Metformin‐induced autophagy and irisin improves INS‐1 cell function and survival in high‐glucose environment via AMPK/SIRT1/PGC‐1α signal pathway

Autophagy Is a Promoter for Aerobic Exercise Performance during High Altitude Training

(2018) Ying Zhang et al.   Oxidative Medicine and Cellular Longevity

A reappraisal on metformin

(2018) Tuğba Adak et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

A Novel Regulator of Type II Diabetes: MicroRNA-143

(2018) Biao Li et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Cytoprotective effect of kaempferol against palmitic acid-induced pancreatic β-cell death through modulation of autophagy via AMPK/mTOR signaling pathway

(2017) Ritu Varshney et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Erratum to: Treadmill Exercise Attenuates α-Synuclein Levels by Promoting Mitochondrial Function and Autophagy Possibly via SIRT1 in the Chronic MPTP/P-Induced Mouse Model of Parkinson’s Disease

(2017) Jung-Hoon Koo et al.   NEUROTOXICITY RESEARCH

Effects and underlying mechanisms of irisin on the proliferation and apoptosis of pancreatic β cells

(2017) Shiwei Liu et al.   PLoS One

Resveratrol as a Natural Autophagy Regulator for Prevention and Treatment of Alzheimer’s Disease

(2017) et al.   Nutrients

Dissecting the role of AMP-activated protein kinase in human diseases

(2017) Jin Li et al.   Acta Pharmaceutica Sinica B

Dipeptidyl peptidase-4 inhibitor MK-626 restores insulin secretion through enhancing autophagy in high fat diet-induced mice

(2016) Limei Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Melatonin-Mediated Intracellular Insulin during 2-Deoxy-d-glucose Treatment Is Reduced through Autophagy and EDC3 Protein in Insulinoma INS-1E Cells

(2016) Han Sung Kim et al.   Oxidative Medicine and Cellular Longevity

Pancreatic β Cell Mass Death

(2016) Husnia I. Marrif et al.   Frontiers in Pharmacology

5'-Monophosphate-activated protein kinase (AMPK) improves autophagic activity in diabetes and diabetic complications

(2016) Fan Yao et al.   Acta Pharmaceutica Sinica B

Irisin inhibits hepatic gluconeogenesis and increases glycogen synthesis via the PI3K/Akt pathway in type 2 diabetic mice and hepatocytes

(2015) T.-Y. Liu et al.   CLINICAL SCIENCE

Irisin, an exercise-induced myokine as a metabolic regulator: an updated narrative review

(2015) Ning Chen et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Functionalized self-assembling peptide improves INS-1 β-cell function and proliferation via the integrin/FAK/ERK/cyclin pathway

(2015) Jingping Liu et al.   International Journal of Nanomedicine

Autophagy as a Potential Target for Sarcopenia

(2015) Jingjing Fan et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Cyclic AMP Mimics the Anti-ageing Effects of Calorie Restriction by Up-Regulating Sirtuin

(2015) Zhuoran Wang et al.   Scientific Reports

Metformin Plays a Dual Role in MIN6 Pancreatic β Cell Function through AMPK-dependent Autophagy

(2014) Yingling Jiang et al.   International Journal of Biological Sciences

Amyloidogenic peptide oligomer accumulation in autophagy-deficient β cells induces diabetes

(2014) Jinyoung Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Autophagy in drug-induced liver toxicity

(2014) Si Chen et al.   JOURNAL OF FOOD AND DRUG ANALYSIS

Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013

(2014) Marie Ng et al.   LANCET

PPARγ and PGC-1α as Therapeutic Targets in Parkinson’s

(2014) Juan Carlos Corona et al.   NEUROCHEMICAL RESEARCH

A comprehensive immunohistochemical examination of the distribution of the fat-burning protein irisin in biological tissues

(2014) Suleyman Aydin et al.   PEPTIDES

Higher baseline irisin concentrations are associated with greater reductions in glycemia and insulinemia after weight loss in obese subjects

(2014) P Lopez-Legarrea et al.   Nutrition & Diabetes

Loss of Pgc-1α expression in aging mouse muscle potentiates glucose intolerance and systemic inflammation

(2013) Sarah Sczelecki et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

AMPK, insulin resistance, and the metabolic syndrome

(2013) Neil B. Ruderman et al.   JOURNAL OF CLINICAL INVESTIGATION

SIRT1 interacts with metabolic transcriptional factors in the pancreas of insulin-resistant and calorie-restricted rats

(2013) Yong-Ru Chen et al.   MOLECULAR BIOLOGY REPORTS

Role of Exercise in the Management of Diabetes Mellitus: the Global Scenario

(2013) Zar Chi Thent et al.   PLoS One

Liver-Derived Systemic Factors Drive β Cell Hyperplasia in Insulin-Resistant States

(2013) Abdelfattah El Ouaamari et al.   Cell Reports

Activation of SIRT1 protects pancreatic β-cells against palmitate-induced dysfunction

(2012) Ling Wu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

(2012) Pontus Boström et al.   NATURE

Metformin prevents endoplasmic reticulum stress-induced apoptosis through AMPK-PI3K-c-Jun NH2 pathway

(2011) Tae Woo Jung et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Autophagy as a therapeutic target in cancer

(2011) Ning Chen et al.   CANCER BIOLOGY & THERAPY

Endurance training stimulates growth and survival pathways and the redox balance in rat pancreatic islets

(2011) Vivian C. Calegari et al.   JOURNAL OF APPLIED PHYSIOLOGY

Exercise and T2DM—move muscles more often!

(2011) David Dunstan   Nature Reviews Endocrinology

The role of autophagy in β-cell lipotoxicity and type 2 diabetes

(2010) G. Las et al.   DIABETES OBESITY & METABOLISM

Resveratrol Potentiates Glucose-stimulated Insulin Secretion in INS-1E β-Cells and Human Islets through a SIRT1-dependent Mechanism

(2010) Laurène Vetterli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role and regulation of autophagy in cancer

(2009) Ning Chen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Autophagy in aging, disease and death: the true identity of a cell death impostor

(2008) B Levine et al.   CELL DEATH AND DIFFERENTIATION

Overexpression of SIRT1 Protects Pancreatic  -Cells Against Cytokine Toxicity by Suppressing the Nuclear Factor- B Signaling Pathway

(2008) J.-H. Lee et al.   DIABETES

Epigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretion

(2008) C. Ling et al.   DIABETOLOGIA