Synthesis, Structure Elucidation, Homology Modeling and Antifilarial Activity of 7‐Benzamidocoumarin Derivatives

Resolution, absolute configuration and antifilarial activity of coumarinyl amino alcohols

(2017) Priyanka et al.   TETRAHEDRON-ASYMMETRY

Two decades of antifilarial drug discovery: a review

(2017) Jaiprakash N. Sangshetti et al.   RSC Advances

Chitin Is Endogenously Produced in Vertebrates

(2015) W. Joyce Tang et al.   CURRENT BIOLOGY

Synthesis and biological evaluation of 4-oxycoumarin derivatives as a new class of antifilarial agents

(2015) Sweta Misra et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Exploiting the Polypharmacology of ß-Carbolines to Disrupt O. volvulus Molting

(2015) Major Gooyit et al.   ACS Medicinal Chemistry Letters

Onchocerca volvulus Molting Inhibitors Identified through Scaffold Hopping

(2015) Major Gooyit et al.   ACS Infectious Diseases

Dual Protonophore–Chitinase Inhibitors Dramatically Affect O. volvulus Molting

(2014) Major Gooyit et al.   JOURNAL OF MEDICINAL CHEMISTRY

Filariasis: Current Status, Treatment and Recent Advances in Drug Development

(2012) D. Katiyar et al.   CURRENT MEDICINAL CHEMISTRY

Substrate specificity of acetoxy derivatives of coumarins and quinolones towards Calreticulin mediated transacetylation: Investigations on antiplatelet function

(2011) Abha Kathuria et al.   BIOORGANIC & MEDICINAL CHEMISTRY

The cellular basis of chitin synthesis in fungi and insects: Common principles and differences

(2011) Hans Merzendorfer   EUROPEAN JOURNAL OF CELL BIOLOGY

A computational analysis of the binding mode of closantel as inhibitor of the Onchocerca volvulus chitinase: insights on macrofilaricidal drug design

(2011) Aldo Segura-Cabrera et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Design, Synthesis, and Biological Evaluation of Imidazolyl Derivatives of 4,7-Disubstituted Coumarins as Aromatase Inhibitors Selective over 17-α-Hydroxylase/C17−20 Lyase

(2011) Angela Stefanachi et al.   JOURNAL OF MEDICINAL CHEMISTRY

Design, Synthesis, and Biological Activities of Closantel Analogues: Structural Promiscuity and Its Impact onOnchocerca volvulus

(2011) Amanda L. Garner et al.   JOURNAL OF MEDICINAL CHEMISTRY

Integrated Dataset of Screening Hits against Multiple Neglected Disease Pathogens

(2011) Solomon Nwaka et al.   PLoS Neglected Tropical Diseases

Coumarins: Old Compounds with Novel Promising Therapeutic Perspectives

(2010) M. Riveiro et al.   CURRENT MEDICINAL CHEMISTRY

Lymphatic filariasis and onchocerciasis

(2010) Mark J Taylor et al.   LANCET

Repositioning of an existing drug for the neglected tropical disease Onchocerciasis

(2010) Christian Gloeckner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Chitinase is stored and secreted from the inner body of microfilariae and has a role in exsheathment in the parasitic nematode Brugia malayi

(2008) Yang Wu et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY