Exercise ameliorates the FGF21–adiponectin axis impairment in diet-induced obese mice

Exercise Alleviates Obesity-Induced Metabolic Dysfunction via Enhancing FGF21 Sensitivity in Adipose Tissues

(2019) Leiluo Geng et al.   Cell Reports

Exercise training prevents high-fat diet-induced adipose tissue remodeling by promoting capillary density and macrophage polarization

(2019) Sarkawt Kolahdouzi et al.   LIFE SCIENCES

Fibroblast growth factor 21 increases insulin sensitivity through specific expansion of subcutaneous fat

(2018) Huating Li et al.   Nature Communications

The ominous triad of adipose tissue dysfunction: inflammation, fibrosis, and impaired angiogenesis

(2017) Clair Crewe et al.   JOURNAL OF CLINICAL INVESTIGATION

IL-1β inhibits β-Klotho expression and FGF19 signaling in hepatocytes

(2016) Yueshui Zhao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Fibroblast growth factor 21 improves hepatic insulin sensitivity by inhibiting mammalian target of rapamycin complex 1 in mice

(2016) Qi Gong et al.   HEPATOLOGY

Exercise-Induced Secretion of FGF21 and Follistatin Are Blocked by Pancreatic Clamp and Impaired in Type 2 Diabetes

(2016) Jakob Schiøler Hansen et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The FGF21–adiponectin axis in controlling energy and vascular homeostasis

(2016) Xiaoyan Hui et al.   Journal of Molecular Cell Biology

A Novel Role for Subcutaneous Adipose Tissue in Exercise-Induced Improvements in Glucose Homeostasis

(2015) Kristin I. Stanford et al.   DIABETES

Hepatic insulin resistance and increased hepatic glucose production in mice lackingFgf21

(2015) João Paulo G Camporez et al.   JOURNAL OF ENDOCRINOLOGY

Loss of fibroblast growth factor 21 action induces insulin resistance, pancreatic islet hyperplasia and dysfunction in mice

(2015) W Y So et al.   Cell Death & Disease

Glucagon-to-insulin ratio is pivotal for splanchnic regulation of FGF-21 in humans

(2015) Jakob Schiøler Hansen et al.   Molecular Metabolism

Exercise Ameliorates Insulin Resistance via Ca2+Signals Distinct From Those of Insulin for GLUT4 Translocation in Skeletal Muscles

(2014) Dae-Ryoung Park et al.   DIABETES

Circulating FGF21 Is Liver Derived and Enhances Glucose Uptake During Refeeding and Overfeeding

(2014) K. R. Markan et al.   DIABETES

Increased Skeletal Muscle Capillarization After Aerobic Exercise Training and Weight Loss Improves Insulin Sensitivity in Adults With IGT

(2014) Steven J. Prior et al.   DIABETES CARE

Adiponectin Mediates the Metabolic Effects of FGF21 on Glucose Homeostasis and Insulin Sensitivity in Mice

(2013) Zhuofeng Lin et al.   Cell Metabolism

An FGF21-Adiponectin-Ceramide Axis Controls Energy Expenditure and Insulin Action in Mice

(2013) William L. Holland et al.   Cell Metabolism

The Effects of LY2405319, an FGF21 Analog, in Obese Human Subjects with Type 2 Diabetes

(2013) Gregory Gaich et al.   Cell Metabolism

Profilin-1 Haploinsufficiency Protects Against Obesity-Associated Glucose Intolerance and Preserves Adipose Tissue Immune Homeostasis

(2013) G. R. Romeo et al.   DIABETES

Effect of endurance training on skeletal muscle myokine expression in obese men: identification of apelin as a novel myokine

(2013) A Besse-Patin et al.   INTERNATIONAL JOURNAL OF OBESITY

Acute Exercise Induces FGF21 Expression in Mice and in Healthy Humans

(2013) Kook Hwan Kim et al.   PLoS One

βKlotho Is Required for Fibroblast Growth Factor 21 Effects on Growth and Metabolism

(2012) Xunshan Ding et al.   Cell Metabolism

TNF-α Represses β-Klotho Expression and Impairs FGF21 Action in Adipose Cells: Involvement of JNK1 in the FGF21 Pathway

(2012) Julieta Díaz-Delfín et al.   ENDOCRINOLOGY

Effects of a three-month combined exercise programme on fibroblast growth factor 21 and fetuin-A levels and arterial stiffness in obese women

(2011) Sae Jeong Yang et al.   CLINICAL ENDOCRINOLOGY

Endurance exercise training increases APPL1 expression and improves insulin signaling in the hepatic tissue of diet-induced obese mice, independently of weight loss

(2011) R. Marinho et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Obesity Is a Fibroblast Growth Factor 21 (FGF21)-Resistant State

(2010) f. M. Fisher et al.   DIABETES

Total and high–molecular weight adiponectin in women with the polycystic ovary syndrome

(2010) Edmond P. Wickham et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Effects of Exercise Training Intensity on Pancreatic  -Cell Function

(2009) C. A. Slentz et al.   DIABETES CARE

Global estimates of the prevalence of diabetes for 2010 and 2030

(2009) J.E. Shaw et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Serum FGF21 Levels Are Increased in Obesity and Are Independently Associated With the Metabolic Syndrome in Humans

(2008) X. Zhang et al.   DIABETES

βKlotho Is Required for Fibroblast Growth Factor (FGF) 21 Signaling through FGF Receptor (FGFR) 1c and FGFR3c

(2008) Masashi Suzuki et al.   MOLECULAR ENDOCRINOLOGY