The Role of Nonerythroid Spectrin αII in Cancer

Downregulation of SPTAN1 is related to MLH1 deficiency and metastasis in colorectal cancer

(2019) Anne Ackermann et al.   PLoS One

Bicalutamide enhances fodrin-mediated apoptosis through calpain in LNCaP

(2018) Jiyeong Lee et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Replication-incompetent gammaretroviral and lentiviral vector-based insertional mutagenesis screens identify prostate cancer progression genes

(2018) Victor M. Bii et al.   Oncotarget

Novel variants in SPTAN1 without epilepsy: An expansion of the phenotype

(2018) Valerie Gartner et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

MLH1 enhances the sensitivity of human endometrial carcinoma cells to cisplatin by activating the MLH1/c-Abl apoptosis signaling pathway

(2018) Yue Li et al.   BMC CANCER

αII-spectrin in T cells is involved in the regulation of cell-cell contact leading to immunological synapse formation?

(2017) Justyna M. Meissner et al.   PLoS One

Identification of a novel CSF3R-SPTAN1 fusion gene in an atypical chronic myeloid leukemia patient with t(1;9)(p34;q34) by RNA-Seq

(2017) Guangying Sheng et al.   Cancer Genetics

Adducin in tumorigenesis and metastasis

(2017) Cong Luo et al.   Oncotarget

A systems medicine approach for finding target proteins affecting treatment outcomes in patients with non-Hodgkin lymphoma

(2017) Faezeh Ajorloo et al.   PLoS One

Nuclear alpha spectrin: Critical roles in DNA interstrand cross-link repair and genomic stability

(2016) Muriel W Lambert   EXPERIMENTAL BIOLOGY AND MEDICINE

Cytoskeletal Integrators: The Spectrin Superfamily

(2016) Ronald K.H. Liem   Cold Spring Harbor Perspectives in Biology

MicroRNA-128-3p regulates mitomycin C-induced DNA damage response in lung cancer cells through repressing SPTAN1

(2016) Rui Zhang et al.   Oncotarget

Dlc1 interaction with non-muscle myosin heavy chain II-A (Myh9) and Rac1 activation

(2016) Mohammad G. Sabbir et al.   Biology Open

Spectrin’s chimeric E2/E3 enzymatic activity

(2015) Steven R Goodman et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

SPTAN1 encephalopathy: distinct phenotypes and genotypes

(2015) Jun Tohyama et al.   JOURNAL OF HUMAN GENETICS

FAK signaling in human cancer as a target for therapeutics

(2015) Brian Y. Lee et al.   PHARMACOLOGY & THERAPEUTICS

Heat-Modified Citrus Pectin Induces Apoptosis-Like Cell Death and Autophagy in HepG2 and A549 Cancer Cells

(2015) Lionel Leclere et al.   PLoS One

Conserved recurrent gene mutations correlate with pathway deregulation and clinical outcomes of lung adenocarcinoma in never-smokers

(2014) Zhifu Sun et al.   BMC Medical Genomics

MicroRNA-128-3p is a novel oncomiR targeting PHF6 in T-cell acute lymphoblastic leukemia

(2014) E. Mets et al.   HAEMATOLOGICA

EspC Promotes Epithelial Cell Detachment by Enteropathogenic Escherichia coli via Sequential Cleavages of a Cytoskeletal Protein and then Focal Adhesion Proteins

(2014) F. Navarro-Garcia et al.   INFECTION AND IMMUNITY

Reduced migration of MLH1 deficient colon cancer cells depends on SPTAN1

(2014) Inga Hinrichsen et al.   Molecular Cancer

Chromosome 9q33q34 Microdeletion With Early Infantile Epileptic Encephalopathy, Severe Dystonia, Abnormal Eye Movements, and Nephroureteral Malformations

(2014) Hiroshi Matsumoto et al.   PEDIATRIC NEUROLOGY

Identification of Genes Associated with Local Aggressiveness and Metastatic Behavior in Soft Tissue Tumors

(2014) Isabela Werneck Cunha et al.   Translational Oncology

Spectrins: A structural platform for stabilization and activation of membrane channels, receptors and transporters

(2013) Beata Machnicka et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Proteogenomic Analysis of Human Colon Carcinoma Cell Lines LIM1215, LIM1899, and LIM2405

(2013) Susan Fanayan et al.   JOURNAL OF PROTEOME RESEARCH

Non-erythroid alpha spectrin prevents telomere dysfunction after DNA interstrand cross-link damage

(2013) Pan Zhang et al.   NUCLEIC ACIDS RESEARCH

Caspase-2 Short Isoform Interacts with Membrane-Associated Cytoskeleton Proteins to Inhibit Apoptosis

(2013) Chunhua Han et al.   PLoS One

Identification of a novel in-frame de novo mutation in SPTAN1 in intellectual disability and pontocerebellar atrophy

(2012) Fadi F Hamdan et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Novel 9q34.11 gene deletions encompassing combinations of four Mendelian disease genes: STXBP1, SPTAN1, ENG and TOR1A

(2012) Ian M. Campbell et al.   GENETICS IN MEDICINE

Hypoxia-Induced Alternative Splicing in Endothelial Cells

(2012) Julia E. Weigand et al.   PLoS One

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Spectrin-based skeleton as an actor in cell signaling

(2011) B. Machnicka et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Genes of Early-Onset Epileptic Encephalopathies: From Genotype to Phenotype

(2011) Mario Mastrangelo et al.   PEDIATRIC NEUROLOGY

Dominant-Negative Mutations in α-II Spectrin Cause West Syndrome with Severe Cerebral Hypomyelination, Spastic Quadriplegia, and Developmental Delay

(2010) Hirotomo Saitsu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Aggregation of spectrin and PKCθ is an early hallmark of fludarabine/mitoxantrone/dexamethasone-induced apoptosis in Jurkat T and HL60 cells

(2010) Patrycja M. Dubielecka et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Cytoskeletal scaffolding proteins interact with Lynch-Syndrome associated mismatch repair protein MLH1

(2010) Angela Brieger et al.   PROTEOMICS

The spectrin–ankyrin–4.1–adducin membrane skeleton: adapting eukaryotic cells to the demands of animal life

(2010) Anthony J. Baines   PROTOPLASMA

Knockdown of αII spectrin in normal human cells by siRNA leads to chromosomal instability and decreased DNA interstrand cross-link repair

(2009) Laura W. McMahon et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Podosome-like structures of non-invasive carcinoma cells are replaced in epithelial-mesenchymal transition by actin comet-embedded invadopodia

(2009) Minna Takkunen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Chemical Induction of Cardiac Differentiation in P19 Embryonal Carcinoma Stem Cells

(2009) Jasmin et al.   STEM CELLS AND DEVELOPMENT

The SH3 Domain of αII Spectrin Is a Target for the Fanconi Anemia Protein, FANCG†

(2008) Joel A. Lefferts et al.   BIOCHEMISTRY

αII-Spectrin Is Critical for Cell Adhesion and Cell Cycle

(2008) Sylvain Metral et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cytoskeleton assembly at endothelial cell–cell contacts is regulated by αII-spectrin–VASP complexes

(2008) Peter M. Benz et al.   JOURNAL OF CELL BIOLOGY

Prostaglandin-induced VASP phosphorylation controls αII-spectrin breakdown in apoptotic cells

(2007) Peter M. Benz et al.   INTERNATIONAL IMMUNOPHARMACOLOGY