Determinant roles of dendritic cell-expressed Notch Delta-like and Jagged ligands on anti-tumor T cell immunity

Notch Signaling as a Regulator of the Tumor Immune Response: To Target or Not To Target?

(2018) Mahnaz Janghorban et al.   Frontiers in Immunology

Update on the current revolution in cancer immunotherapy

(2018) Ariana Nicole Renrick et al.   Immunotherapy

Novel TCR-Mediated Mechanisms of Notch Activation and Signaling

(2017) Martin Peter Steinbuck et al.   JOURNAL OF IMMUNOLOGY

Notch-mediated conversion of activated T cells into stem cell memory-like T cells for adoptive immunotherapy

(2017) Taisuke Kondo et al.   Nature Communications

IL-6 and PD-L1 antibody blockade combination therapy reduces tumour progression in murine models of pancreatic cancer

(2016) Thomas A Mace et al.   GUT

Transcription Factor KLF2 in Dendritic Cells Downregulates Th2 Programming via the HIF-1α/Jagged2/Notch Axis

(2016) Ye Xiong et al.   mBio

Multivalent Forms of the Notch Ligand DLL-1 Enhance Antitumor T-cell Immunity in Lung Cancer and Improve Efficacy of EGFR-Targeted Therapy

(2015) A. K. Biktasova et al.   CANCER RESEARCH

Notch Signaling Regulates Antigen Sensitivity of Naive CD4+ T Cells by Tuning Co-stimulation

(2015) Karen Laky et al.   IMMUNITY

Bortezomib enhances expression of effector molecules in anti-tumor CD8+ T lymphocytes by promoting Notch-nuclear factor-κB crosstalk

(2015) Menaka C. Thounaojam et al.   Oncotarget

Jagged-1 is required for the expansion of CD4+ CD25+ FoxP3+ regulatory T cells and tolerogenic dendritic cells by murine mesenchymal stromal cells

(2015) Emer F Cahill et al.   Stem Cell Research & Therapy

Suppression of Th2 Cell Development by Notch Ligands Delta1 and Delta4

(2014) J. Sun et al.   JOURNAL OF IMMUNOLOGY

Th2 Differentiation Is Unaffected by Jagged2 Expression on Dendritic Cells

(2014) C. M. Krawczyk et al.   JOURNAL OF IMMUNOLOGY

Rescue of Notch-1 Signaling in Antigen-Specific CD8+ T Cells Overcomes Tumor-Induced T-cell Suppression and Enhances Immunotherapy in Cancer

(2014) R. A. Sierra et al.   Cancer Immunology Research

Jagged2-signaling promotes IL-6-dependent transplant rejection

(2013) Leonardo V. Riella et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Notch Simultaneously Orchestrates Multiple Helper T Cell Programs Independently of Cytokine Signals

(2013) Will Bailis et al.   IMMUNITY

Notch Signaling Regulates Follicular Helper T Cell Differentiation

(2013) F. Auderset et al.   JOURNAL OF IMMUNOLOGY

Notch signaling regulates PD-1 expression during CD8+ T-cell activation

(2012) Mélissa Mathieu et al.   IMMUNOLOGY AND CELL BIOLOGY

Notch Signalling Regulates Cytokine Production by CD8+ and CD4+ T Cells

(2012) D. Sauma et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Resuscitating Cancer Immunosurveillance: Selective Stimulation of DLL1-Notch Signaling in T cells Rescues T-cell Function and Inhibits Tumor Growth

(2011) Y. Huang et al.   CANCER RESEARCH

Notch and inflammatory T-cell response: new developments and challenges

(2011) Kazuhiro Mochizuki et al.   Immunotherapy

Notch Signaling Regulates Mouse and Human Th17 Differentiation

(2011) S. Keerthivasan et al.   JOURNAL OF IMMUNOLOGY

Differential Regulation of Notch Ligands in Dendritic Cells upon Interaction with T Helper Cells

(2011) D. Sauma et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Generation of mice with a conditional null allele of the Jagged2 gene

(2010) Jingxia Xu et al.   GENESIS

Notch2 Signaling Is Required for Potent Antitumor Immunity In Vivo

(2010) K. Sugimoto et al.   JOURNAL OF IMMUNOLOGY

The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism

(2009) Raphael Kopan et al.   CELL

Cutting Edge: Plasmacytoid Dendritic Cells Induce IL-10 Production in T Cells via the Delta-Like-4/Notch Axis

(2009) N. Kassner et al.   JOURNAL OF IMMUNOLOGY

Regulation of T Cell Activation by Notch Ligand, DLL4, Promotes IL-17 Production and Rorc Activation

(2009) S. Mukherjee et al.   JOURNAL OF IMMUNOLOGY

Adenosine receptors in regulation of dendritic cell differentiation and function

(2008) S. V. Novitskiy et al.   BLOOD

Notch1 and TGF 1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells

(2008) J. B. Samon et al.   BLOOD

Human immature myeloid dendritic cells trigger a TH2-polarizing program via Jagged-1/Notch interaction

(2008) Francesco Liotta et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY