Zebrafish Carrying pycr1 Gene Deficiency Display Aging and Multiple Behavioral Abnormalities

Zinc Chloride Exposure Inhibits Brain Acetylcholine Levels, Produces Neurotoxic Signatures, and Diminishes Memory and Motor Activities in Adult Zebrafish

(2018) Sreeja Sarasamma et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Evaluation of the Effects of Carbon 60 Nanoparticle Exposure to Adult Zebrafish: A Behavioral and Biochemical Approach to Elucidate the Mechanism of Toxicity

(2018) Sreeja Sarasamma et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

PYCR1 and PYCR2 Interact and Collaborate with RRM2B to Protect Cells from Overt Oxidative Stress

(2016) Mei-Ling Kuo et al.   Scientific Reports

Two phases of aging separated by the Smurf transition as a public path to death

(2016) E. Dambroise et al.   Scientific Reports

CRISPR/Cas9 and TALEN-mediated knock-in approaches in zebrafish

(2014) Thomas O. Auer et al.   METHODS

Proline Mechanisms of Stress Survival

(2013) Xinwen Liang et al.   ANTIOXIDANTS & REDOX SIGNALING

Premature aging in telomerase-deficient zebrafish

(2013) M. Anchelin et al.   Disease Models & Mechanisms

Clinical and biochemical features guiding the diagnostics in neurometabolic cutis laxa

(2013) Thatjana Gardeitchik et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Zebrafish (Danio rerio) as a model for the study of aging and exercise: Physical ability and trainability decrease with age

(2013) Matthew J.H. Gilbert et al.   EXPERIMENTAL GERONTOLOGY

TALEN-mediated precise genome modification by homologous recombination in zebrafish

(2013) Yao Zu et al.   NATURE METHODS

Telomerase Is Required for Zebrafish Lifespan

(2013) Catarina M. Henriques et al.   PLoS Genetics

Automated high-throughput neurophenotyping of zebrafish social behavior

(2012) Jeremy Green et al.   JOURNAL OF NEUROSCIENCE METHODS

In vivo genome editing using a high-efficiency TALEN system

(2012) Victoria M. Bedell et al.   NATURE

Axis of ageing: telomeres, p53 and mitochondria

(2012) Ergün Sahin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Genomic deletion induced by Tol2 transposon excision in zebrafish

(2012) Peng Huang et al.   NUCLEIC ACIDS RESEARCH

Measures of Anxiety in Zebrafish (Danio rerio): Dissociation of Black/White Preference and Novel Tank Test

(2012) Rachel E. Blaser et al.   PLoS One

Intestinal barrier dysfunction links metabolic and inflammatory markers of aging to death in Drosophila

(2012) M. Rera et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modulation of Longevity and Tissue Homeostasis by the Drosophila PGC-1 Homolog

(2011) Michael Rera et al.   Cell Metabolism

Nonsense-mediated mRNA decay (NMD) in animal embryogenesis: to die or not to die, that is the question

(2011) Jungwook Hwang et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Defect in proline synthesis: pyrroline-5-carboxylate reductase 1 deficiency leads to a complex clinical phenotype with collagen and elastin abnormalities

(2011) Rita Kretz et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Proteomic Profiling of Adipose Tissue from Zmpste24−/−Mice, a Model of Lipodystrophy and Premature Aging, Reveals Major Changes in Mitochondrial Function and Vimentin Processing

(2011) Juan R. Peinado et al.   MOLECULAR & CELLULAR PROTEOMICS

Behaviour of Telomere and Telomerase during Aging and Regeneration in Zebrafish

(2011) Monique Anchelin et al.   PLoS One

Embryonic Senescence and Laminopathies in a Progeroid Zebrafish Model

(2011) Eriko Koshimizu et al.   PLoS One

Establishment of a Transgenic Zebrafish Line for Superficial Skin Ablation and Functional Validation of Apoptosis Modulators In Vivo

(2011) Chi-Fang Chen et al.   PLoS One

Proline enhances Torulopsis glabrata growth during hyperosmotic stress

(2010) Sha Xu et al.   BIOTECHNOLOGY AND BIOPROCESS ENGINEERING

RNAi screens to identify components of gene networks that modulate aging in Caenorhabditis elegans

(2010) Z. Ni et al.   Briefings in Functional Genomics

Draft genome of the medaka fish: A comprehensive resource for medaka developmental genetics and vertebrate evolutionary biology

(2010) Hiroyuki Takeda   DEVELOPMENT GROWTH & DIFFERENTIATION

Pyrroline-5-carboxylate synthase and proline biosynthesis: From osmotolerance to rare metabolic disease

(2010) Isabel Pérez-Arellano et al.   PROTEIN SCIENCE

Mutation in Pyrroline-5-Carboxylate Reductase 1 Gene in Families with Cutis Laxa Type 2

(2009) Duane L. Guernsey et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Understanding behavioral and physiological phenotypes of stress and anxiety in zebrafish

(2009) Rupert J. Egan et al.   BEHAVIOURAL BRAIN RESEARCH

Behavioral measures of anxiety in zebrafish (Danio rerio)

(2009) R.E. Blaser et al.   BEHAVIOURAL BRAIN RESEARCH

Cisd2 deficiency drives premature aging and causes mitochondria-mediated defects in mice

(2009) Y.-F. Chen et al.   GENES & DEVELOPMENT

Nonsense-Mediated mRNA Decay Effectors Are Essential for Zebrafish Embryonic Development and Survival

(2009) N. Wittkopp et al.   MOLECULAR AND CELLULAR BIOLOGY

Mutations in PYCR1 cause cutis laxa with progeroid features

(2009) Bruno Reversade et al.   NATURE GENETICS

Proline accumulation in plants: a review

(2008) Nathalie Verbruggen et al.   AMINO ACIDS

The Identification of Zebrafish Mutants Showing Alterations in Senescence-Associated Biomarkers

(2008) Shuji Kishi et al.   PLoS Genetics

Proline modulates the intracellular redox environment and protects mammalian cells against oxidative stress

(2007) Navasona Krishnan et al.   FREE RADICAL BIOLOGY AND MEDICINE