Diverse Action of Selected Statins on Skeletal Muscle Cells—An Attempt to Explain the Protective Effect of Geranylgeraniol (GGOH) in Statin-Associated Myopathy (SAM)

Geranylgeraniol Prevents Statin-Dependent Myotoxicity in C2C12 Muscle Cells through RAP1 GTPase Prenylation and Cytoprotective Autophagy

(2018) Anna Jaśkiewicz et al.   Oxidative Medicine and Cellular Longevity

The Many Faces of Rap1 GTPase

(2018) Anna Jaśkiewicz et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

The AKT/mTOR signaling pathway plays a key role in statin-induced myotoxicity

(2015) Annalisa Bonifacio et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Statin-Induced Myopathy Is Associated with Mitochondrial Complex III Inhibition

(2015) Tom J.J. Schirris et al.   Cell Metabolism

Mevalonate Pathway Blockade, Mitochondrial Dysfunction and Autophagy: A Possible Link

(2015) Paola Tricarico et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Nucleofection of Rat Pheochromocytoma PC-12 Cells with Human Mutated Beta-Amyloid Precursor Protein Gene (APP-sw) Leads to Reduced Viability, Autophagy-Like Process, and Increased Expression and Secretion of Beta Amyloid

(2015) Beata Pająk et al.   Biomed Research International

Autophagosomes, phagosomes, autolysosomes, phagolysosomes, autophagolysosomes… Wait, I’m confused

(2014) Daniel J Klionsky et al.   Autophagy

Cholesterol favors the anchorage of human dystrophin repeats 16 to 21 in membrane at physiological surface pressure

(2014) Sarah Ameziane-Le Hir et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Block of the Mevalonate Pathway Triggers Oxidative and Inflammatory Molecular Mechanisms Modulated by Exogenous Isoprenoid Compounds

(2014) Paola Tricarico et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mevalonate Kinase Deficiency and Neuroinflammation: Balance between Apoptosis and Pyroptosis

(2013) Paola Tricarico et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The role of autophagy in neurodegenerative disease

(2013) Ralph A Nixon   NATURE MEDICINE

Muscle mitochondrial metabolism and calcium signaling impairment in patients treated with statins

(2012) P. Sirvent et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Calpains — An elaborate proteolytic system

(2011) Yasuko Ono et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Simvastatin impairs ADP-stimulated respiration and increases mitochondrial oxidative stress in primary human skeletal myotubes

(2011) Hyo-Bum Kwak et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial respiratory control and early defects of oxidative phosphorylation in the failing human heart

(2011) Hélène Lemieux et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Atorvastatin treatment reduces exercise capacities in rats: involvement of mitochondrial impairments and oxidative stress

(2011) Jamal Bouitbir et al.   JOURNAL OF APPLIED PHYSIOLOGY

Transcriptional deficits in oxidative phosphorylation with statin myopathy

(2011) Monica J. Hubal et al.   MUSCLE & NERVE

Effect of simvastatin on cholesterol metabolism in C2C12 myotubes and HepG2 cells, and consequences for statin-induced myopathy

(2009) Peter James Mullen et al.   BIOCHEMICAL PHARMACOLOGY

Geranylgeraniol prevents the cytotoxic effects of mevastatin in THP-1 cells, without decreasing the beneficial effects on cholesterol synthesis

(2009) I Campia et al.   BRITISH JOURNAL OF PHARMACOLOGY

Association between statin-associated myopathy and skeletal muscle damage

(2009) M. G. Mohaupt et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

Statin-induced muscle damage and atrogin-1 induction is the result of a geranylgeranylation defect

(2009) Peirang Cao et al.   FASEB JOURNAL

Capacity of oxidative phosphorylation in human skeletal muscle

(2009) Erich Gnaiger   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Caspase-2 is required for cell death induced by cytoskeletal disruption

(2008) L H Ho et al.   ONCOGENE

Calcium and apoptosis: ER-mitochondria Ca2+ transfer in the control of apoptosis

(2008) P Pinton et al.   ONCOGENE