LMTK2 binds to kinesin light chains to mediate anterograde axonal transport of cdk5/p35 and LMTK2 levels are reduced in Alzheimer’s disease brains

Downregulated apoptosis and autophagy after anti-Aβ immunotherapy in Alzheimer's disease

(2018) Claire Paquet et al.   BRAIN PATHOLOGY

Biological function of Lemur tyrosine kinase 2 (LMTK2): implications in neurodegeneration

(2018) János Bencze et al.   Molecular Brain

The LMTK-family of kinases: Emerging important players in cell physiology and disease pathogenesis

(2018) Franz Wendler   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Regulation of motor proteins, axonal transport deficits and adult-onset neurodegenerative diseases

(2017) Scott T. Brady et al.   NEUROBIOLOGY OF DISEASE

CDK5-dependent activation of dynein in the axon initial segment regulates polarized cargo transport in neurons

(2017) Eva Klinman et al.   TRAFFIC

Alzheimer-related decrease in CYFIP2 links amyloid production to tau hyperphosphorylation and memory loss

(2016) Sachin Suresh Tiwari et al.   BRAIN

Conventional kinesin: Biochemical heterogeneity and functional implications in health and disease

(2016) Gerardo Morfini et al.   BRAIN RESEARCH BULLETIN

The Dynamic Localization of Cytoplasmic Dynein in Neurons Is Driven by Kinesin-1

(2016) Alison E. Twelvetrees et al.   NEURON

The light chains of kinesin-1 are autoinhibited

(2016) Yan Y. Yip et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Upregulation of calpain activity precedes tau phosphorylation and loss of synaptic proteins in Alzheimer’s disease brain

(2016) Ksenia Kurbatskaya et al.   Acta Neuropathologica Communications

A Genome-wide Gene-Expression Analysis and Database in Transgenic Mice during Development of Amyloid or Tau Pathology

(2015) Mar Matarin et al.   Cell Reports

Axonal Transport Defects in Alzheimer’s Disease

(2014) Zi-Xuan Wang et al.   MOLECULAR NEUROBIOLOGY

ER–mitochondria associations are regulated by the VAPB–PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43

(2014) Radu Stoica et al.   Nature Communications

GSK-3β, a pivotal kinase in Alzheimer disease

(2014) María Llorens-Marítin et al.   Frontiers in Molecular Neuroscience

Axonal transport deficits and neurodegenerative diseases

(2013) Stéphanie Millecamps et al.   NATURE REVIEWS NEUROSCIENCE

Structural Basis for Kinesin-1:Cargo Recognition

(2013) S. Pernigo et al.   SCIENCE

Developing Therapeutic Approaches to Tau, Selected Kinases, and Related Neuronal Protein Targets

(2013) V. M.-Y. Lee et al.   Cold Spring Harbor Perspectives in Medicine

Determination of the membrane topology of lemur tyrosine kinase 2 (LMTK2) by fluorescence protease protection

(2012) Alexander Nixon et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Deregulated Cdk5 Activity Is Involved in Inducing Alzheimer’s Disease

(2012) Varsha Shukla et al.   ARCHIVES OF MEDICAL RESEARCH

Amyotrophic lateral sclerosis-associated mutant VAPBP56S perturbs calcium homeostasis to disrupt axonal transport of mitochondria

(2012) G. M. Morotz et al.   HUMAN MOLECULAR GENETICS

Calsyntenin-1 mediates axonal transport of the amyloid precursor protein and regulates A  production

(2012) A. Vagnoni et al.   HUMAN MOLECULAR GENETICS

Cdk5/p35 phosphorylates lemur tyrosine kinase-2 to regulate protein phosphatase-1C phosphorylation and activity

(2012) Catherine Manser et al.   JOURNAL OF NEUROCHEMISTRY

Review: Axon pathology in age-related neurodegenerative disorders

(2012) R. Adalbert et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Subpixel colocalization reveals amyloid precursor protein-dependent kinesin-1 and dynein association with axonal vesicles

(2012) L. Szpankowski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cyclin-Dependent Kinases in Brain Development and Disease

(2011) Susan C. Su et al.   Annual Review of Cell and Developmental Biology

Stable Kinesin and Dynein Assemblies Drive the Axonal Transport of Mammalian Prion Protein Vesicles

(2011) Sandra E. Encalada et al.   CELL

A kinesin-1 binding motif in vaccinia virus that is widespread throughout the human genome

(2011) Mark P Dodding et al.   EMBO JOURNAL

Phosphorylation of kinesin light chain 1 at serine 460 modulates binding and trafficking of calsyntenin-1

(2011) A. Vagnoni et al.   JOURNAL OF CELL SCIENCE

Lemur tyrosine kinase-2 signalling regulates kinesin-1 light chain-2 phosphorylation and binding of Smad2 cargo

(2011) C Manser et al.   ONCOGENE

Cdk5: a multifaceted kinase in neurodegenerative diseases

(2011) Zelda H. Cheung et al.   TRENDS IN CELL BIOLOGY

A Role for Myosin VI in the Localization of Axonal Proteins

(2011) Tommy L. Lewis et al.   PLOS BIOLOGY

GSK3 signalling in neural development

(2010) Eun-Mi Hur et al.   NATURE REVIEWS NEUROSCIENCE

Molecular Motors in Neurons: Transport Mechanisms and Roles in Brain Function, Development, and Disease

(2010) Nobutaka Hirokawa et al.   NEURON

Phosphorylation of AATYK1 by Cdk5 Suppresses Its Tyrosine Phosphorylation

(2010) Koji Tsutsumi et al.   PLoS One

Vaccinia Protein F12 Has Structural Similarity to Kinesin Light Chain and Contains a Motor Binding Motif Required for Virion Export

(2010) Gareth W. Morgan et al.   PLoS Pathogens

Role of Axonal Transport in Neurodegenerative Diseases

(2008) Kurt J. De Vos et al.   Annual Review of Neuroscience

BREK/LMTK2 is a myosin VI-binding protein involved in endosomal membrane trafficking

(2008) Takeshi Inoue et al.   GENES TO CELLS