Deubiquitinase DUB3 Regulates Cell Cycle Progression via Stabilizing Cyclin A for Proliferation of Non-Small Cell Lung Cancer Cells

Deubiquitylation and stabilization of p21 by USP11 is critical for cell-cycle progression and DNA damage responses

(2018) Tanggang Deng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Ubiquitin–Proteasome Axis, Especially Ubiquitin-Specific Protease-17 (USP17) Gene Family, is a Potential Target for Epithelial–Mesenchymal Transition in High-Grade Serous Ovarian Cancer

(2018) Nuri Yildirim et al.   Reproductive Sciences

CDK4/6 inhibition stabilizes disease in patients with p16-null non-small cell lung cancer and is synergistic with mTOR inhibition

(2018) Priya K. Gopalan et al.   Oncotarget

USP17 is upregulated in osteosarcoma and promotes cell proliferation, metastasis, and epithelial–mesenchymal transition through stabilizing SMAD4

(2017) Chenyang Song et al.   TUMOR BIOLOGY

CDK4/6-dependent activation of DUB3 regulates cancer metastasis through SNAIL1

(2017) Tongzheng Liu et al.   Nature Communications

Expression and functional implications of USP17 in glioma

(2016) Manmiao Hu et al.   NEUROSCIENCE LETTERS

Suppression of Ubiquitin-Specific Peptidase 17 (USP17) Inhibits Tumorigenesis and Invasion in Non-Small Cell Lung Cancer Cells

(2016) Shengchao Zhang et al.   ONCOLOGY RESEARCH

PIWIL2 promotes progression of non-small cell lung cancer by inducing CDK2 and Cyclin A expression

(2015) Xiaohan Qu et al.   Journal of Translational Medicine

The deubiquitinating enzyme USP17 is associated with non-small cell lung cancer (NSCLC) recurrence and metastasis

(2015) Cheryl McFarlane et al.   Oncotarget

Cell Cycle-Dependent Expression of Dub3, Nanog and the p160 Family of Nuclear Receptor Coactivators (NCoAs) in Mouse Embryonic Stem Cells

(2014) Siem van der Laan et al.   PLoS One

Deubiquitinase USP37 Is Activated by CDK2 to Antagonize APCCDH1 and Promote S Phase Entry

(2011) XiaoDong Huang et al.   MOLECULAR CELL

Deubiquitinases in cancer: new functions and therapeutic options

(2011) J M Fraile et al.   ONCOGENE

The Deubiquitinating Enzyme USP17 Is Highly Expressed in Tumor Biopsies, Is Cell Cycle Regulated, and Is Required for G1-S Progression

(2010) C. McFarlane et al.   CANCER RESEARCH

Ubiquitin hydrolase Dub3 promotes oncogenic transformation by stabilizing Cdc25A

(2010) Yaron Pereg et al.   NATURE CELL BIOLOGY

Degradation of cyclin A is regulated by acetylation

(2009) F Mateo et al.   ONCOGENE