Understanding Human-Virus Protein-Protein Interactions Using a Human Protein Complex-Based Analysis Framework

A multiprotein supercomplex controlling oncogenic signalling in lymphoma

(2018) James D. Phelan et al.   NATURE

Interrogation of Mammalian Protein Complex Structure, Function, and Membership Using Genome-Scale Fitness Screens

(2018) Joshua Pan et al.   Cell Systems

Integration of over 9,000 mass spectrometry experiments builds a global map of human protein complexes

(2017) Kevin Drew et al.   Molecular Systems Biology

Host with the most: Targeting host cells instead of pathogens to fight infectious disease

(2017) Amanda B. Keener   NATURE MEDICINE

OUP accepted manuscript

(2017)   NUCLEIC ACIDS RESEARCH

DGIdb 3.0: a redesign and expansion of the drug–gene interaction database

(2017) Kelsy C Cotto et al.   NUCLEIC ACIDS RESEARCH

DrugBank 5.0: a major update to the DrugBank database for 2018

(2017) David S Wishart et al.   NUCLEIC ACIDS RESEARCH

A Global Interactome Map of the Dengue Virus NS1 Identifies Virus Restriction and Dependency Host Factors

(2017) Mohamed Lamine Hafirassou et al.   Cell Reports

An analysis of human microbe–disease associations

(2016) Wei Ma et al.   BRIEFINGS IN BIOINFORMATICS

A high-resolution transcriptome map of cell cycle reveals novel connections between periodic genes and cancer

(2016) Daniel Dominguez et al.   CELL RESEARCH

A review on host–pathogen interactions: classification and prediction

(2016) R. Sen et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

The BioGRID interaction database: 2017 update

(2016) Andrew Chatr-aryamontri et al.   NUCLEIC ACIDS RESEARCH

g:Profiler—a web server for functional interpretation of gene lists (2016 update)

(2016) Jüri Reimand et al.   NUCLEIC ACIDS RESEARCH

HPIDB 2.0: a curated database for host–pathogen interactions

(2016) Mais G. Ammari et al.   Database-The Journal of Biological Databases and Curation

Systems Biology-Based Investigation of Cellular Antiviral Drug Targets Identified by Gene-Trap Insertional Mutagenesis

(2016) Feixiong Cheng et al.   PLoS Computational Biology

Local Action with Global Impact: Highly Similar Infection Patterns of Human Viruses and Bacteriophages

(2016) Rachelle Mariano et al.   mSystems

Structure, Dynamics, Assembly, and Evolution of Protein Complexes

(2015) Joseph A. Marsh et al.   Annual Review of Biochemistry

A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances

(2015) Marco Y. Hein et al.   CELL

The BioPlex Network: A Systematic Exploration of the Human Interactome

(2015) Edward L. Huttlin et al.   CELL

Subversion of Cell Cycle Regulatory Mechanisms by HIV

(2015) Andrew P. Rice et al.   Cell Host & Microbe

Panorama of ancient metazoan macromolecular complexes

(2015) Cuihong Wan et al.   NATURE

Gene activity in primary T cells infected with HIV89.6: intron retention and induction of genomic repeats

(2015) Scott Sherrill-Mix et al.   Retrovirology

Gene essentiality and synthetic lethality in haploid human cells

(2015) V. A. Blomen et al.   SCIENCE

Influenza Virus-Host Interactome Screen as a Platform for Antiviral Drug Development

(2014) Tokiko Watanabe et al.   Cell Host & Microbe

Different subunits belonging to the same protein complex often exhibit discordant expression levels and evolutionary properties

(2014) Or Matalon et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

A draft map of the human proteome

(2014) Min-Sik Kim et al.   NATURE

EHFPI: a database and analysis resource of essential host factors for pathogenic infection

(2014) Yang Liu et al.   NUCLEIC ACIDS RESEARCH

Cyclebase 3.0: a multi-organism database on cell-cycle regulation and phenotypes

(2014) Alberto Santos et al.   NUCLEIC ACIDS RESEARCH

An Integrated Map of HIV-Human Protein Complexes that Facilitate Viral Infection

(2014) Dorothea Emig-Agius et al.   PLoS One

Current progress in antiviral strategies

(2014) Zhiyong Lou et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Targeting Host Factors to Treat West Nile and Dengue Viral Infections

(2014) Manoj Krishnan et al.   Viruses-Basel

Influenza Viruses and mRNA Splicing: Doing More with Less

(2014) J. Dubois et al.   mBio

Virus-host interactomics: new insights and opportunities for antiviral drug discovery

(2014) Benoît de Chassey et al.   Genome Medicine

The Genotype-Tissue Expression (GTEx) project

(2013) John Lonsdale et al.   NATURE GENETICS

Protein Complex-Based Analysis Framework for High-Throughput Data Sets

(2013) A. Vinayagam et al.   Science Signaling

InnateDB: systems biology of innate immunity and beyond—recent updates and continuing curation

(2012) Karin Breuer et al.   NUCLEIC ACIDS RESEARCH

Global landscape of HIV–human protein complexes

(2011) Stefanie Jäger et al.   NATURE

Viral subversion of the host protein synthesis machinery

(2011) Derek Walsh et al.   NATURE REVIEWS MICROBIOLOGY

The IntAct molecular interaction database in 2012

(2011) S. Kerrien et al.   NUCLEIC ACIDS RESEARCH

Scaffold Proteins: Hubs for Controlling the Flow of Cellular Information

(2011) M. C. Good et al.   SCIENCE

Can medical genetics and evolutionary biology inspire drug target identification?

(2011) Zhong-Yi Wang et al.   TRENDS IN MOLECULAR MEDICINE

Chim3 confers survival advantage to CD4+ T cells upon HIV-1 infection by preventing HIV-1 DNA integration and HIV-1-induced G2 cell-cycle delay

(2010) S. Porcellini et al.   BLOOD

HIV-1 Vif promotes the G1- to S-phase cell-cycle transition

(2010) J. Wang et al.   BLOOD

CORUM: the comprehensive resource of mammalian protein complexes—2009

(2009) Andreas Ruepp et al.   NUCLEIC ACIDS RESEARCH

How HIV changes its tropism: evolution and adaptation?

(2009) Donald E Mosier   Current Opinion in HIV and AIDS

Global Analysis of Host-Pathogen Interactions that Regulate Early-Stage HIV-1 Replication

(2008) Renate König et al.   CELL

Genome-Scale RNAi Screen for Host Factors Required for HIV Replication

(2008) Honglin Zhou et al.   Cell Host & Microbe

Innate immunity to virus infection

(2008) Osamu Takeuchi et al.   IMMUNOLOGICAL REVIEWS

Hepatitis C virus infection protein network

(2008) B de Chassey et al.   Molecular Systems Biology

Identification of Host Proteins Required for HIV Infection Through a Functional Genomic Screen

(2008) Abraham L. Brass et al.   SCIENCE