Somatic and germline mutations in the tumor suppressor gene PARK2 impair PINK1/Parkin-mediated mitophagy in lung cancer cells

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Dynasore Suppresses mTORC1 Activity and Induces Autophagy to Regulate the Clearance of Protein Aggregates in Neurodegenerative Diseases

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MicroRNA-26a/Death-associated protein kinase 1 signaling induces synucleinopathy and dopaminergic neuron degeneration in Parkinson’s disease

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Dynamic recruitment and activation of ALS-associated TBK1 with its target optineurin are required for efficient mitophagy

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A Recurrent Mutation in PARK2 Is Associated with Familial Lung Cancer

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Nucleolar stress and impaired stress granule formation contribute to C9orf72 RAN translation-induced cytotoxicity

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MiT/TFE transcription factors are activated during mitophagy downstream of Parkin and Atg5

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The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

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Endogenous Parkin Preserves Dopaminergic Substantia Nigral Neurons following Mitochondrial DNA Mutagenic Stress

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PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity

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Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation

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Bcl-2-dependent upregulation of autophagy by sequestosome 1/p62 in vitro

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Loss of iron triggers PINK1/Parkin-independent mitophagy

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Parkin Pathway Activation Mitigates Glioma Cell Proliferation and Predicts Patient Survival

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Ataxin-3 Regulates Aggresome Formation of Copper-Zinc Superoxide Dismutase (SOD1) by Editing K63-linked Polyubiquitin Chains

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Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy

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The Endoplasmic Reticulum (ER)-associated Degradation System Regulates Aggregation and Degradation of Mutant Neuroserpin

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Parkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effect

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p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both

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