An Ssd1 Homolog Impacts Trehalose and Chitin Biosynthesis and Contributes to Virulence in Aspergillus fumigatus

Central Role of the Trehalose Biosynthesis Pathway in the Pathogenesis of Human Fungal Infections: Opportunities and Challenges for Therapeutic Development

(2017) Arsa Thammahong et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Aspergillus fumigatus Trehalose-Regulatory Subunit Homolog Moonlights To Mediate Cell Wall Homeostasis through Modulation of Chitin Synthase Activity

(2017) Arsa Thammahong et al.   mBio

Filamentous fungal carbon catabolite repression supports metabolic plasticity and stress responses essential for disease progression

(2017) Sarah R. Beattie et al.   PLoS Pathogens

Epidemiology and Molecular Characterizations of Azole Resistance in Clinical and Environmental Aspergillus fumigatus Isolates from China

(2016) Yong Chen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Azole-resistant Aspergillus fumigatus in Denmark: a laboratory-based study on resistance mechanisms and genotypes

(2016) R.H. Jensen et al.   CLINICAL MICROBIOLOGY AND INFECTION

Regulation of Neurospora crassa cell wall remodeling via the cot-1 pathway is mediated by gul-1

(2016) Inbal Herold et al.   CURRENT GENETICS

Complex Haploinsufficiency-Based Genetic Analysis of the NDR/Lats Kinase Cbk1 Provides Insight into Its Multiple Functions in Candida albicans

(2016) S. Saputo et al.   GENETICS

Multi-azole resistant Aspergillus fumigatus harboring Cyp51A TR46/Y121F/T289A isolated in Japan

(2016) Daisuke Hagiwara et al.   JOURNAL OF INFECTION AND CHEMOTHERAPY

Prevalence of azole-resistantAspergillus fumigatusin the environment of Thailand

(2016) Marut Tangwattanachuleeporn et al.   MEDICAL MYCOLOGY

Examination of cyp51A and cyp51B expression level of the first Polish azole resistant clinical Aspergillus fumigatus isolate

(2015) Anna Brillowska-Dąbrowska et al.   ACTA BIOCHIMICA POLONICA

Azole Resistance in Aspergillus fumigatus Clinical Isolates from an Italian Culture Collection

(2015) Cristina Lazzarini et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

First Description of Azole-Resistant Aspergillus fumigatus Due to TR46/Y121F/T289A Mutation in France

(2015) Rose-Anne Lavergne et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Nationwide Surveillance of Azole Resistance in Aspergillus Diseases

(2015) Edith Vermeulen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The NDR Kinase Cbk1 Downregulates the Transcriptional Repressor Nrg1 through the mRNA-Binding Protein Ssd1 in Candida albicans

(2015) Hye-Jeong Lee et al.   EUKARYOTIC CELL

High prevalence of azole resistance inAspergillus fumigatusisolates from high-risk patients

(2015) J. Fuhren et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Emergence of azole-resistant invasive aspergillosis in HSCT recipients in Germany

(2015) J. Steinmann et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

First Detection of TR34 L98H and TR46 Y121F T289A Cyp51 Mutations in Aspergillus fumigatus Isolates in the United States

(2015) Nathan P. Wiederhold et al.   JOURNAL OF CLINICAL MICROBIOLOGY

First determination of azole resistance in Aspergillus fumigatus strains carrying the TR34/L98H mutations in Turkey

(2015) Gülşah Ece Özmerdiven et al.   JOURNAL OF INFECTION AND CHEMOTHERAPY

Multi-triazole-resistantAspergillus fumigatusinfections in Australia

(2015) Sarah E. Kidd et al.   MYCOSES

Azole-resistantAspergillus fumigatusisolates carrying TR34/L98H mutations in Taiwan

(2015) Chi-Jung Wu et al.   MYCOSES

The Aspergillus fumigatus cell wall integrity signaling pathway: drug target, compensatory pathways, and virulence

(2015) Vito Valiante et al.   Frontiers in Microbiology

Occurrence of triazole-resistant Aspergillus fumigatus with TR34/L98H mutations in outdoor and hospital environment in Kuwait

(2014) Suhail Ahmad et al.   ENVIRONMENTAL RESEARCH

Multi-azole-resistant Aspergillus fumigatus in the environment in Tanzania

(2014) A. Chowdhary et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Iterative breakthrough invasive aspergillosis due to TR(34)/L98H azole-resistantAspergillus fumigatusandEmericella sublatain a single hematopoietic stem cell transplant patient

(2014) F.S. de Fontbrune et al.   Transplant Infectious Disease

Fungal Chitin Dampens Inflammation through IL-10 Induction Mediated by NOD2 and TLR9 Activation

(2014) Jeanette Wagener et al.   PLoS Pathogens

Environmental study of azole-resistantAspergillus fumigatuswith TR34/L98H mutations in thecyp51A gene in Iran

(2013) Hamid Badali et al.   MYCOSES

Aspergillus Galactosaminogalactan Mediates Adherence to Host Constituents and Conceals Hyphal β-Glucan from the Immune System

(2013) Fabrice N. Gravelat et al.   PLoS Pathogens

Dsc Orthologs Are Required for Hypoxia Adaptation, Triazole Drug Responses, and Fungal Virulence in Aspergillus fumigatus

(2012) Sven D. Willger et al.   EUKARYOTIC CELL

Hypoxia enhances innate immune activation to Aspergillus fumigatus through cell wall modulation

(2012) Kelly M. Shepardson et al.   MICROBES AND INFECTION

Hidden Killers: Human Fungal Infections

(2012) G. D. Brown et al.   Science Translational Medicine

High Prevalence of Azole-Resistant Aspergillus fumigatus in Adults with Cystic Fibrosis Exposed to Itraconazole

(2011) Pierre-Régis Burgel et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Osmotic stabilizer-coupled suppression of NDR defects is dependent on the calcium–calcineurin signaling cascade in Aspergillus nidulans

(2011) Lina Gao et al.   CELLULAR SIGNALLING

Isolation of multiple-triazole-resistant Aspergillus fumigatus strains carrying the TR/L98H mutations in the cyp51A gene in India

(2011) A. Chowdhary et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

In vivo Hypoxia and a Fungal Alcohol Dehydrogenase Influence the Pathogenesis of Invasive Pulmonary Aspergillosis

(2011) Nora Grahl et al.   PLoS Pathogens

Transcriptional Regulation of Chitin Synthases by Calcineurin Controls Paradoxical Growth of Aspergillus fumigatus in Response to Caspofungin

(2010) J. R. Fortwendel et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Progressive Activation of CyclinB1-Cdk1 Coordinates Entry to Mitosis

(2010) Olivier Gavet et al.   DEVELOPMENTAL CELL

Role of Trehalose Biosynthesis in Aspergillus fumigatus Development, Stress Response, and Virulence

(2010) N. Al-Bader et al.   INFECTION AND IMMUNITY

Trehalose 6-phosphate phosphatase is required for cell wall integrity and fungal virulence but not trehalose biosynthesis in the human fungal pathogen Aspergillus fumigatus

(2010) Srisombat Puttikamonkul et al.   MOLECULAR MICROBIOLOGY

SSD1Is Integral to Host Defense Peptide Resistance inCandida albicans

(2008) Kimberly D. Gank et al.   EUKARYOTIC CELL

Depletion of the MobB and CotA complex in Aspergillus nidulans causes defects in polarity maintenance that can be suppressed by the environment stress

(2008) Jie Shi et al.   FUNGAL GENETICS AND BIOLOGY

Update on Azole Antifungals

(2008) Dimitrios Zonios et al.   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

Diverse RNA-Binding Proteins Interact with Functionally Related Sets of RNAs, Suggesting an Extensive Regulatory System

(2008) Daniel J Hogan et al.   PLOS BIOLOGY