3β/β-catenin signaling

(2012) Young-Ok Son et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Anti-proliferative effect of (19Z)-halichondramide, a novel marine macrolide isolated from the sponge Chondrosia corticata, is associated with G2/M cell cycle arrest and suppression of mTOR signaling in human lung cancer cells

(2012) Song Yi Bae et al.   TOXICOLOGY IN VITRO

Antitumor effects of a novel benzonaphthofurandione derivative (8e) on the human colon cancer cells in vitro and in vivo through cell cycle arrest accompanied with the modulation of EGFR and mTOR signaling

(2011) Hwa-Jin Chung et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Wogonin induces apoptosis and down-regulates survivin in human breast cancer MCF-7 cells by modulating PI3K–AKT pathway

(2011) K.F. Huang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Inhibitory effects of wogonin on the invasion of human breast carcinoma cells by downregulating the expression and activity of matrix metalloproteinase-9

(2011) Pu Chen et al.   TOXICOLOGY

Combined targeting of the VEGFr/EGFr and the mammalian target of rapamycin (mTOR) signaling pathway delays cell cycle progression and alters adhesion behavior of prostate carcinoma cells

(2010) Steffen Wedel et al.   CANCER LETTERS

The effect of Li+ on GSK-3 inhibition: Molecular dynamics simulation

(2010) Hao Sun et al.   JOURNAL OF MOLECULAR MODELING

mTOR: from growth signal integration to cancer, diabetes and ageing

(2010) Roberto Zoncu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Wogonin induces G1 phase arrest through inhibiting Cdk4 and cyclin D1 concomitant with an elevation in p21Cip1 in human cervical carcinoma HeLa cells

(2009) Li Yang et al.   Biochemistry and Cell Biology

Wnt signalling and cancer stem cells

(2009) Jesús Espada et al.   Clinical & Translational Oncology

Crosstalk of hedgehog and Wnt pathways in gastric cancer

(2008) Kosuke Yanai et al.   CANCER LETTERS

New therapeutic aspects of flavones: The anticancer properties of Scutellaria and its main active constituents Wogonin, Baicalein and Baicalin

(2008) Min Li-Weber   CANCER TREATMENT REVIEWS

Wogonin induced differentiation and G1 phase arrest of human U-937 leukemia cells via PKCδ phosphorylation

(2008) Hai-Wei Zhang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

DNA damage, signalling and repair after exposure of cells to the sulphur mustard analogue 2-chloroethyl ethyl sulphide

(2008) Paul A. Jowsey et al.   TOXICOLOGY