Progression-Related Loss of Stromal Caveolin 1 Levels Mediates Radiation Resistance in Prostate Carcinoma via the Apoptosis Inhibitor TRIAP1

Caveolin-1, cancer and therapy resistance

(2018) Julia Ketteler et al.   INTERNATIONAL JOURNAL OF CANCER

Correction: Loss of EGFR signaling-regulated miR-203 promotes prostate cancer bone metastasis and tyrosine kinase inhibitors resistance

(2018) Man Kit Siu et al.   Oncotarget

Silencing of caveolin-1 in fibroblasts as opposed to epithelial tumor cells results in increased tumor growth rate and chemoresistance in a human pancreatic cancer model

(2018) Konstantinos Kamposioras et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Glyoxalase 2 drives tumorigenesis in human prostate cells in a mechanism involving androgen receptor and p53-p21 axis

(2017) Cinzia Antognelli et al.   MOLECULAR CARCINOGENESIS

Caveolin-1: An Oxidative Stress-Related Target for Cancer Prevention

(2017) Shengqi Wang et al.   Oxidative Medicine and Cellular Longevity

Expression of Stromal Caveolin- 1 May Be a Predictor for Aggressive Behaviour of Breast Cancer

(2017) Nuket Eliyatkin et al.   PATHOLOGY & ONCOLOGY RESEARCH

MicroRNA-18a inhibits ovarian cancer growth via directly targeting TRIAP1 and IPMK

(2017) Ping Liu et al.   Oncology Letters

Progression-related loss of stromal Caveolin 1 levels fosters the growth of human PC3 xenografts and mediates radiation resistance

(2017) Andrej Panic et al.   Scientific Reports

Therapy with Multipotent Mesenchymal Stromal Cells Protects Lungs from Radiation-Induced Injury and Reduces the Risk of Lung Metastasis

(2016) Diana Klein et al.   ANTIOXIDANTS & REDOX SIGNALING

TP53 Regulated Inhibitor of Apoptosis 1 (TRIAP1) stable silencing increases late apoptosis by upregulation of caspase 9 and APAF1 in RPMI8226 multiple myeloma cell line

(2016) Veruska L. Fook-Alves et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Targeting tumor microenvironment in cancer therapy

(2016) Shree Ram Singh et al.   CANCER LETTERS

Tumor microenvironment and cancer therapy resistance

(2016) Yu Sun   CANCER LETTERS

Lysosomes as mediators of drug resistance in cancer

(2016) Benny Zhitomirsky et al.   DRUG RESISTANCE UPDATES

Thinking in three dimensions: discovering reciprocal signaling between the extracellular matrix and nucleus and the wisdom of microenvironment and tissue architecture

(2016) Mina J. Bissell   MOLECULAR BIOLOGY OF THE CELL

High Caveolin-1 Expression in Tumor Stroma Is Associated with a Favourable Outcome in Prostate Cancer Patients Managed by Watchful Waiting

(2016) Peter Hammarsten et al.   PLoS One

Overexpression of Mitochondria Mediator Gene TRIAP1 by miR-320b Loss Is Associated with Progression in Nasopharyngeal Carcinoma

(2016) Yingqin Li et al.   PLoS Genetics

Intravital Imaging Reveals How BRAF Inhibition Generates Drug-Tolerant Microenvironments with High Integrin β1/FAK Signaling

(2015) Eishu Hirata et al.   CANCER CELL

The role for autophagy in cancer

(2015) Eileen White   JOURNAL OF CLINICAL INVESTIGATION

Apoptosis inhibitor TRIAP1 is a novel effector of drug resistance

(2015) CAROLINE ADAMS et al.   ONCOLOGY REPORTS

Endothelial Caveolin-1 regulates the radiation response of epithelial prostate tumors

(2015) D Klein et al.   Oncogenesis

MicroRNA silencing for cancer therapy targeted to the tumour microenvironment

(2014) Christopher J. Cheng et al.   NATURE

Value of caveolin-1 in cancer progression and prognosis: Emphasis on cancer-associated fibroblasts, human cancer cells and mechanism of caveolin-1 expression (Review)

(2014) DALI CHEN et al.   Oncology Letters

Overexpression of Caveolin-1 in Cancer-Associated Fibroblasts Predicts Good Outcome in Breast Cancer

(2013) Shan-Wei Wang et al.   Breast Care

Loss of caveolin-1 in prostate cancer stroma correlates with reduced relapse-free survival and is functionally relevant to tumour progression

(2013) Gustavo Ayala et al.   JOURNAL OF PATHOLOGY

A Genetic Screen Identifies TCF3/E2A and TRIAP1 as Pathway-Specific Regulators of the Cellular Response to p53 Activation

(2013) Zdenek Andrysik et al.   Cell Reports

Tumor Microenvironment Complexity: Emerging Roles in Cancer Therapy

(2012) M. A. Swartz et al.   CANCER RESEARCH

Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion

(2012) Ravid Straussman et al.   NATURE

The microenvironment and resistance to personalized cancer therapy

(2012) Shigeo Masuda et al.   Nature Reviews Clinical Oncology

Cancer-associated lysosomal changes: friends or foes?

(2012) T Kallunki et al.   ONCOGENE

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

An absence of stromal caveolin-1 is associated with advanced prostate cancer, metastatic disease spread and epithelial Akt activation

(2011) Dolores Di Vizio et al.   CELL CYCLE

Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression

(2011) Mina J Bissell et al.   NATURE MEDICINE

Oxidative stress in cancer associated fibroblasts drives tumor-stroma co-evolution

(2010) Ubaldo E. Martinez-Outschoorn et al.   CELL CYCLE

Tumor cells induce the cancer associated fibroblast phenotype via caveolin-1 degradation: Implications for breast cancer and DCIS therapy with autophagy inhibitors

(2010) Ubaldo E. Martinez-Outschoorn et al.   CELL CYCLE

Overexpression of Caveolin-1 in Lymphoblastoid TK6 Cells Enhances Proliferation After Irradiation with Clinically Relevant Doses

(2010) David Barzan et al.   STRAHLENTHERAPIE UND ONKOLOGIE

An Absence of Stromal Caveolin-1 Expression Predicts Early Tumor Recurrence and Poor Clinical Outcome in Human Breast Cancers

(2009) Agnieszka K. Witkiewicz et al.   AMERICAN JOURNAL OF PATHOLOGY

Sensitization to the Lysosomal Cell Death Pathway by Oncogene-Induced Down-regulation of Lysosome-Associated Membrane Proteins 1 and 2

(2008) N. Fehrenbacher et al.   CANCER RESEARCH