Heparanase Promotes Tumor Growth and Liver Metastasis of Colorectal Cancer Cells by Activating the p38/MMP1 Axis

Gemcitabine-induced heparanase promotes aggressiveness of pancreatic cancer cells via activating EGFR signaling

(2017) Jin-Wen Song et al.   Oncotarget

Heparanase regulation of cancer, autophagy and inflammation: new mechanisms and targets for therapy

(2016) Ralph D. Sanderson et al.   FEBS Journal

Global patterns and trends in colorectal cancer incidence and mortality

(2016) Melina Arnold et al.   GUT

Heparanase Promotes Glioma Progression and Is Inversely Correlated with Patient Survival

(2016) Soumi Kundu et al.   MOLECULAR CANCER RESEARCH

Heparanase-neutralizing antibodies attenuate lymphoma tumor growth and metastasis

(2016) Marina Weissmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heparanase is involved in proliferation and invasion of ovarian cancer cells

(2015) Haiyan Zheng et al.   Cancer Biomarkers

Nicotine enhances invasion and metastasis of human colorectal cancer cells through the nicotinic acetylcholine receptor downstream p38 MAPK signaling pathway

(2015) TAO XIANG et al.   ONCOLOGY REPORTS

The potential of heparanase as a therapeutic target in cancer

(2014) Claudio Pisano et al.   BIOCHEMICAL PHARMACOLOGY

Development and Applications of CRISPR-Cas9 for Genome Engineering

(2014) Patrick D. Hsu et al.   CELL

The Role of Matrix Metalloproteinases in Colorectal Cancer

(2014) Anan Said et al.   Cancers

The Role of Heparanase and Sulfatases in the Modification of Heparan Sulfate Proteoglycans within the Tumor Microenvironment and Opportunities for Novel Cancer Therapeutics

(2014) Edward Hammond et al.   Frontiers in Oncology

Downregulation of heparanase by RNA interference inhibits invasion and tumorigenesis of hepatocellular cancer cells in vitro and in vivo

(2012) Chuan Li   INTERNATIONAL JOURNAL OF ONCOLOGY

Comparison of Adjuvant Systemic Chemotherapy With or Without Hepatic Arterial Infusional Chemotherapy After Hepatic Resection for Metastatic Colorectal Cancer

(2011) Michael G. House et al.   ANNALS OF SURGERY

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Small RNA interference-mediated gene silencing of heparanase abolishes the invasion, metastasis and angiogenesis of gastric cancer cells

(2010) Liduan Zheng et al.   BMC CANCER

Heparanase: busy at the cell surface

(2009) Liat Fux et al.   TRENDS IN BIOCHEMICAL SCIENCES

Heparanase Stimulation of Protease Expression Implicates It as a Master Regulator of the Aggressive Tumor Phenotype in Myeloma

(2008) Anurag Purushothaman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY